hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_13290.1
Complex Portal: CPX-13656
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| VEGFB | Vascular endothelial growth factor B (VEGF-B) (VEGF-related factor) (VRF) | 5 | UniProt NCBI |
| VEGFA | Vascular endothelial growth factor A, long form (L-VEGF) (Vascular permeability factor) (VPF) [Cleaved into: N-VEGF; VEGFA] | 5 | UniProt NCBI |
| FLT1 | Vascular endothelial growth factor receptor 1 (VEGFR-1) (EC 2.7.10.1) (Fms-like tyrosine kinase 1) (FLT-1) (Tyrosine-protein kinase FRT) (Tyrosine-protein kinase receptor FLT) (FLT) (Vascular permeability factor receptor) | 5 | UniProt NCBI |
| GBGT1 | Globoside alpha-1,3-N-acetylgalactosaminyltransferase 1 (EC 2.4.1.-) (Forssman glycolipid synthase-like protein) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:00603 | 0.0308726352593 | 0.5 | GBGT1 | Glycosphingolipid biosynthesis - globo and isoglobo series |
| WP:WP3593 | 0.0373151717536 | 0.5 | VEGFB | MicroRNA for targeting cancer growth and vascularization in glioblastoma |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| VEGFA | FLT1 | 0.992 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| VEGFB | VEGFA | 0.968 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| FLT1 | GBGT1 | 0.955 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| VEGFB | FLT1 | 0.164 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes
| Genename | Complexes |
|---|---|
| VEGFB | huMAP3_01715.1 huMAP3_06306.1 huMAP3_08266.1 huMAP3_13290.1 |
| VEGFA | huMAP3_01715.1 huMAP3_05179.1 huMAP3_13290.1 |
| FLT1 | huMAP3_05179.1 huMAP3_13290.1 |
| GBGT1 | huMAP3_05179.1 huMAP3_13290.1 |