hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_13489.1
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| TOP3B | DNA topoisomerase 3-beta-1 (EC 5.6.2.1) (DNA topoisomerase III beta-1) | 5 | UniProt NCBI |
| KIF1C | Kinesin-like protein KIF1C | 5 | UniProt NCBI |
| TDRD3 | Tudor domain-containing protein 3 | 5 | UniProt NCBI |
| KIF1A | Kinesin-like protein KIF1A (Axonal transporter of synaptic vesicles) (Microtubule-based motor KIF1A) (Unc-104- and KIF1A-related protein) (hUnc-104) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:7407 | 5.12628525639e-06 | 0.5 | TOP3B TDRD3 | TOP3B-c complex |
| GO:0140225 | 0.0028092043205 | 0.5 | TOP3B TDRD3 | DNA topoisomerase III-beta-TDRD3 complex |
| REAC:R-HSA-983189 | 0.0146019089592 | 0.5 | KIF1C KIF1A | Kinesins |
| GO:1990049 | 0.0168521501606 | 0.5 | KIF1C KIF1A | retrograde neuronal dense core vesicle transport |
| GO:1990048 | 0.0280843539964 | 0.5 | KIF1C KIF1A | anterograde neuronal dense core vesicle transport |
| KEGG:04814 | 0.0322340970049 | 0.5 | KIF1C KIF1A | Motor proteins |
| HP:0011448 | 0.036003514982 | 0.5 | KIF1C KIF1A | Ankle clonus |
| REAC:R-HSA-6811434 | 0.0434971593242 | 0.5 | KIF1C KIF1A | COPI-dependent Golgi-to-ER retrograde traffic |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| TOP3B | TDRD3 | 0.999 | 0.425307692308 | hein_WMM youn () bioplex3_HEK293 Guru bioplex3_WMM youn_WMM gupta_WMM fraction |
| KIF1C | KIF1A | 0.972 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM WMM_only | |
| TOP3B | KIF1C | 0.953 | 0.158 | hein_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only |
| TDRD3 | KIF1C | 0.926 | 0.088 | hein_WMM youn () bioplex3_WMM youn_WMM gupta_WMM WMM_only |
| TOP3B | KIF1A | 0.004 | youn_WMM gupta_WMM WMM_only | |
| TDRD3 | KIF1A | 0.002 | youn () youn_WMM gupta_WMM WMM_only |
Related Complexes