hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_13487.1
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| OAT | Ornithine aminotransferase, mitochondrial (EC 2.6.1.13) (Ornithine delta-aminotransferase) (Ornithine--oxo-acid aminotransferase) [Cleaved into: Ornithine aminotransferase, hepatic form; Ornithine aminotransferase, renal form] | 5 | UniProt NCBI |
| GSTT2 | Glutathione S-transferase theta-2 (EC 2.5.1.18) (GST class-theta-2) | 4 | UniProt NCBI |
| GPT2 | Alanine aminotransferase 2 (ALT2) (EC 2.6.1.2) (Glutamate pyruvate transaminase 2) (GPT 2) (Glutamic--alanine transaminase 2) (Glutamic--pyruvic transaminase 2) | 5 | UniProt NCBI |
| LBH | Protein LBH (hLBH) (Limb bud and heart development protein homolog) | 5 | UniProt NCBI |
| THEM5 | Acyl-coenzyme A thioesterase THEM5 (Acyl-CoA thioesterase THEM5) (EC 3.1.2.2) (Acyl-coenzyme A thioesterase 15) (Thioesterase superfamily member 5) | 5 | UniProt NCBI |
| THEM4 | Acyl-coenzyme A thioesterase THEM4 (Acyl-CoA thioesterase THEM4) (EC 3.1.2.2) (Carboxyl-terminal modulator protein) (Thioesterase superfamily member 4) | 5 | UniProt NCBI |
| GPT | Alanine aminotransferase 1 (ALT1) (EC 2.6.1.2) (Glutamate pyruvate transaminase 1) (GPT 1) (Glutamic--alanine transaminase 1) (Glutamic--pyruvic transaminase 1) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:00220 | 0.00174822511833 | 0.285714285714 | GPT2 GPT | Arginine biosynthesis |
| GO:0008483 | 0.00273674384085 | 0.428571428571 | OAT GPT GPT2 | transaminase activity |
| KEGG:00062 | 0.00281847850923 | 0.285714285714 | THEM5 THEM4 | Fatty acid elongation |
| GO:0016769 | 0.0032492156641 | 0.428571428571 | OAT GPT GPT2 | transferase activity, transferring nitrogenous groups |
| WP:WP4595 | 0.00337040555802 | 0.285714285714 | OAT GPT | Urea cycle and associated pathways |
| KEGG:01210 | 0.0044360875468 | 0.285714285714 | GPT2 GPT | 2-Oxocarboxylic acid metabolism |
| KEGG:00250 | 0.00474094223862 | 0.285714285714 | GPT2 GPT | Alanine, aspartate and glutamate metabolism |
| GO:0004021 | 0.00983221512175 | 0.285714285714 | GPT2 GPT | L-alanine:2-oxoglutarate aminotransferase activity |
| GO:0047635 | 0.00983221512175 | 0.285714285714 | GPT2 GPT | alanine-oxo-acid transaminase activity |
| REAC:R-HSA-77289 | 0.0212237900738 | 0.285714285714 | THEM5 THEM4 | Mitochondrial Fatty Acid Beta-Oxidation |
| KEGG:01230 | 0.0223578432711 | 0.285714285714 | GPT2 GPT | Biosynthesis of amino acids |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| GPT2 | THEM5 | 1.0 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| GPT2 | GPT | 1.0 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| THEM5 | THEM4 | 0.999 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| OAT | THEM5 | 0.991 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| GPT2 | THEM4 | 0.99 | 0.054 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| THEM4 | GSTT2 | 0.986 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| THEM4 | LBH | 0.985 | 0.064 | bioplex3_HEK293 bioplex3_WMM WMM_only |
| OAT | THEM4 | 0.719 | 0.086 | bioplex3_HEK293 bioplex () bioplex3_WMM youn_WMM |
| GPT2 | GSTT2 | 0.502 | bioplex_WMM bioplex3_WMM WMM_only | |
| GPT2 | OAT | 0.136 | 0.22 | bioplex3_WMM bioplex3_HCT116 treiber_WMM WMM_only |
| GPT | OAT | 0.011 | 0.167333333333 | bioplex3_WMM WMM_only |
| OAT | GSTT2 | 0.006 | bioplex3_HEK293 bioplex () | |
| OAT | LBH | 0.006 | 0.086 | bioplex3_HEK293 WMM_only |
Related Complexes