hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_13496.1
Complex Portal: CPX-25134
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| CD33 | Myeloid cell surface antigen CD33 (Sialic acid-binding Ig-like lectin 3) (Siglec-3) (gp67) (CD antigen CD33) | 5 | UniProt NCBI |
| C22orf39 | Synaptic plasticity regulator PANTS (Plasticity-associated neural transcript short) | 5 | UniProt NCBI |
| MYO3A | Myosin-IIIa (EC 2.7.11.1) | 5 | UniProt NCBI |
| TNNC1 | Troponin C, slow skeletal and cardiac muscles (TN-C) | 5 | UniProt NCBI |
| TNNT1 | Troponin T, slow skeletal muscle (TnTs) (Slow skeletal muscle troponin T) (sTnT) | 5 | UniProt NCBI |
| TNNI3 | Troponin I, cardiac muscle (Cardiac troponin I) | 5 | UniProt NCBI |
| TNNI2 | Troponin I, fast skeletal muscle (Troponin I, fast-twitch isoform) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:04814 | 0.000236813619879 | 0.75 | TNNI2 MYO3A TNNC1 | Motor proteins |
| WP:WP383 | 0.00151495259867 | 0.5 | TNNC1 TNNI2 | Striated muscle contraction pathway |
| REAC:R-HSA-390522 | 0.00539805716719 | 0.5 | TNNC1 TNNI2 | Striated Muscle Contraction |
| GO:0031014 | 0.0168521501606 | 0.5 | TNNC1 TNNI2 | troponin T binding |
| GO:0005861 | 0.042122686785 | 0.5 | TNNC1 TNNI2 | troponin complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| TNNI2 | TNNC1 | 0.997 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| TNNI3 | TNNT1 | 0.997 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| TNNI3 | TNNC1 | 0.996 |
structurally_consistent (dimer)
|
bioplex3_WMM bioplex3_HCT116 WMM_only | |
| TNNI2 | TNNT1 | 0.994 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| TNNC1 | C22orf39 | 0.979 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| TNNC1 | MYO3A | 0.937 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| TNNC1 | CD33 | 0.868 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| TNNC1 | TNNT1 | 0.616 | bioplex3_WMM WMM_only | ||
| C22orf39 | CD33 | 0.146 | bioplex3_WMM WMM_only | ||
| CD33 | MYO3A | 0.146 | bioplex3_WMM WMM_only | ||
| C22orf39 | MYO3A | 0.095 | bioplex3_WMM WMM_only |
Related Complexes