hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_13363.1
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| RAC1 | Ras-related C3 botulinum toxin substrate 1 (EC 3.6.5.2) (Cell migration-inducing gene 5 protein) (Ras-like protein TC25) (p21-Rac1) | 5 | UniProt NCBI |
| IL18 | Interleukin-18 (IL-18) (Iboctadekin) (Interferon gamma-inducing factor) (IFN-gamma-inducing factor) (Interleukin-1 gamma) (IL-1 gamma) | 5 | UniProt NCBI |
| CRIPTO | Protein Cripto (Cripto, EGF-CFC family member) (Cripto-1 growth factor) (CRGF) (Epidermal growth factor-like cripto protein CR1) (Teratocarcinoma-derived growth factor 1) | 5 | UniProt NCBI |
| EGR3 | Early growth response protein 3 (EGR-3) (Zinc finger protein pilot) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP1433 | 0.000367738611184 | 0.666666666667 | RAC1 IL18 | Nucleotide binding oligomerization domain NOD pathway |
| KEGG:05135 | 0.00497809897987 | 0.666666666667 | RAC1 IL18 | Yersinia infection |
| KEGG:05130 | 0.0102516009655 | 0.666666666667 | RAC1 IL18 | Pathogenic Escherichia coli infection |
| KEGG:05417 | 0.0121980359765 | 0.666666666667 | RAC1 IL18 | Lipid and atherosclerosis |
| KEGG:05203 | 0.013023543882 | 0.666666666667 | RAC1 EGR3 | Viral carcinogenesis |
| WP:WP5115 | 0.0163374881119 | 0.666666666667 | RAC1 IL18 | Network map of SARS CoV 2 signaling pathway |
| KEGG:05132 | 0.0188728482722 | 0.666666666667 | RAC1 IL18 | Salmonella infection |
| KEGG:05131 | 0.0193802248568 | 0.666666666667 | RAC1 IL18 | Shigellosis |
| WP:WP3943 | 0.0331010360575 | 0.333333333333 | RAC1 | Robo4 and VEGF signaling pathways crosstalk |
| REAC:R-HSA-166520 | 0.0436932800731 | 0.666666666667 | RAC1 EGR3 | Signaling by NTRKs |
| CORUM:3011 | 0.0499402709677 | 0.333333333333 | RAC1 | APC-IQGAP1-Rac1 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| RAC1 | CRIPTO | 0.991 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| IL18 | EGR3 | 0.952 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| CRIPTO | IL18 | 0.835 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| RAC1 | IL18 | 0.377 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| RAC1 | EGR3 | 0.005 | bioplex3_HCT116 WMM_only |
Related Complexes
| Genename | Complexes |
|---|---|
| RAC1 | huMAP3_02074.1 huMAP3_04665.1 huMAP3_10215.1 huMAP3_13363.1 |
| IL18 | huMAP3_04787.1 huMAP3_13363.1 |
| CRIPTO | huMAP3_02074.1 huMAP3_03100.1 huMAP3_05775.1 huMAP3_08787.1 huMAP3_09818.1 huMAP3_10711.1 huMAP3_12700.1 huMAP3_13363.1 |
| EGR3 | huMAP3_04787.1 huMAP3_13363.1 |