hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_13428.1
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| PITX1 | Pituitary homeobox 1 (Hindlimb-expressed homeobox protein backfoot) (Homeobox protein PITX1) (Paired-like homeodomain transcription factor 1) | 5 | UniProt NCBI |
| FGF11 | Fibroblast growth factor 11 (FGF-11) (Fibroblast growth factor homologous factor 3) (FHF-3) | 4 | UniProt NCBI |
| CREB3L3 | Cyclic AMP-responsive element-binding protein 3-like protein 3 (cAMP-responsive element-binding protein 3-like protein 3) (Transcription factor CREB-H) [Cleaved into: Processed cyclic AMP-responsive element-binding protein 3-like protein 3] | 5 | UniProt NCBI |
| FAM13C | Protein FAM13C | 5 | UniProt NCBI |
| AHCYL1 | S-adenosylhomocysteine hydrolase-like protein 1 (DC-expressed AHCY-like molecule) (IP(3)Rs binding protein released with IP(3)) (IRBIT) (Putative adenosylhomocysteinase 2) (S-adenosyl-L-homocysteine hydrolase 2) (AdoHcyase 2) | 5 | UniProt NCBI |
| CHD9 | Chromodomain-helicase-DNA-binding protein 9 (CHD-9) (EC 3.6.4.12) (ATP-dependent helicase CHD9) (Chromatin-related mesenchymal modulator) (CReMM) (Chromatin-remodeling factor CHROM1) (Kismet homolog 2) (PPAR-alpha-interacting complex protein 320 kDa) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) | 5 | UniProt NCBI |
| AHCYL2 | Adenosylhomocysteinase 3 (AdoHcyase 3) (EC 3.13.2.1) (IP(3)Rs binding protein released with IP(3) 2) (IRBIT2) (Long-IRBIT) (S-adenosyl-L-homocysteine hydrolase 3) (S-adenosylhomocysteine hydrolase-like protein 2) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:00270 | 0.0105163416614 | 0.285714285714 | AHCYL2 AHCYL1 | Cysteine and methionine metabolism |
| WP:WP2525 | 0.0261327164033 | 0.285714285714 | AHCYL2 AHCYL1 | Trans sulfuration one carbon metabolism and related pathways |
| GO:0033353 | 0.0294899169624 | 0.285714285714 | AHCYL2 AHCYL1 | S-adenosylmethionine cycle |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| AHCYL1 | AHCYL2 | 0.999 | 0.236 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt youn_WMM bioplex3_HCT116 gupta_WMM boldt_WMM |
| FAM13C | AHCYL2 | 0.986 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| AHCYL2 | CREB3L3 | 0.971 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| AHCYL1 | PITX1 | 0.947 | 0.106 | bioplex3_WMM bioplex3_HCT116 WMM_only |
| AHCYL1 | CREB3L3 | 0.942 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| AHCYL1 | FAM13C | 0.939 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| AHCYL2 | PITX1 | 0.927 | 0.104 | bioplex3_WMM bioplex3_HCT116 WMM_only |
| AHCYL2 | FGF11 | 0.89 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| AHCYL1 | FGF11 | 0.889 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| CHD9 | FGF11 | 0.881 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| CHD9 | AHCYL1 | 0.262 | 0.158 | bioplex_WMM bioplex3_WMM fraction |
| CHD9 | AHCYL2 | 0.229 | 0.102 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only |
Related Complexes