hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_13602.1
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| CCDC60 | Coiled-coil domain-containing protein 60 | 2 | UniProt NCBI |
| UPF2 | Regulator of nonsense transcripts 2 (Up-frameshift suppressor 2 homolog) (hUpf2) | 5 | UniProt NCBI |
| UPF3B | Regulator of nonsense transcripts 3B (Nonsense mRNA reducing factor 3B) (Up-frameshift suppressor 3 homolog B) (hUpf3B) (Up-frameshift suppressor 3 homolog on chromosome X) (hUpf3p-X) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:813 | 1.02521027753e-05 | 0.666666666667 | UPF2 UPF3B | Upf complex (UPF1, UPF2, UPF3b) |
| CORUM:777 | 5.12534978153e-05 | 0.666666666667 | UPF2 UPF3B | Exon junction complex |
| CORUM:6742 | 5.12534978153e-05 | 0.666666666667 | UPF2 UPF3B | SMG1-UPF2-Y14-MAGOH-UPF3B-EIF4A3 complex |
| CORUM:814 | 7.17516227795e-05 | 0.666666666667 | UPF2 UPF3B | Postsplicing complex |
| CORUM:822 | 0.0001537324292 | 0.666666666667 | UPF2 UPF3B | mRNA decay complex (UPF1, UPF2, UPF3B, DCP2, XRN1, XRN2, EXOSC2, EXOSC4, EXOSC10, PARN) |
| KEGG:03015 | 0.00311331063035 | 0.666666666667 | UPF2 UPF3B | mRNA surveillance pathway |
| KEGG:03013 | 0.00383761092368 | 0.666666666667 | UPF2 UPF3B | Nucleocytoplasmic transport |
| REAC:R-HSA-975957 | 0.0436932800731 | 0.666666666667 | UPF2 UPF3B | Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) |
| REAC:R-HSA-927802 | 0.0436932800731 | 0.666666666667 | UPF2 UPF3B | Nonsense-Mediated Decay (NMD) |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| UPF2 | UPF3B | 0.982 | 0.06 | hein_WMM bioplex3_WMM youn_WMM hein () Malo fraction |
| UPF3B | CCDC60 | 0.88 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
Related Complexes