hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_13421.1
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| THAP2 | THAP domain-containing protein 2 | 2 | UniProt NCBI |
| TET2 | Methylcytosine dioxygenase TET2 (EC 1.14.11.80) | 5 | UniProt NCBI |
| HCFC1 | Host cell factor 1 (HCF) (HCF-1) (C1 factor) (CFF) (VCAF) (VP16 accessory protein) [Cleaved into: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N-terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C-terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6] | 5 | UniProt NCBI |
| HCFC1R1 | Host cell factor C1 regulator 1 (HCF-1 beta-propeller-interacting protein) | 4 | UniProt NCBI |
| OGT | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit (EC 2.4.1.255) (O-GlcNAc transferase subunit p110) (O-linked N-acetylglucosamine transferase 110 kDa subunit) (OGT) | 5 | UniProt NCBI |
| THAP6 | THAP domain-containing protein 6 | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:7354 | 5.12534978153e-05 | 0.333333333333 | HCFC1 OGT | ASXL1-HCFC1-OGT complex |
| CORUM:6462 | 0.000477929626316 | 0.333333333333 | HCFC1 OGT | MLL1 complex |
| CORUM:7221 | 0.000614368794823 | 0.333333333333 | HCFC1 OGT | NSL complex |
| CORUM:6460 | 0.000767820823501 | 0.333333333333 | HCFC1 OGT | MLL2 complex |
| CORUM:6469 | 0.000767820823501 | 0.333333333333 | HCFC1 OGT | Set1A complex |
| CORUM:6470 | 0.00112572613738 | 0.333333333333 | HCFC1 OGT | Set1B complex |
| CORUM:2721 | 0.00204528068441 | 0.333333333333 | HCFC1 OGT | HCF-1 complex |
| REAC:R-HSA-212165 | 0.00563868631148 | 0.5 | HCFC1 TET2 OGT | Epigenetic regulation of gene expression |
| REAC:R-HSA-9772755 | 0.0200002568185 | 0.333333333333 | HCFC1 OGT | Formation of WDR5-containing histone-modifying complexes |
| KEGG:03083 | 0.0232178892038 | 0.333333333333 | HCFC1 OGT | Polycomb repressive complex |
| HPA:0320851 | 0.0276657994521 | 0.666666666667 | THAP2 HCFC1R1 OGT HCFC1 | nasopharynx; ciliated cells (cell body)[>=Low] |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| HCFC1 | OGT | 0.993 | 0.098 | hein_WMM bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only boldt_WMM |
| HCFC1 | THAP6 | 0.987 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| OGT | THAP6 | 0.985 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| HCFC1 | HCFC1R1 | 0.967 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| TET2 | OGT | 0.963 | 0.146 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM |
| HCFC1R1 | OGT | 0.958 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| OGT | THAP2 | 0.954 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| HCFC1 | THAP2 | 0.905 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| HCFC1 | TET2 | 0.006 | 0.134 | bioplex3_HEK293 bioplex () bioplex3_WMM youn_WMM |
Related Complexes