hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_13280.1
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| SLC11A2 | Natural resistance-associated macrophage protein 2 (NRAMP 2) (Divalent cation transporter 1) (Divalent metal transporter 1) (DMT-1) (Solute carrier family 11 member 2) | 5 | UniProt NCBI |
| G6PC3 | Glucose-6-phosphatase 3 (G-6-Pase 3) (G6Pase 3) (EC 3.1.3.9) (Glucose-6-phosphatase beta) (G6Pase-beta) (Ubiquitous glucose-6-phosphatase catalytic subunit-related protein) | 5 | UniProt NCBI |
| SLC52A2 | Solute carrier family 52, riboflavin transporter, member 2 (Porcine endogenous retrovirus A receptor 1) (PERV-A receptor 1) (Protein GPR172A) (Riboflavin transporter 3) (hRFT3) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HP:0012131 | 0.0142438401108 | 0.666666666667 | G6PC3 SLC11A2 | Abnormal number of erythroid precursors |
| WP:WP5189 | 0.0331010360575 | 0.333333333333 | SLC11A2 | Copper metabolism |
| REAC:R-HSA-5619048 | 0.0498224659464 | 0.333333333333 | SLC11A2 | Defective SLC11A2 causes hypochromic microcytic anemia, with iron overload 1 (AHMIO1) |
| REAC:R-HSA-3282872 | 0.0498224659464 | 0.333333333333 | G6PC3 | Severe congenital neutropenia type 4 (G6PC3) |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| G6PC3 | SLC11A2 | 0.904 | bioplex3_WMM WMM_only | |
| G6PC3 | SLC52A2 | 0.904 | 0.118 | bioplex3_WMM WMM_only |
| SLC52A2 | SLC11A2 | 0.902 | bioplex3_WMM WMM_only |
Related Complexes