hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_13266.1
Complex Portal: CPX-16277
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| CIC | Protein capicua homolog | 5 | UniProt NCBI |
| ATXN1 | Ataxin-1 (Spinocerebellar ataxia type 1 protein) | 5 | UniProt NCBI |
| ATXN1L | Ataxin-1-like (Brother of ataxin-1) (Brother of ATXN1) | 5 | UniProt NCBI |
| ZBTB18 | Zinc finger and BTB domain-containing protein 18 (58 kDa repressor protein) (Transcriptional repressor RP58) (Translin-associated zinc finger protein 1) (TAZ-1) (Zinc finger protein 238) (Zinc finger protein C2H2-171) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:7236 | 5.12628525639e-06 | 0.5 | CIC ATXN1 | ARXN1-CIC complex |
| KEGG:05017 | 0.000108396031683 | 0.75 | CIC ATXN1L ATXN1 | Spinocerebellar ataxia |
| GO:0035176 | 0.000372255315939 | 0.75 | CIC ATXN1L ATXN1 | social behavior |
| GO:0051703 | 0.000510886175237 | 0.75 | CIC ATXN1L ATXN1 | biological process involved in intraspecies interaction between organisms |
| KEGG:04330 | 0.00281740883519 | 0.5 | ATXN1 ATXN1L | Notch signaling pathway |
| GO:0007612 | 0.00409056451107 | 0.75 | CIC ATXN1L ATXN1 | learning |
| GO:0007613 | 0.00582352741409 | 0.75 | CIC ATXN1L ATXN1 | memory |
| HP:5200018 | 0.036003514982 | 0.5 | CIC ZBTB18 | Abnormal movements of the upper extremities |
| GO:0007611 | 0.0449670283878 | 0.75 | CIC ATXN1L ATXN1 | learning or memory |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| CIC | ZBTB18 | 0.999 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | ||
| ZBTB18 | ATXN1L | 0.998 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | ||
| CIC | ATXN1 | 0.892 | 0.25 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| CIC | ATXN1L | 0.883 | 0.19 | bioplex_WMM bioplex3_WMM WMM_only | |
| ATXN1L | ATXN1 | 0.325 | 0.104 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes