hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_13535.1

Confidence: Medium

Genename	Protein Name	Uniprot Annotation Score	Links
SEC24C	Protein transport protein Sec24C (SEC24-related protein C)	5	UniProt NCBI
TRPC5	Short transient receptor potential channel 5 (TrpC5) (Transient receptor protein 5) (TRP-5) (hTRP-5) (hTRP5)	5	UniProt NCBI
SEC23A	Protein transport protein Sec23A (hSec23A) (SEC23-related protein A)	5	UniProt NCBI
SEC23IP	SEC23-interacting protein (p125)	5	UniProt NCBI
SMG7	Nonsense-mediated mRNA decay factor SMG7 (SMG-7 homolog) (hSMG-7)	5	UniProt NCBI
PRRC1	Protein PRRC1 (Proline-rich and coiled-coil-containing protein 1)	5	UniProt NCBI
SEC24B	Protein transport protein Sec24B (SEC24-related protein B)	5	UniProt NCBI
SEC23B	Protein transport protein Sec23B (hSec23B) (SEC23-related protein B)	5	UniProt NCBI
SEC24A	Protein transport protein Sec24A (SEC24-related protein A)	5	UniProt NCBI
KIAA1217	Sickle tail protein homolog	5	UniProt NCBI
SRA1	Steroid receptor RNA activator 1 (Steroid receptor RNA activator protein) (SRAP)	5	UniProt NCBI
HSCB	Iron-sulfur cluster co-chaperone protein HscB (DnaJ homolog subfamily C member 20) [Cleaved into: Iron-sulfur cluster co-chaperone protein HscB, cytoplasmic (C-HSC20); Iron-sulfur cluster co-chaperone protein HscB, mitochondrial]	5	UniProt NCBI
SEC24D	Protein transport protein Sec24D (SEC24-related protein D)	5	UniProt NCBI
RUBCNL	Protein associated with UVRAG as autophagy enhancer (Pacer) (Protein Rubicon-like)	5	UniProt NCBI

Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
GO:0030127	8.85106130962e-11	0.428571428571	SEC23B SEC24B SEC24C SEC24D SEC24A SEC23A	COPII vesicle coat
GO:0090110	8.85106130962e-11	0.428571428571	SEC23B SEC24B SEC24C SEC24D SEC24A SEC23A	COPII-coated vesicle cargo loading
GO:0070971	2.53275250926e-09	0.428571428571	SEC23B SEC24B SEC24C SEC24D SEC24A SEC23A	endoplasmic reticulum exit site
WP:WP1982	2.75182959818e-09	0.428571428571	SEC23B SEC24B SEC24C SEC24D SEC24A SEC23A	Sterol regulatory element binding proteins SREBP signaling
REAC:R-HSA-204005	3.37561337932e-09	0.428571428571	SEC23A SEC24B SEC24C SEC24D SEC24A SEC23IP	COPII-mediated vesicle transport
GO:0035459	8.0807901501e-09	0.428571428571	SEC23B SEC24B SEC24C SEC24D SEC24A SEC23A	vesicle cargo loading
REAC:R-HSA-5694530	8.08397706745e-09	0.357142857143	SEC24A SEC24B SEC24D SEC24C SEC23A	Cargo concentration in the ER
REAC:R-HSA-983170	8.08397706745e-09	0.357142857143	SEC24A SEC24B SEC24D SEC24C SEC23A	Antigen Presentation: Folding, assembly and peptide loading of class I MHC
GO:0030134	9.63722874168e-09	0.5	SEC23B SEC24B SEC24C SEC24D SEC23IP SEC23A SEC24A	COPII-coated ER to Golgi transport vesicle
GO:0090114	3.5673328039e-08	0.428571428571	SEC23B SEC24B SEC24C SEC24D SEC24A SEC23A	COPII-coated vesicle budding
GO:0012507	1.33609192146e-07	0.428571428571	SEC23B SEC24B SEC24C SEC24D SEC24A SEC23A	ER to Golgi transport vesicle membrane
KEGG:04141	2.0902994456e-07	0.428571428571	SEC23B SEC24B SEC24C SEC24D SEC24A SEC23A	Protein processing in endoplasmic reticulum
REAC:R-HSA-1655829	2.09669573382e-07	0.357142857143	SEC24A SEC24B SEC24D SEC24C SEC23A	Regulation of cholesterol biosynthesis by SREBP (SREBF)
CORUM:7141	3.64803730192e-07	0.214285714286	SEC24B SEC23A SEC23IP	Coat protein complex II (SAR1B, PREB, SEC23A , SEC24B, SEC23IP)
GO:0030120	3.93427767164e-07	0.428571428571	SEC23B SEC24B SEC24C SEC24D SEC24A SEC23A	vesicle coat
REAC:R-HSA-199977	6.24589048804e-07	0.428571428571	SEC23A SEC24B SEC24C SEC24D SEC24A SEC23IP	ER to Golgi Anterograde Transport
GO:0006900	1.68197991065e-06	0.428571428571	SEC23B SEC24B SEC24C SEC24D SEC24A SEC23A	vesicle budding from membrane
REAC:R-HSA-948021	1.89957708929e-06	0.428571428571	SEC23A SEC24B SEC24C SEC24D SEC24A SEC23IP	Transport to the Golgi and subsequent modification
GO:0048475	5.3980551127e-06	0.428571428571	SEC23B SEC24B SEC24C SEC24D SEC24A SEC23A	coated membrane
GO:0030117	5.3980551127e-06	0.428571428571	SEC23B SEC24B SEC24C SEC24D SEC24A SEC23A	membrane coat
REAC:R-HSA-9705671	1.28583221928e-05	0.357142857143	SEC24A SEC24B SEC24D SEC24C SEC23A	SARS-CoV-2 activates/modulates innate and adaptive immune responses
REAC:R-HSA-2132295	1.60178783308e-05	0.357142857143	SEC24A SEC24B SEC24D SEC24C SEC23A	MHC class II antigen presentation
REAC:R-HSA-8957322	1.97658190343e-05	0.357142857143	SEC24A SEC24B SEC24D SEC24C SEC23A	Metabolism of steroids
GO:0030135	2.74669976011e-05	0.5	SEC23B SEC24B SEC24C SEC24D SEC23IP SEC23A SEC24A	coated vesicle
GO:0030658	2.96830182261e-05	0.428571428571	SEC23B SEC24B SEC24C SEC24D SEC24A SEC23A	transport vesicle membrane
GO:0006888	3.47124412241e-05	0.428571428571	SEC23B SEC24B SEC24C SEC24D SEC24A SEC23A	endoplasmic reticulum to Golgi vesicle-mediated transport
REAC:R-HSA-446203	3.70198674348e-05	0.428571428571	SEC23A SEC24B SEC24C SEC24D SEC24A SEC23IP	Asparagine N-linked glycosylation
CORUM:7139	4.44741811353e-05	0.142857142857	SEC23A SEC24B	SEC23-SEC24 adaptor complex
GO:0030662	0.000131326613578	0.428571428571	SEC23B SEC24B SEC24C SEC24D SEC24A SEC23A	coated vesicle membrane
GO:0016050	0.000137882024839	0.5	SEC23B SEC24B SEC24C SEC24D SEC24A RUBCNL SEC23A	vesicle organization
REAC:R-HSA-9705683	0.000170941025338	0.357142857143	SEC24A SEC24B SEC24D SEC24C SEC23A	SARS-CoV-2-host interactions
CORUM:7140	0.000266552996475	0.142857142857	SEC23A SEC24B	SEC23-SEC24-SCAP-SREBP1c complex
GO:0061024	0.000580721403071	0.571428571429	TRPC5 SEC23B SEC24B SEC24C SEC24D SEC24A RUBCNL SEC23A	membrane organization
KEGG:05130	0.00079847021956	0.285714285714	SEC24D SEC24A SEC24C SEC24B	Pathogenic Escherichia coli infection
REAC:R-HSA-9694516	0.00107403403215	0.357142857143	SEC24A SEC24B SEC24D SEC24C SEC23A	SARS-CoV-2 Infection
REAC:R-HSA-199991	0.00228040119927	0.428571428571	SEC23A SEC24B SEC24C SEC24D SEC24A SEC23IP	Membrane Trafficking
REAC:R-HSA-5653656	0.0031153160115	0.428571428571	SEC23A SEC24B SEC24C SEC24D SEC24A SEC23IP	Vesicle-mediated transport
GO:0030133	0.00331186323588	0.428571428571	SEC23B SEC24B SEC24C SEC24D SEC24A SEC23A	transport vesicle
REAC:R-HSA-983169	0.00340782680878	0.357142857143	SEC24A SEC24B SEC24D SEC24C SEC23A	Class I MHC mediated antigen processing & presentation
GO:0048193	0.00498749433324	0.428571428571	SEC23B SEC24B SEC24C SEC24D SEC24A SEC23A	Golgi vesicle transport
REAC:R-HSA-9679506	0.00509625430485	0.357142857143	SEC24A SEC24B SEC24D SEC24C SEC23A	SARS-CoV Infections
TF:M11235_1	0.00574694403184	0.214285714286	SEC24D SEC23A SEC24A	Factor: OASIS; motif: YGCCACGTCANC; match class: 1
HP:0002868	0.0325097356017	0.142857142857	SEC24D SEC23A	Narrow iliac wing

