hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_13274.1
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| SCN2B | Sodium channel subunit beta-2 | 5 | UniProt NCBI |
| TBC1D23 | TBC1 domain family member 23 (HCV non-structural protein 4A-transactivated protein 1) | 5 | UniProt NCBI |
| RNF213 | E3 ubiquitin-protein ligase RNF213 (EC 2.3.2.27) (EC 3.6.4.-) (ALK lymphoma oligomerization partner on chromosome 17) (E3 ubiquitin-lipopolysaccharide ligase RNF213) (EC 2.3.2.-) (Mysterin) (RING finger protein 213) | 5 | UniProt NCBI |
| KNTC1 | Kinetochore-associated protein 1 (Rough deal homolog) (HsROD) (Rod) (hRod) | 5 | UniProt NCBI |
| FAM174A | Membrane protein FAM174A (Hepatitis C virus NS5A-transactivated protein 6) (HCV NS5A-transactivated protein 6) (Transmembrane protein 157) | 5 | UniProt NCBI |
| NF1 | Neurofibromin (Neurofibromatosis-related protein NF-1) [Cleaved into: Neurofibromin truncated] | 5 | UniProt NCBI |
| FAM118B | Protein FAM118B | 4 | UniProt NCBI |
| GSDME | Gasdermin-E (Inversely correlated with estrogen receptor expression 1) (ICERE-1) (Non-syndromic hearing impairment protein 5) [Cleaved into: Gasdermin-E, N-terminal (GSDME-NT); Gasdermin-E, C-terminal (GSDME-CT)] | 5 | UniProt NCBI |
| TMEM168 | Transmembrane protein 168 | 4 | UniProt NCBI |
| CPQ | Carboxypeptidase Q (EC 3.4.17.-) (Lysosomal dipeptidase) (Plasma glutamate carboxypeptidase) | 5 | UniProt NCBI |
| PLAA | Phospholipase A-2-activating protein (PLA2P) (PLAP) | 5 | UniProt NCBI |
| MARS1 | Methionine--tRNA ligase, cytoplasmic (EC 6.1.1.10) (Methionyl-tRNA synthetase) (MetRS) | 5 | UniProt NCBI |
| SLC39A13 | Zinc transporter ZIP13 (LIV-1 subfamily of ZIP zinc transporter 9) (LZT-Hs9) (Solute carrier family 39 member 13) (Zrt- and Irt-like protein 13) (ZIP-13) | 5 | UniProt NCBI |
| JTB | Protein JTB (Jumping translocation breakpoint protein) (Prostate androgen-regulated protein) (PAR protein) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HPA:0351181 | 0.0180071283547 | 0.857142857143 | KNTC1 MARS1 CPQ TBC1D23 RNF213 FAM118B FAM174A SLC39A13 JTB PLAA GSDME TMEM168 | pancreas; pancreatic endocrine cells[>=Low] |
| CORUM:6333 | 0.0499958217778 | 0.0714285714286 | SCN2B | Nav1.2-beta2 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD |
|---|---|---|---|
| FAM174A | TMEM168 | 0.999 | 0.09 |
| FAM174A | FAM118B | 0.996 | 0.162 |
| FAM174A | SLC39A13 | 0.994 | |
| FAM174A | GSDME | 0.991 | 0.154 |
| FAM174A | TBC1D23 | 0.989 | 0.156 |
| SLC39A13 | JTB | 0.987 | |
| FAM174A | CPQ | 0.983 | 0.126 |
| FAM118B | SCN2B | 0.978 | |
| RNF213 | SCN2B | 0.963 | |
| KNTC1 | GSDME | 0.961 | 0.114 |
| GSDME | RNF213 | 0.954 | 0.064 |
| GSDME | PLAA | 0.942 | 0.044 |
| FAM118B | RNF213 | 0.914 | 0.105 |
| FAM174A | PLAA | 0.913 | 0.195714285714 |
| TMEM168 | SLC39A13 | 0.892 | |
| NF1 | PLAA | 0.883 | 0.13 |
| FAM174A | RNF213 | 0.875 | 0.118482758621 |
| MARS1 | FAM118B | 0.868 | 0.056 |
| KNTC1 | RNF213 | 0.866 | 0.08 |
| KNTC1 | PLAA | 0.864 | 0.312 |
| FAM174A | MARS1 | 0.861 | 0.078 |
| KNTC1 | SCN2B | 0.859 | |
| MARS1 | GSDME | 0.831 | 0.066 |
| NF1 | RNF213 | 0.826 | 0.088 |
| GSDME | SCN2B | 0.816 | |
| KNTC1 | NF1 | 0.803 | 0.094 |
| TMEM168 | PLAA | 0.677 | 0.052 |
| TBC1D23 | SLC39A13 | 0.675 | |
| SLC39A13 | FAM118B | 0.675 | |
| TBC1D23 | TMEM168 | 0.675 | 0.064 |
| RNF213 | PLAA | 0.653 | 0.244 |
| TMEM168 | FAM118B | 0.631 | 0.062 |
| GSDME | FAM118B | 0.624 | 0.034 |
| SCN2B | PLAA | 0.507 | |
| KNTC1 | MARS1 | 0.455 | 0.168 |
| MARS1 | PLAA | 0.439 | 0.086 |
| NF1 | GSDME | 0.416 | 0.036 |
| MARS1 | RNF213 | 0.414 | 0.22 |
| SLC39A13 | PLAA | 0.405 | |
| SLC39A13 | GSDME | 0.388 | |
| TMEM168 | GSDME | 0.356 | 0.024 |
| FAM118B | PLAA | 0.346 | 0.08 |
| FAM174A | NF1 | 0.335 | 0.25 |
| SLC39A13 | RNF213 | 0.326 | |
| MARS1 | TMEM168 | 0.323 | 0.07 |
| TMEM168 | NF1 | 0.32 | 0.07 |
| MARS1 | SLC39A13 | 0.285 | |
| TBC1D23 | GSDME | 0.267 | 0.038 |
| MARS1 | SCN2B | 0.266 | |
| TBC1D23 | FAM118B | 0.249 | 0.032 |
| TBC1D23 | RNF213 | 0.175 | 0.104 |
| TBC1D23 | PLAA | 0.172 | 0.05 |
| TMEM168 | RNF213 | 0.147 | 0.0744827586207 |
| KNTC1 | FAM118B | 0.104 | 0.036 |
| NF1 | FAM118B | 0.103 | 0.056 |
| JTB | PLAA | 0.1 | 0.054 |
| NF1 | SCN2B | 0.084 | |
| NF1 | JTB | 0.077 | 0.06 |
| NF1 | SLC39A13 | 0.072 | |
| TBC1D23 | NF1 | 0.024 | 0.042 |
| MARS1 | NF1 | 0.021 | 0.092 |
| CPQ | MARS1 | 0.021 | 0.062 |
| MARS1 | JTB | 0.016 | 0.11 |
| TBC1D23 | MARS1 | 0.014 | 0.024 |
Related Complexes