hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_13296.1
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| TLR6 | Toll-like receptor 6 (CD antigen CD286) | 5 | UniProt NCBI |
| OR1E1 | Olfactory receptor 1E1 (Olfactory receptor 13-66) (OR13-66) (Olfactory receptor 17-2/17-32) (OR17-2) (OR17-32) (Olfactory receptor 1E5) (Olfactory receptor 1E6) (Olfactory receptor 5-85) (OR5-85) (Olfactory receptor OR17-18) (Olfactory receptor-like protein HGMP07I) | 4 | UniProt NCBI |
| MUCL1 | Mucin-like protein 1 (Protein BS106) (Small breast epithelial mucin) | 5 | UniProt NCBI |
| TLR1 | Toll-like receptor 1 (Toll/interleukin-1 receptor-like protein) (TIL) (CD antigen CD281) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP3877 | 0.000267833349503 | 0.5 | TLR6 TLR1 | MYD88 distinct input output pathway |
| WP:WP3858 | 0.000894348084449 | 0.5 | TLR6 TLR1 | Toll like receptor signaling related to MyD88 |
| REAC:R-HSA-5602498 | 0.000931962666506 | 0.5 | TLR6 TLR1 | MyD88 deficiency (TLR2/4) |
| REAC:R-HSA-5603041 | 0.000931962666506 | 0.5 | TLR6 TLR1 | IRAK4 deficiency (TLR2/4) |
| REAC:R-HSA-5686938 | 0.00107524337392 | 0.5 | TLR6 TLR1 | Regulation of TLR by endogenous ligand |
| REAC:R-HSA-5602358 | 0.00359044851421 | 0.5 | TLR6 TLR1 | Diseases associated with the TLR signaling cascade |
| REAC:R-HSA-5260271 | 0.00359044851421 | 0.5 | TLR6 TLR1 | Diseases of Immune System |
| GO:0070340 | 0.00842684400117 | 0.5 | TLR6 TLR1 | detection of bacterial lipopeptide |
| WP:WP75 | 0.00862655865142 | 0.5 | TLR6 TLR1 | Toll like receptor signaling pathway |
| KEGG:04620 | 0.00931062778609 | 0.5 | TLR6 TLR1 | Toll-like receptor signaling pathway |
| GO:0042494 | 0.0168521501606 | 0.5 | TLR6 TLR1 | detection of bacterial lipoprotein |
| GO:0035663 | 0.0168521501606 | 0.5 | TLR6 TLR1 | Toll-like receptor 2 binding |
| KEGG:05152 | 0.02620193588 | 0.5 | TLR6 TLR1 | Tuberculosis |
| REAC:R-HSA-1236974 | 0.0363250695065 | 0.5 | TLR6 TLR1 | ER-Phagosome pathway |
| REAC:R-HSA-166058 | 0.0453901932463 | 0.5 | TLR6 TLR1 | MyD88:MAL(TIRAP) cascade initiated on plasma membrane |
| REAC:R-HSA-168188 | 0.0453901932463 | 0.5 | TLR6 TLR1 | Toll Like Receptor TLR6:TLR2 Cascade |
| REAC:R-HSA-181438 | 0.0473231872721 | 0.5 | TLR6 TLR1 | Toll Like Receptor 2 (TLR2) Cascade |
| REAC:R-HSA-168179 | 0.0473231872721 | 0.5 | TLR6 TLR1 | Toll Like Receptor TLR1:TLR2 Cascade |
| REAC:R-HSA-1236975 | 0.0483046623758 | 0.5 | TLR6 TLR1 | Antigen processing-Cross presentation |
| CORUM:7048 | 0.049938562206 | 0.25 | TLR1 | TLR1-TLR2 complex |
| CORUM:7049 | 0.049938562206 | 0.25 | TLR1 | TLR1-TLR2-lipoprotein complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| TLR6 | TLR1 | 0.995 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| MUCL1 | TLR1 | 0.81 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| MUCL1 | OR1E1 | 0.81 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| MUCL1 | TLR6 | 0.076 | bioplex3_WMM WMM_only |
Related Complexes