Edges

Protein 1	Protein 2	Score	ProteomeHD
SEC23B	SEC24A	1.0	0.25
SEC23B	SEC24C	1.0	0.268
SEC23A	SEC24C	1.0	0.53
SEC23B	SEC23A	1.0	0.106
SEC23A	SEC24A	1.0	0.308
SEC23B	SEC24B	0.999	0.102
SEC23A	SEC24B	0.999	0.286666666667
SEC24B	SEC24A	0.996	0.156
SEC23A	SEC23IP	0.995	0.254
SEC23B	SEC24D	0.993	0.208
SEC24C	SEC24B	0.992	0.27
SEC24C	SEC24A	0.991	0.386
SEC23B	SEC23IP	0.99	0.092
SEC23A	SEC24D	0.981	0.302631578947
RUBCNL	SEC24A	0.978
HSCB	PRRC1	0.971	0.27156097561
SEC24B	TRPC5	0.969
SEC24D	SEC24A	0.963	0.266
SEC24C	PRRC1	0.955	0.174
PRRC1	SEC24A	0.954	0.132
SEC24D	PRRC1	0.938	0.216
SEC24B	PRRC1	0.935	0.066
SEC23B	SRA1	0.931	0.072
SEC23A	PRRC1	0.926	0.19
SEC23A	SRA1	0.923	0.052
TRPC5	SEC24A	0.922
SEC23B	RUBCNL	0.916
SEC24C	SRA1	0.915	0.1
SEC24D	SRA1	0.913	0.034
SEC23A	KIAA1217	0.91	0.072
RUBCNL	SEC24B	0.908
SMG7	SEC24A	0.857	0.214
KIAA1217	SEC24A	0.841	0.092
KIAA1217	SEC24C	0.823	0.058
SEC23A	SMG7	0.82	0.072
SEC23B	SMG7	0.815	0.116
RUBCNL	SEC24C	0.728
SEC23B	PRRC1	0.682	0.108
SEC24D	SEC24C	0.602	0.136
KIAA1217	SEC24B	0.543	0.098
SEC23IP	SMG7	0.448	0.258
SEC23B	KIAA1217	0.443	0.104
SEC24A	SRA1	0.391	0.122
SEC23B	TRPC5	0.38
SEC24D	SEC24B	0.342	0.116
SEC23A	TRPC5	0.332
KIAA1217	SMG7	0.328	0.096
SEC24B	SRA1	0.327	0.04
SEC23A	RUBCNL	0.306
SEC24B	SMG7	0.275	0.202
SEC23IP	SEC24B	0.242	0.184
SEC24C	SMG7	0.177	0.154
SEC23IP	SEC24A	0.124	0.216
SEC23IP	PRRC1	0.11	0.104
SEC24D	SEC23IP	0.106	0.146
SEC23IP	SEC24C	0.07	0.516
KIAA1217	SRA1	0.054	0.07
SEC24D	SMG7	0.018	0.05
SEC24D	HSCB	0.016	0.3353735363
KIAA1217	HSCB	0.013	0.082
HSCB	SEC24A	0.012	0.29
PRRC1	SMG7	0.011	0.186
SEC24D	KIAA1217	0.011	0.094
SEC23A	HSCB	0.009	0.132
SEC24C	HSCB	0.008	0.318
SEC23B	HSCB	0.006	0.308
KIAA1217	PRRC1	0.006	0.06
SEC24B	HSCB	0.005	0.264357142857
SEC23IP	KIAA1217	0.004	0.076

