hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_13373.1
Complex Portal: CPX-14084
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| CPA5 | Carboxypeptidase A5 (EC 3.4.17.-) | 4 | UniProt NCBI |
| EPHA4 | Ephrin type-A receptor 4 (EC 2.7.10.1) (EPH-like kinase 8) (EK8) (hEK8) (Tyrosine-protein kinase TYRO1) (Tyrosine-protein kinase receptor SEK) | 5 | UniProt NCBI |
| FOXF1 | Forkhead box protein F1 (Forkhead-related activator 1) (FREAC-1) (Forkhead-related protein FKHL5) (Forkhead-related transcription factor 1) | 5 | UniProt NCBI |
| CYP1A2 | Cytochrome P450 1A2 (EC 1.14.14.1) (CYPIA2) (Cholesterol 25-hydroxylase) (Cytochrome P(3)450) (Cytochrome P450 4) (Cytochrome P450-P3) (Hydroperoxy icosatetraenoate dehydratase) (EC 4.2.1.152) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP2646 | 0.0248784837172 | 0.25 | CYP1A2 | Lidocaine metabolism |
| WP:WP2542 | 0.049746753544 | 0.25 | CYP1A2 | Sulindac metabolic pathway |
| WP:WP3633 | 0.049746753544 | 0.25 | CYP1A2 | Caffeine and theobromine metabolism |
| WP:WP694 | 0.049746753544 | 0.25 | CYP1A2 | Arylamine metabolism |
| REAC:R-HSA-211957 | 0.0499436884912 | 0.25 | CYP1A2 | Aromatic amines can be N-hydroxylated or N-dealkylated by CYP1A2 |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| CPA5 | EPHA4 | 0.952 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| CYP1A2 | EPHA4 | 0.935 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| FOXF1 | CPA5 | 0.865 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| FOXF1 | EPHA4 | 0.057 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes