hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_13505.1
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| SNX30 | Sorting nexin-30 | 5 | UniProt NCBI |
| SNX7 | Sorting nexin-7 | 5 | UniProt NCBI |
| SNX4 | Sorting nexin-4 | 5 | UniProt NCBI |
| CAVIN2 | Caveolae-associated protein 2 (Cavin-2) (PS-p68) (Phosphatidylserine-binding protein) (Serum deprivation-response protein) | 5 | UniProt NCBI |
| MECR | Enoyl-[acyl-carrier-protein] reductase, mitochondrial (EC 1.3.1.104) (2-enoyl thioester reductase) (Nuclear receptor-binding factor 1) (HsNrbf-1) (NRBF-1) | 5 | UniProt NCBI |
| DMRT1 | Doublesex- and mab-3-related transcription factor 1 (DM domain expressed in testis protein 1) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:2000786 | 0.00130441648129 | 0.5 | SNX7 SNX30 SNX4 | positive regulation of autophagosome assembly |
| GO:0044090 | 0.00295184433846 | 0.5 | SNX7 SNX30 SNX4 | positive regulation of vacuole organization |
| GO:2000785 | 0.017471616814 | 0.5 | SNX7 SNX30 SNX4 | regulation of autophagosome assembly |
| GO:0044088 | 0.0330200031842 | 0.5 | SNX7 SNX30 SNX4 | regulation of vacuole organization |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| SNX4 | SNX30 | 1.0 | 0.172 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| SNX4 | SNX7 | 0.999 | 0.146 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| DMRT1 | CAVIN2 | 0.997 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| MECR | SNX4 | 0.985 | 0.02 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only |
| MECR | DMRT1 | 0.962 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| MECR | CAVIN2 | 0.893 | 0.013 | bioplex3_WMM WMM_only |
| MECR | SNX30 | 0.893 | 0.014 | bioplex3_HEK293 bioplex3_WMM WMM_only |
Related Complexes