Related Complexes

Genename	Complexes
SEC24C	huMAP3_00707.1 huMAP3_06453.1 huMAP3_06773.1 huMAP3_07775.1 huMAP3_09282.1 huMAP3_11128.1 huMAP3_11237.1 huMAP3_12394.1 huMAP3_13535.1
TRPC5	huMAP3_03680.1 huMAP3_05704.1 huMAP3_09201.1 huMAP3_10615.1 huMAP3_11237.1 huMAP3_12394.1 huMAP3_13535.1 huMAP3_13878.1
SEC23A	huMAP3_00065.1 huMAP3_00707.1 huMAP3_06453.1 huMAP3_07775.1 huMAP3_09282.1 huMAP3_11128.1 huMAP3_11237.1 huMAP3_12394.1 huMAP3_13535.1
SEC23IP	huMAP3_00065.1 huMAP3_06701.1 huMAP3_07775.1 huMAP3_09282.1 huMAP3_11128.1 huMAP3_13535.1
SMG7	huMAP3_05373.1 huMAP3_10798.1 huMAP3_13535.1
PRRC1	huMAP3_01462.1 huMAP3_08752.1 huMAP3_11237.1 huMAP3_11419.1 huMAP3_13535.1
SEC24B	huMAP3_01115.1 huMAP3_04806.1 huMAP3_06453.1 huMAP3_09201.1 huMAP3_10615.1 huMAP3_11128.1 huMAP3_11237.1 huMAP3_12394.1 huMAP3_12918.1 huMAP3_13535.1
SEC23B	huMAP3_00065.1 huMAP3_00707.1 huMAP3_06453.1 huMAP3_07775.1 huMAP3_09282.1 huMAP3_11128.1 huMAP3_11237.1 huMAP3_12394.1 huMAP3_13535.1
SEC24A	huMAP3_06453.1 huMAP3_09282.1 huMAP3_11128.1 huMAP3_11237.1 huMAP3_12394.1 huMAP3_13535.1
KIAA1217	huMAP3_00221.1 huMAP3_09553.1 huMAP3_11011.1 huMAP3_11237.1 huMAP3_12394.1 huMAP3_13535.1 huMAP3_14660.1
SRA1	huMAP3_11237.1 huMAP3_12394.1 huMAP3_12641.1 huMAP3_13535.1
HSCB	huMAP3_01462.1 huMAP3_08752.1 huMAP3_11237.1 huMAP3_11419.1 huMAP3_12346.1 huMAP3_13535.1
SEC24D	huMAP3_00065.1 huMAP3_00707.1 huMAP3_06453.1 huMAP3_07775.1 huMAP3_09282.1 huMAP3_11128.1 huMAP3_11237.1 huMAP3_12394.1 huMAP3_12641.1 huMAP3_13535.1
RUBCNL	huMAP3_00300.1 huMAP3_01249.1 huMAP3_11237.1 huMAP3_11445.1 huMAP3_13535.1 huMAP3_14783.1

hu.MAP 3.0: Complex View

Search for a protein

Complex: huMAP3_13535.1