hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_13443.1
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| PROSER1 | Proline and serine-rich protein 1 | 4 | UniProt NCBI |
| PSPC1 | Paraspeckle component 1 (Paraspeckle protein 1) | 5 | UniProt NCBI |
| ORC6 | Origin recognition complex subunit 6 | 5 | UniProt NCBI |
| NONO | Non-POU domain-containing octamer-binding protein (NonO protein) (54 kDa nuclear RNA- and DNA-binding protein) (p54(nrb)) (p54nrb) (55 kDa nuclear protein) (NMT55) (DNA-binding p52/p100 complex, 52 kDa subunit) | 5 | UniProt NCBI |
| FAM133B | Protein FAM133B | 2 | UniProt NCBI |
| ESCO2 | N-acetyltransferase ESCO2 (EC 2.3.1.-) (Establishment factor-like protein 2) (EFO2) (EFO2p) (hEFO2) (Establishment of cohesion 1 homolog 2) (ECO1 homolog 2) | 5 | UniProt NCBI |
| IFI27L1 | Interferon alpha-inducible protein 27-like protein 1 (Interferon-stimulated gene 12c protein) (ISG12(c)) (ISG12C) | 3 | UniProt NCBI |
| ZNF677 | Zinc finger protein 677 | 3 | UniProt NCBI |
| SFPQ | Splicing factor, proline- and glutamine-rich (100 kDa DNA-pairing protein) (hPOMp100) (DNA-binding p52/p100 complex, 100 kDa subunit) (Polypyrimidine tract-binding protein-associated-splicing factor) (PSF) (PTB-associated-splicing factor) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:7285 | 0.000358447219737 | 0.25 | PSPC1 NONO | HEXIM1-DNA-PK-paraspeckle components-ribonucleoprotein complex |
| HP:0006443 | 0.0306138099712 | 0.25 | ORC6 ESCO2 | Patellar aplasia |
| CORUM:330 | 0.0499436884912 | 0.125 | NONO | PSF-p54(nrb) complex |
| CORUM:1760 | 0.0499436884912 | 0.125 | NONO | TOP1-PSF-P54 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| NONO | SFPQ | 1.0 | 0.992 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt Malo bioplex3_HCT116 fraction boldt_WMM treiber_WMM |
| PSPC1 | NONO | 1.0 | 0.62 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt bioplex3_HCT116 fraction boldt_WMM treiber_WMM |
| PSPC1 | SFPQ | 0.999 | 0.674 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt bioplex3_HCT116 fraction boldt_WMM treiber_WMM |
| IFI27L1 | ORC6 | 0.979 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| ORC6 | NONO | 0.972 | 0.22 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| ZNF677 | ESCO2 | 0.962 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| PSPC1 | ESCO2 | 0.96 | 0.108 | hein_WMM bioplex3_HEK293 bioplex3_WMM youn_WMM gupta_WMM WMM_only |
| ORC6 | SFPQ | 0.959 | 0.12 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| ORC6 | PSPC1 | 0.957 | 0.092 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| PROSER1 | NONO | 0.886 | 0.134 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| NONO | ESCO2 | 0.856 | 0.102 | hein_WMM bioplex3_HEK293 bioplex3_WMM WMM_only |
| FAM133B | SFPQ | 0.85 | 0.068 | bioplex3_WMM WMM_only |
| FAM133B | NONO | 0.85 | 0.094 | bioplex3_WMM WMM_only |
| SFPQ | ESCO2 | 0.843 | 0.074 | hein_WMM bioplex3_HEK293 bioplex3_WMM WMM_only |
| IFI27L1 | FAM133B | 0.339 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| FAM133B | ESCO2 | 0.297 | 0.078 | bioplex3_WMM WMM_only |
| FAM133B | PSPC1 | 0.28 | 0.184 | bioplex3_WMM WMM_only |
| PROSER1 | SFPQ | 0.254 | 0.108 | bioplex_WMM bioplex3_WMM WMM_only |
| PROSER1 | PSPC1 | 0.236 | 0.056 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only |
| IFI27L1 | SFPQ | 0.203 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| IFI27L1 | NONO | 0.167 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| ORC6 | ESCO2 | 0.102 | 0.164 | bioplex3_WMM WMM_only |
| IFI27L1 | PSPC1 | 0.096 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| ORC6 | FAM133B | 0.079 | 0.084 | bioplex3_WMM WMM_only |
| NONO | ZNF677 | 0.054 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| SFPQ | ZNF677 | 0.048 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| PSPC1 | ZNF677 | 0.015 | bioplex3_HEK293 WMM_only |
Related Complexes