hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_13328.1
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| IL1RL2 | Interleukin-1 receptor-like 2 (EC 3.2.2.6) (IL-36 receptor) (IL-36R) (Interleukin-1 receptor-related protein 2) (IL-1Rrp2) (IL1R-rp2) | 5 | UniProt NCBI |
| POTEI | POTE ankyrin domain family member I | 4 | UniProt NCBI |
| NDUFA4L2 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4-like 2 (NADH-ubiquinone oxidoreductase MLRQ subunit homolog) (NUOMS) | 2 | UniProt NCBI |
| LRRC20 | Leucine-rich repeat-containing protein 20 | 2 | UniProt NCBI |
| ABRA | Actin-binding Rho-activating protein (Striated muscle activator of Rho-dependent signaling) (STARS) | 3 | UniProt NCBI |
| ACTC1 | Actin, alpha cardiac muscle 1 (EC 3.6.4.-) (Alpha-cardiac actin) [Cleaved into: Actin, alpha cardiac muscle 1, intermediate form] | 5 | UniProt NCBI |
| ACTA2 | Actin, aortic smooth muscle (EC 3.6.4.-) (Alpha-actin-2) (Cell growth-inhibiting gene 46 protein) [Cleaved into: Actin, aortic smooth muscle, intermediate form] | 5 | UniProt NCBI |
| PHACTR2 | Phosphatase and actin regulator 2 | 5 | UniProt NCBI |
| ANXA11 | Annexin A11 (56 kDa autoantigen) (Annexin XI) (Annexin-11) (Calcyclin-associated annexin 50) (CAP-50) | 5 | UniProt NCBI |
| CAP1 | Adenylyl cyclase-associated protein 1 (CAP 1) | 5 | UniProt NCBI |
| VENTX | Homeobox protein VENTX (VENT homeobox homolog) (VENT-like homeobox protein 2) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP383 | 0.0315566226681 | 0.181818181818 | ACTC1 ACTA2 | Striated muscle contraction pathway |
| WP:WP4534 | 0.0412834882198 | 0.181818181818 | ACTC1 ACTA2 | Mechanoregulation and pathology of YAP TAZ via Hippo and non Hippo mechanisms |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| ACTA2 | CAP1 | 0.997 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 gupta_WMM boldt_WMM | |
| ACTA2 | PHACTR2 | 0.959 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| LRRC20 | ACTA2 | 0.958 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only | |
| PHACTR2 | POTEI | 0.949 | 0.124 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| IL1RL2 | POTEI | 0.915 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| ACTA2 | ABRA | 0.911 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 gupta_WMM WMM_only | |
| CAP1 | POTEI | 0.902 | 0.281 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| ABRA | POTEI | 0.88 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| POTEI | NDUFA4L2 | 0.878 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| ACTA2 | ANXA11 | 0.859 | hein_WMM bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only | |
| ACTC1 | PHACTR2 | 0.851 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| LRRC20 | POTEI | 0.822 | 0.062 | bioplex3_HEK293 bioplex3_WMM WMM_only |
| ACTA2 | VENTX | 0.816 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| LRRC20 | ACTC1 | 0.735 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| ACTC1 | ABRA | 0.621 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| ACTA2 | ACTC1 | 0.449 | bioplex_WMM bioplex3_WMM gupta_WMM WMM_only boldt_WMM | |
| ACTC1 | POTEI | 0.449 | bioplex_WMM bioplex3_WMM WMM_only | |
| ACTC1 | IL1RL2 | 0.416 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| ACTC1 | NDUFA4L2 | 0.416 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| ACTC1 | CAP1 | 0.342 | bioplex_WMM bioplex3_WMM WMM_only | |
| ACTA2 | POTEI | 0.338 | bioplex_WMM bioplex3_WMM WMM_only | |
| CAP1 | PHACTR2 | 0.209 | 0.164 | bioplex_WMM bioplex3_WMM WMM_only |
| CAP1 | IL1RL2 | 0.131 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| POTEI | ANXA11 | 0.032 | 0.054 | bioplex_WMM bioplex3_WMM WMM_only |
| CAP1 | NDUFA4L2 | 0.032 | bioplex3_HEK293 bioplex () | |
| ACTC1 | ANXA11 | 0.024 | bioplex_WMM bioplex3_WMM WMM_only | |
| ANXA11 | NDUFA4L2 | 0.018 | bioplex3_HEK293 bioplex () | |
| IL1RL2 | ANXA11 | 0.008 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| LRRC20 | ANXA11 | 0.007 | 0.022 | bioplex3_HEK293 bioplex3_WMM WMM_only |
| ACTC1 | VENTX | 0.005 | bioplex3_HEK293 bioplex () | |
| ABRA | ANXA11 | 0.004 | bioplex3_HCT116 WMM_only | |
| ANXA11 | VENTX | 0.003 | bioplex3_HEK293 bioplex () bioplex3_HCT116 | |
| LRRC20 | CAP1 | 0.002 | 0.054 | bioplex3_HCT116 WMM_only |
| CAP1 | VENTX | 0.002 | bioplex3_HCT116 WMM_only | |
| CAP1 | ANXA11 | 0.002 | 0.248 | bioplex_WMM bioplex3_WMM gupta_WMM fraction treiber_WMM |
Related Complexes