hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_13531.1
Complex Portal: CPX-20653
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| CD1E | T-cell surface glycoprotein CD1e, membrane-associated (hCD1e) (R2G1) (CD antigen CD1e) [Cleaved into: T-cell surface glycoprotein CD1e, soluble (sCD1e)] | 5 | UniProt NCBI |
| HFE | Hereditary hemochromatosis protein (HLA-H) | 5 | UniProt NCBI |
| KCNJ8 | ATP-sensitive inward rectifier potassium channel 8 (Inward rectifier K(+) channel Kir6.1) (Potassium channel, inwardly rectifying subfamily J member 8) (uKATP-1) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HP:0001640 | 0.0227948817734 | 1.0 | HFE KCNJ8 | Cardiomegaly |
| WP:WP3924 | 0.0310970405539 | 0.5 | HFE | Hfe effect on hepcidin production |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| CD1E | KCNJ8 | 0.968 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| HFE | KCNJ8 | 0.814 | bioplex3_HEK293 bioplex3_WMM WMM_only |
Related Complexes