hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_13351.1
Confidence: Medium  
ProteinsGenename | Protein Name | Uniprot Annotation Score | Links |
---|---|---|---|
SH2D1B | SH2 domain-containing protein 1B (EWS/FLI1-activated transcript 2) (EAT-2) | 5 | UniProt   NCBI |
ROR1 | Inactive tyrosine-protein kinase transmembrane receptor ROR1 (Neurotrophic tyrosine kinase, receptor-related 1) | 5 | UniProt   NCBI |
SIRPA | Tyrosine-protein phosphatase non-receptor type substrate 1 (SHP substrate 1) (SHPS-1) (Brain Ig-like molecule with tyrosine-based activation motifs) (Bit) (CD172 antigen-like family member A) (Inhibitory receptor SHPS-1) (Macrophage fusion receptor) (MyD-1 antigen) (Signal-regulatory protein alpha-1) (Sirp-alpha-1) (Signal-regulatory protein alpha-2) (Sirp-alpha-2) (Signal-regulatory protein alpha-3) (Sirp-alpha-3) (p84) (CD antigen CD172a) | 5 | UniProt   NCBI |
SIRPB1 | Signal-regulatory protein beta-1 isoform 3 (SIRP-beta-1 isoform 3) | 4 | UniProt   NCBI |
SIRPG | Signal-regulatory protein gamma (SIRP-gamma) (CD172 antigen-like family member B) (Signal-regulatory protein beta-2) (SIRP-b2) (SIRP-beta-2) (CD antigen CD172g) | 5 | UniProt   NCBI |
Enrichments
Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
---|---|---|---|---|
  REAC:R-HSA-391160 | 5.14505990951e-07 | 0.6 | SIRPA SIRPG SIRPB1 | Signal regulatory protein family interactions |
  KEGG:04380 | 0.000227771705542 | 0.6 | SIRPA SIRPG SIRPB1 | Osteoclast differentiation |
  KEGG:04148 | 0.00028582601872 | 0.6 | SIRPA SIRPG SIRPB1 | Efferocytosis |
  REAC:R-HSA-1500931 | 0.000546262833483 | 0.6 | SIRPA SIRPG SIRPB1 | Cell-Cell communication |
  GO:0050766 | 0.0211358171848 | 0.6 | SIRPA SIRPG SIRPB1 | positive regulation of phagocytosis |
  WP:WP4673 | 0.0399620586052 | 0.4 | SIRPA SIRPG | Male infertility |
Edges
Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
---|---|---|---|---|
 SIRPG |  SIRPA | 0.991 | 0.166           | bioplex3_HEK293     bioplex ()     bioplex_WMM     bioplex3_WMM     |
 SIRPA |  SIRPB1 | 0.99 | 0.382           | bioplex3_HEK293     bioplex3_WMM     WMM_only     |
 SIRPA |  SH2D1B | 0.981 |            | bioplex3_HEK293     bioplex3_WMM     WMM_only     |
 ROR1 |  SIRPA | 0.905 | 0.096           | bioplex3_WMM     WMM_only     |
Related Complexes