hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_13582.1
Complex Portal: CPX-13978
Confidence: Medium  
ProteinsGenename | Protein Name | Uniprot Annotation Score | Links |
---|---|---|---|
FLT4 | Vascular endothelial growth factor receptor 3 (VEGFR-3) (EC 2.7.10.1) (Fms-like tyrosine kinase 4) (FLT-4) (Tyrosine-protein kinase receptor FLT4) | 5 | UniProt   NCBI |
ERBB2 | Receptor tyrosine-protein kinase erbB-2 (EC 2.7.10.1) (Metastatic lymph node gene 19 protein) (MLN 19) (Proto-oncogene Neu) (Proto-oncogene c-ErbB-2) (Tyrosine kinase-type cell surface receptor HER2) (p185erbB2) (CD antigen CD340) | 5 | UniProt   NCBI |
Enrichments
Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
---|---|---|---|---|
  KEGG:05224 | 0.00130072012548 | 1.0 | FLT4 ERBB2 | Breast cancer |
  KEGG:04020 | 0.00239074992693 | 1.0 | FLT4 ERBB2 | Calcium signaling pathway |
  KEGG:04510 | 0.00241871191437 | 1.0 | FLT4 ERBB2 | Focal adhesion |
  WP:WP4262 | 0.00373624174627 | 1.0 | FLT4 ERBB2 | Breast cancer pathway |
  KEGG:04010 | 0.0047800367266 | 1.0 | FLT4 ERBB2 | MAPK signaling pathway |
  KEGG:04151 | 0.00662552789826 | 1.0 | FLT4 ERBB2 | PI3K-Akt signaling pathway |
  KEGG:05200 | 0.0161326036311 | 1.0 | FLT4 ERBB2 | Pathways in cancer |
  CORUM:2528 | 0.0499419797295 | 0.5 | ERBB2 | ERBB2-MEMO-SHC complex |
  CORUM:5740 | 0.0499419797295 | 0.5 | FLT4 | NRP2-VEGFR3 complex |
  CORUM:6586 | 0.0499419797295 | 0.5 | FLT4 | VEcad-VEGFR complex |
  CORUM:7351 | 0.0499419797295 | 0.5 | ERBB2 | GDF15-ERBB2 complex |
  CORUM:6506 | 0.0499419797295 | 0.5 | ERBB2 | ERBB2-SPG1 complex |
  HP:0032344 | 0.0499436884913 | 0.5 | FLT4 | Upslanting toenail |
  HP:0003759 | 0.0499436884913 | 0.5 | FLT4 | Hypoplasia of lymphatic vessels |
  HP:0005134 | 0.0499436884913 | 0.5 | FLT4 | Absence of the pulmonary valve |
  HP:0007448 | 0.0499436884913 | 0.5 | FLT4 | Hyperkeratosis over edematous areas |
  HP:0011284 | 0.0499436884913 | 0.5 | ERBB2 | Short-segment aganglionic megacolon |
Edges
Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
---|---|---|---|---|---|
 ERBB2 |  FLT4 | 0.839 | 0.136           |          | bioplex_WMM     bioplex3_WMM     WMM_only     |
Related Complexes