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hu.MAP 3.0
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hu.MAP 3.0: Complex View
Human Protein Complex Map
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List of Gene Names or Uniprot ACCs (ex. OFD1 PCM1 Q1MSJ5):
Enrichment (ex. cilium):
Protein (ex. Centrosomal protein):
Complex:
huMAP3_13609.1
Complex Portal:
CPX-23938
Confidence:
Medium
?
Proteins
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Genename
Protein Name
Uniprot Annotation Score
Links
DEGS1
Sphingolipid delta(4)-desaturase DES1 (EC 1.14.19.17) (Cell migration-inducing gene 15 protein) (Degenerative spermatocyte homolog 1) (Dihydroceramide desaturase-1) (Membrane lipid desaturase) (Retinol isomerase) (EC 5.2.1.-)
5
UniProt
NCBI
FADS1
Acyl-CoA (8-3)-desaturase (EC 1.14.19.44) (Delta(5) fatty acid desaturase) (D5D) (Delta(5) desaturase) (Delta-5 desaturase) (Fatty acid desaturase 1)
5
UniProt
NCBI
NPLOC4
Nuclear protein localization protein 4 homolog (Protein NPL4)
5
UniProt
NCBI
TMEM31
Transmembrane protein 31
2
UniProt
NCBI
TMEM62
Transmembrane protein 62
2
UniProt
NCBI
UFD1
Ubiquitin recognition factor in ER-associated degradation protein 1 (Ubiquitin fusion degradation protein 1) (UB fusion protein 1)
5
UniProt
NCBI
VCP
Transitional endoplasmic reticulum ATPase (TER ATPase) (EC 3.6.4.6) (15S Mg(2+)-ATPase p97 subunit) (Valosin-containing protein) (VCP)
5
UniProt
NCBI
Showing 1 to 7 of 7 entries
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Enrichments
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Term ID
Corrected Pval
Fraction Complex Coverage
Proteins
Term Name
REAC:R-HSA-110320
1.25938591632e-05
0.428571428571
VCP UFD1 NPLOC4
Translesion Synthesis by POLH
CORUM:5685
6.1565588648e-05
0.285714285714
VCP UFD1
Membrane protein complex (VCP, UFD1L, SEC61B)
REAC:R-HSA-110313
0.000109213310364
0.428571428571
VCP UFD1 NPLOC4
Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template
CORUM:6280
0.000123103089524
0.285714285714
UFD1 NPLOC4
NUB1L-UFD1-NPL4-NEDD8 complex
GO:0034098
0.0001882019462
0.428571428571
VCP UFD1 NPLOC4
VCP-NPL4-UFD1 AAA ATPase complex
REAC:R-HSA-73893
0.000209532838622
0.428571428571
VCP UFD1 NPLOC4
DNA Damage Bypass
KEGG:04141
0.00211181505065
0.428571428571
VCP UFD1 NPLOC4
Protein processing in endoplasmic reticulum
REAC:R-HSA-9755511
0.0023257157346
0.428571428571
VCP UFD1 NPLOC4
KEAP1-NFE2L2 pathway
GO:0030970
0.00979189312029
0.428571428571
VCP UFD1 NPLOC4
retrograde protein transport, ER to cytosol
GO:1903513
0.00979189312029
0.428571428571
VCP UFD1 NPLOC4
endoplasmic reticulum to cytosol transport
Showing 1 to 10 of 14 entries
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Edges
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Protein 1
Protein 2
Score
?
ProteomeHD
?
Interface Overlap
?
Evidence
?
UFD1
NPLOC4
1.0
0.738
bioplex3_HEK293 bioplex_WMM Guru bioplex3_WMM youn_WMM Malo bioplex3_HCT116 gupta_WMM fraction
UFD1
VCP
0.992
0.582
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM
NPLOC4
VCP
0.976
0.712
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM boldt_WMM treiber_WMM
TMEM31
VCP
0.974
bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only
DEGS1
NPLOC4
0.965
0.06
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM
TMEM31
NPLOC4
0.963
bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only
DEGS1
UFD1
0.936
0.032
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM
TMEM62
NPLOC4
0.923
0.086
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116
TMEM62
VCP
0.919
0.146
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116
FADS1
DEGS1
0.894
0.07
bioplex_WMM bioplex3_WMM WMM_only
Showing 1 to 10 of 18 entries
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Related Complexes
Genename
Complexes
UFD1
huMAP3_03191.1
huMAP3_10598.1
huMAP3_13609.1
huMAP3_15201.1
DEGS1
huMAP3_01234.1
huMAP3_03191.1
huMAP3_06004.1
huMAP3_06937.1
huMAP3_10598.1
huMAP3_13609.1
TMEM31
huMAP3_02158.1
huMAP3_05064.1
huMAP3_05667.1
huMAP3_08012.1
huMAP3_09656.1
huMAP3_11071.1
huMAP3_13609.1
huMAP3_13725.1
NPLOC4
huMAP3_03191.1
huMAP3_10598.1
huMAP3_13609.1
TMEM62
huMAP3_02853.1
huMAP3_09769.1
huMAP3_13609.1
huMAP3_14187.1
VCP
huMAP3_03718.1
huMAP3_05058.1
huMAP3_10598.1
huMAP3_13035.1
huMAP3_13609.1
huMAP3_14974.1
FADS1
huMAP3_01233.1
huMAP3_03746.1
huMAP3_05553.1
huMAP3_13609.1