hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_13580.1
Complex Portal: CPX-16138
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| UQCC1 | Ubiquinol-cytochrome c reductase complex assembly factor 1 (Basic FGF-repressed Zic-binding protein) (bFGF-repressed Zic-binding protein) (bFZb) (Ubiquinol-cytochrome c reductase complex chaperone CBP3 homolog) | 5 | UniProt NCBI |
| PPT1 | Palmitoyl-protein thioesterase 1 (PPT-1) (EC 3.1.2.22) (Palmitoyl-protein hydrolase 1) | 5 | UniProt NCBI |
| COX20 | Cytochrome c oxidase assembly protein COX20, mitochondrial | 5 | UniProt NCBI |
| UQCC4 | Ubiquinol-cytochrome c reductase complex assembly factor 4 (Protein CCSMST1) | 3 | UniProt NCBI |
| UQCC2 | Ubiquinol-cytochrome c reductase complex assembly factor 2 (Breast cancer-associated protein SGA-81M) (Mitochondrial nucleoid factor 1) (Mitochondrial protein M19) | 5 | UniProt NCBI |
| GCDH | Glutaryl-CoA dehydrogenase, mitochondrial (GCD) (EC 1.3.8.6) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0017004 | 2.05958456954e-05 | 0.666666666667 | UQCC1 UQCC2 UQCC4 COX20 | cytochrome complex assembly |
| GO:0017062 | 0.000316805542726 | 0.5 | UQCC1 UQCC2 UQCC4 | respiratory chain complex III assembly |
| GO:0034551 | 0.000316805542726 | 0.5 | UQCC1 UQCC2 UQCC4 | mitochondrial respiratory chain complex III assembly |
| WP:WP4921 | 0.00105547828549 | 0.333333333333 | UQCC1 UQCC2 | Mitochondrial complex III assembly |
| GO:0033108 | 0.00109222246905 | 0.666666666667 | UQCC1 UQCC2 UQCC4 COX20 | mitochondrial respiratory chain complex assembly |
| HP:0002072 | 0.0435813356909 | 0.5 | PPT1 GCDH COX20 | Chorea |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| UQCC1 | UQCC2 | 0.999 | 0.852 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt youn_WMM bioplex3_HCT116 boldt_WMM | |
| UQCC4 | COX20 | 0.948 | 0.236 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| PPT1 | COX20 | 0.942 | 0.014 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| COX20 | GCDH | 0.905 | 0.024 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| PPT1 | GCDH | 0.893 | 0.016 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM WMM_only | |
| UQCC1 | UQCC4 | 0.892 | 0.254 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM WMM_only | |
| UQCC2 | COX20 | 0.883 | 0.098 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| UQCC1 | COX20 | 0.81 | 0.214 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| UQCC2 | UQCC4 | 0.653 | 0.212 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM WMM_only | |
| PPT1 | UQCC4 | 0.086 | 0.044 | bioplex_WMM bioplex3_WMM WMM_only | |
| UQCC4 | GCDH | 0.05 | 0.106 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM WMM_only | |
| UQCC2 | GCDH | 0.026 | 0.022 | bioplex_WMM bioplex3_WMM WMM_only | |
| PPT1 | UQCC2 | 0.02 | 0.016 | bioplex_WMM bioplex3_WMM WMM_only | |
| UQCC1 | GCDH | 0.019 | 0.056 | bioplex_WMM bioplex3_WMM WMM_only | |
| PPT1 | UQCC1 | 0.009 | 0.028 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes