hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_13244.1
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| CFAP20DC | Protein CFAP20DC (Uncharacterized protein C3orf67) | 2 | UniProt NCBI |
| FKBP15 | FK506-binding protein 15 (FKBP-15) (133 kDa FK506-binding protein) (133 kDa FKBP) (FKBP-133) (WASP- and FKBP-like protein) (WAFL) | 5 | UniProt NCBI |
| VPS26B | Vacuolar protein sorting-associated protein 26B (Vesicle protein sorting 26B) | 3 | UniProt NCBI |
| VPS26A | Vacuolar protein sorting-associated protein 26A (Vesicle protein sorting 26A) (hVPS26) | 5 | UniProt NCBI |
| TBC1D5 | TBC1 domain family member 5 | 5 | UniProt NCBI |
| VPS29 | Vacuolar protein sorting-associated protein 29 (hVPS29) (PEP11 homolog) (Vesicle protein sorting 29) | 5 | UniProt NCBI |
| ANKRD27 | Ankyrin repeat domain-containing protein 27 (VPS9 domain-containing protein) | 5 | UniProt NCBI |
| VPS35 | Vacuolar protein sorting-associated protein 35 (hVPS35) (Maternal-embryonic 3) (Vesicle protein sorting 35) | 5 | UniProt NCBI |
| LRRC73 | Leucine-rich repeat-containing protein 73 | 3 | UniProt NCBI |
| TAS2R19 | Taste receptor type 2 member 19 (Taste receptor type 2 member 23) (Taste receptor type 2 member 48) (T2R48) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0030906 | 5.52565251192e-09 | 0.4 | VPS26B VPS29 VPS35 VPS26A | retromer, cargo-selective complex |
| CORUM:656 | 1.68385473419e-08 | 0.3 | VPS26A VPS29 VPS35 | VPS35-VPS29-VPS26A complex |
| GO:0030904 | 2.62799829276e-08 | 0.5 | VPS26B TBC1D5 VPS29 VPS35 VPS26A | retromer complex |
| CORUM:657 | 1.68264493604e-07 | 0.3 | VPS26A VPS29 VPS35 | Retromer complex (SNX1, SNX2, VPS35, VPS29, VPS26A) |
| CORUM:1059 | 1.68264493604e-07 | 0.3 | VPS26A VPS29 VPS35 | Retromer complex (SNX1, SNX2, VPS35, VPS29, VPS26A) |
| CORUM:1060 | 1.68264493604e-07 | 0.3 | VPS26B VPS29 VPS35 | Retromer complex (SNX1, SNX2, VPS35, VPS29, VPS26B) |
| GO:0042147 | 6.84879862683e-05 | 0.5 | VPS26B TBC1D5 VPS29 VPS35 VPS26A | retrograde transport, endosome to Golgi |
| GO:0097422 | 0.000115261178119 | 0.3 | VPS26A ANKRD27 VPS35 | tubular endosome |
| REAC:R-HSA-3238698 | 0.000127150506262 | 0.3 | VPS26A VPS29 VPS35 | WNT ligand biogenesis and trafficking |
| GO:0016197 | 0.000202236537263 | 0.6 | VPS26B VPS26A ANKRD27 VPS35 TBC1D5 VPS29 | endosomal transport |
| GO:0016482 | 0.000401127164141 | 0.5 | VPS26B TBC1D5 VPS29 VPS35 VPS26A | cytosolic transport |
| KEGG:04144 | 0.000596735285093 | 0.4 | VPS26B VPS29 VPS35 VPS26A | Endocytosis |
| GO:0032456 | 0.0065610560312 | 0.4 | VPS26A VPS29 VPS35 ANKRD27 | endocytic recycling |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| VPS26B | VPS26A | 1.0 | 0.106 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 fraction |
| VPS26A | VPS29 | 1.0 | 0.838 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM Guru bioplex3_WMM hein () bioplex3_HCT116 gupta_WMM fraction |
| VPS26B | VPS29 | 1.0 | 0.096 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM Guru bioplex3_WMM hein () bioplex3_HCT116 fraction boldt_WMM |
| VPS26A | VPS35 | 1.0 | 0.802 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM Guru bioplex3_WMM hein () bioplex3_HCT116 gupta_WMM fraction |
| VPS26B | VPS35 | 1.0 | 0.084 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM Guru bioplex3_WMM boldt hein () fraction boldt_WMM |
| VPS29 | VPS35 | 1.0 | 0.88 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM Guru bioplex3_WMM bioplex3_HCT116 gupta_WMM fraction boldt_WMM |
| VPS26A | TBC1D5 | 1.0 | 0.112 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM hein () bioplex3_HCT116 gupta_WMM |
| VPS29 | TBC1D5 | 1.0 | 0.094 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 gupta_WMM |
| VPS26B | TBC1D5 | 0.999 | 0.046 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM hein () |
| VPS35 | TBC1D5 | 0.999 | 0.142 | hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM gupta_WMM WMM_only |
| TBC1D5 | LRRC73 | 0.998 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| VPS29 | ANKRD27 | 0.995 | 0.098 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| ANKRD27 | VPS35 | 0.988 | 0.174 | hein_WMM bioplex_WMM bioplex3_WMM WMM_only |
| VPS26B | ANKRD27 | 0.985 | 0.04 | hein_WMM bioplex_WMM bioplex3_WMM hein () |
| TBC1D5 | FKBP15 | 0.983 | 0.096 | hein_WMM bioplex3_WMM youn_WMM WMM_only |
| VPS26A | LRRC73 | 0.983 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| VPS29 | FKBP15 | 0.982 | 0.106 | hein_WMM bioplex_WMM bioplex3_WMM WMM_only |
| VPS26A | ANKRD27 | 0.981 | 0.106 | hein_WMM bioplex_WMM bioplex3_WMM hein () |
| ANKRD27 | TBC1D5 | 0.945 | 0.082 | hein_WMM bioplex_WMM bioplex3_WMM WMM_only |
| VPS26A | TAS2R19 | 0.921 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| VPS35 | CFAP20DC | 0.917 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| VPS26B | FKBP15 | 0.876 | 0.04 | hein_WMM hein () |
| VPS26B | LRRC73 | 0.867 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| VPS26A | FKBP15 | 0.816 | 0.216 | hein_WMM hein () gupta_WMM |
| ANKRD27 | FKBP15 | 0.796 | 0.07 | hein_WMM WMM_only |
| VPS35 | FKBP15 | 0.617 | 0.112 | hein_WMM bioplex3_WMM gupta_WMM WMM_only |
| VPS29 | LRRC73 | 0.614 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| VPS35 | LRRC73 | 0.604 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| TBC1D5 | CFAP20DC | 0.415 | bioplex3_WMM WMM_only | |
| VPS26B | CFAP20DC | 0.254 | bioplex3_WMM WMM_only | |
| VPS26A | CFAP20DC | 0.25 | bioplex3_WMM WMM_only | |
| VPS35 | TAS2R19 | 0.119 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| VPS29 | CFAP20DC | 0.093 | bioplex3_WMM WMM_only | |
| VPS29 | TAS2R19 | 0.058 | bioplex3_HEK293 bioplex3_WMM WMM_only |
Related Complexes
| Genename | Complexes |
|---|---|
| CFAP20DC | huMAP3_13244.1 |
| FKBP15 | huMAP3_01515.1 huMAP3_10031.1 huMAP3_13244.1 |
| VPS26B | huMAP3_01277.1 huMAP3_13244.1 |
| VPS26A | huMAP3_01277.1 huMAP3_13244.1 |
| TBC1D5 | huMAP3_01277.1 huMAP3_13244.1 |
| VPS29 | huMAP3_01277.1 huMAP3_01290.1 huMAP3_07032.1 huMAP3_13244.1 huMAP3_14444.1 |
| ANKRD27 | huMAP3_01277.1 huMAP3_13244.1 huMAP3_14474.1 |
| VPS35 | huMAP3_01277.1 huMAP3_13244.1 |
| LRRC73 | huMAP3_04837.1 huMAP3_10926.1 huMAP3_13244.1 |
| TAS2R19 | huMAP3_12410.1 huMAP3_13244.1 huMAP3_13729.1 |