hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_13313.1
Complex Portal: CPX-14585
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| PURG | Purine-rich element-binding protein gamma (Purine-rich element-binding protein G) | 4 | UniProt NCBI |
| HELZ2 | 3'-5' exoribonuclease HELZ2 (EC 3.1.13.1) (ATP-dependent RNA helicase PRIC285) (EC 3.6.4.13) (Helicase with zinc finger 2, transcriptional coactivator) (Helicase with zinc finger domain 2) (PPAR-alpha-interacting complex protein 285) (PPAR-gamma DNA-binding domain-interacting protein 1) (PDIP1) (PPAR-gamma DBD-interacting protein 1) (Peroxisomal proliferator-activated receptor A-interacting complex 285 kDa protein) | 5 | UniProt NCBI |
| NFX1 | Transcriptional repressor NF-X1 (EC 2.3.2.-) (Nuclear transcription factor, X box-binding protein 1) | 5 | UniProt NCBI |
| ZNF420 | Zinc finger protein 420 | 4 | UniProt NCBI |
| CEP85 | Centrosomal protein of 85 kDa (Cep85) (Coiled-coil domain-containing protein 21) | 5 | UniProt NCBI |
| MAP3K1 | Mitogen-activated protein kinase kinase kinase 1 (EC 2.7.11.25) (MAPK/ERK kinase kinase 1) (MEK kinase 1) (MEKK 1) (EC 2.3.2.27) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP314 | 0.00703705758996 | 0.333333333333 | NFX1 MAP3K1 | Fas ligand pathway and stress induction of heat shock proteins |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| PURG | MAP3K1 | 0.986 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| HELZ2 | PURG | 0.986 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| PURG | ZNF420 | 0.969 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| NFX1 | PURG | 0.939 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| CEP85 | MAP3K1 | 0.846 | 0.198 | hein_WMM hein () | |
| ZNF420 | MAP3K1 | 0.274 | bioplex3_WMM WMM_only | ||
| NFX1 | MAP3K1 | 0.113 | 0.122 | bioplex3_WMM WMM_only | |
| NFX1 | HELZ2 | 0.102 | 0.142 | bioplex3_WMM WMM_only | |
| NFX1 | ZNF420 | 0.095 | bioplex3_WMM WMM_only | ||
| HELZ2 | MAP3K1 | 0.076 | 0.096 | bioplex3_WMM WMM_only | |
| HELZ2 | ZNF420 | 0.076 | bioplex3_WMM WMM_only | ||
| NFX1 | CEP85 | 0.005 | 0.134 | youn_WMM gupta_WMM WMM_only |
Related Complexes