hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_13584.1
Confidence: Medium  
ProteinsGenename | Protein Name | Uniprot Annotation Score | Links |
---|---|---|---|
PIWIL1 | Piwi-like protein 1 (EC 3.1.26.-) | 5 | UniProt   NCBI |
PIWIL4 | Piwi-like protein 4 | 5 | UniProt   NCBI |
TDRKH | Tudor and KH domain-containing protein (Tudor domain-containing protein 2) | 5 | UniProt   NCBI |
Enrichments
Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
---|---|---|---|---|
  REAC:R-HSA-5601884 | 8.26352391973e-07 | 1.0 | PIWIL4 PIWIL1 TDRKH | PIWI-interacting RNA (piRNA) biogenesis |
  GO:0034587 | 3.49876949518e-05 | 1.0 | PIWIL4 PIWIL1 TDRKH | piRNA processing |
  GO:0043186 | 6.5361627932e-05 | 1.0 | PIWIL4 PIWIL1 TDRKH | P granule |
  GO:0045495 | 6.5361627932e-05 | 1.0 | PIWIL4 PIWIL1 TDRKH | pole plasm |
  GO:0060293 | 6.5361627932e-05 | 1.0 | PIWIL4 PIWIL1 TDRKH | germ plasm |
  REAC:R-HSA-211000 | 0.000124543577107 | 1.0 | PIWIL4 PIWIL1 TDRKH | Gene Silencing by RNA |
  GO:0034584 | 0.00140460216025 | 0.666666666667 | PIWIL4 PIWIL1 | piRNA binding |
  GO:0070918 | 0.00252170927764 | 1.0 | PIWIL4 PIWIL1 TDRKH | regulatory ncRNA processing |
  WP:WP4673 | 0.00777794899874 | 0.666666666667 | PIWIL4 PIWIL1 | Male infertility |
  HPA:0570763 | 0.0119453326684 | 1.0 | PIWIL4 PIWIL1 TDRKH | testis; pachytene spermatocytes[High] |
  GO:0031047 | 0.0128843147861 | 1.0 | PIWIL4 PIWIL1 TDRKH | regulatory ncRNA-mediated gene silencing |
  GO:0071547 | 0.0140440992017 | 0.666666666667 | PIWIL4 TDRKH | piP-body |
  GO:0141005 | 0.0393180950424 | 0.666666666667 | PIWIL4 PIWIL1 | retrotransposon silencing by heterochromatin formation |
Edges
Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
---|---|---|---|---|
 PIWIL4 |  TDRKH | 0.908 |            | bioplex3_HEK293     bioplex3_WMM     WMM_only     |
 PIWIL1 |  TDRKH | 0.822 |            | bioplex3_HEK293     bioplex3_WMM     WMM_only     |
Related Complexes
Genename | Complexes |
---|---|
PIWIL1 | huMAP3_13124.1 huMAP3_13584.1 huMAP3_15119.1 |
PIWIL4 | huMAP3_13124.1 huMAP3_13584.1 huMAP3_15119.1 |
TDRKH | huMAP3_13124.1 huMAP3_13584.1 huMAP3_15119.1 |