hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_13561.1
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| ATP1B3 | Sodium/potassium-transporting ATPase subunit beta-3 (Sodium/potassium-dependent ATPase subunit beta-3) (ATPB-3) (CD antigen CD298) | 5 | UniProt NCBI |
| FXYD1 | Phospholemman (FXYD domain-containing ion transport regulator 1) (Sodium/potassium-transporting ATPase subunit FXYD1) | 5 | UniProt NCBI |
| NDRG3 | Protein NDRG3 (N-myc downstream-regulated gene 3 protein) | 3 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-936837 | 0.00478550282195 | 0.666666666667 | FXYD1 ATP1B3 | Ion transport by P-type ATPases |
| REAC:R-HSA-5578775 | 0.005581186855 | 0.666666666667 | FXYD1 ATP1B3 | Ion homeostasis |
| GO:1903276 | 0.00842684400117 | 0.666666666667 | FXYD1 ATP1B3 | regulation of sodium ion export across plasma membrane |
| GO:1903278 | 0.00842684400117 | 0.666666666667 | FXYD1 ATP1B3 | positive regulation of sodium ion export across plasma membrane |
| KEGG:04024 | 0.00940070336911 | 0.666666666667 | FXYD1 ATP1B3 | cAMP signaling pathway |
| REAC:R-HSA-5576891 | 0.0242497192193 | 0.666666666667 | FXYD1 ATP1B3 | Cardiac conduction |
| REAC:R-HSA-9679191 | 0.0242497192193 | 0.666666666667 | FXYD1 ATP1B3 | Potential therapeutics for SARS |
| GO:0005890 | 0.0393180950424 | 0.666666666667 | FXYD1 ATP1B3 | sodium:potassium-exchanging ATPase complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| NDRG3 | ATP1B3 | 0.964 | 0.016 | bioplex3_WMM bioplex3_HCT116 gupta_WMM WMM_only |
| NDRG3 | FXYD1 | 0.939 | bioplex3_HEK293 bioplex () | |
| ATP1B3 | FXYD1 | 0.005 | bioplex3_HEK293 bioplex () |
Related Complexes