hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_13458.1
Complex Portal: CPX-23676
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| TGFA | Protransforming growth factor alpha [Cleaved into: Transforming growth factor alpha (TGF-alpha) (EGF-like TGF) (ETGF) (TGF type 1)] | 5 | UniProt NCBI |
| DHDDS | Dehydrodolichyl diphosphate synthase complex subunit DHDDS (EC 2.5.1.87) (Cis-isoprenyltransferase) (CIT) (Cis-IPTase) (Cis-prenyltransferase subunit hCIT) (Epididymis tissue protein Li 189m) | 5 | UniProt NCBI |
| SPPL2A | Signal peptide peptidase-like 2A (SPP-like 2A) (SPPL2a) (EC 3.4.23.-) (Intramembrane protease 3) (IMP-3) (Presenilin-like protein 2) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:6238 | 0.0499402709677 | 0.333333333333 | DHDDS | DHDDS-NUS1 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| TGFA | SPPL2A | 0.993 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| TGFA | DHDDS | 0.931 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| SPPL2A | DHDDS | 0.113 | 0.152 | bioplex3_WMM WMM_only |
Related Complexes