hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_13366.1
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| PTPN9 | Tyrosine-protein phosphatase non-receptor type 9 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG2) (PTPase MEG2) | 5 | UniProt NCBI |
| MTMR12 | Myotubularin-related protein 12 (Inactive phosphatidylinositol 3-phosphatase 12) (Phosphatidylinositol 3 phosphate 3-phosphatase adapter subunit) (3-PAP) (3-phosphatase adapter protein) | 5 | UniProt NCBI |
| MTM1 | Myotubularin (Phosphatidylinositol-3,5-bisphosphate 3-phosphatase) (EC 3.1.3.95) (Phosphatidylinositol-3-phosphate phosphatase) (EC 3.1.3.64) | 5 | UniProt NCBI |
| CGA | Glycoprotein hormones alpha chain (Anterior pituitary glycoprotein hormones common subunit alpha) (Choriogonadotropin alpha chain) (Chorionic gonadotrophin subunit alpha) (CG-alpha) (Follicle-stimulating hormone alpha chain) (FSH-alpha) (Follitropin alpha chain) (Luteinizing hormone alpha chain) (LSH-alpha) (Lutropin alpha chain) (Thyroid-stimulating hormone alpha chain) (TSH-alpha) (Thyrotropin alpha chain) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-1660516 | 0.00107524337392 | 0.5 | MTMR12 MTM1 | Synthesis of PIPs at the early endosome membrane |
| WP:WP4971 | 0.002190823719 | 0.5 | MTMR12 MTM1 | Phosphoinositides metabolism |
| REAC:R-HSA-1483255 | 0.0260384914588 | 0.5 | MTMR12 MTM1 | PI Metabolism |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| PTPN9 | MTM1 | 0.983 | 0.074 | bioplex3_HEK293 bioplex3_WMM WMM_only |
| CGA | MTMR12 | 0.962 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| MTM1 | CGA | 0.962 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| MTM1 | MTMR12 | 0.16 | 0.158 | bioplex3_WMM fraction |
Related Complexes