hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_13618.1
Complex Portal: CPX-21449
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| DENND6B | Protein DENND6B (DENN domain-containing protein 6B) | 3 | UniProt NCBI |
| RPS6KC1 | Ribosomal protein S6 kinase delta-1 (S6K-delta-1) (EC 2.7.11.1) (52 kDa ribosomal protein S6 kinase) (Ribosomal S6 kinase-like protein with two PSK domains 118 kDa protein) (SPHK1-binding protein) | 5 | UniProt NCBI |
| DENND6A | Protein DENND6A (DENN domain-containing protein 6A) | 4 | UniProt NCBI |
| PLEKHH1 | Pleckstrin homology domain-containing family H member 1 (PH domain-containing family H member 1) | 3 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-8876198 | 0.0329793636325 | 0.5 | DENND6B DENND6A | RAB GEFs exchange GTP for GDP on RABs |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| RPS6KC1 | DENND6A | 0.995 | 0.108 | hein_WMM bioplex3_HEK293 bioplex3_WMM hein () | |
| DENND6B | DENND6A | 0.958 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| DENND6A | PLEKHH1 | 0.833 | bioplex3_WMM WMM_only | ||
| DENND6B | RPS6KC1 | 0.415 | bioplex3_WMM WMM_only |
Related Complexes