hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_13651.1
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| FGF11 | Fibroblast growth factor 11 (FGF-11) (Fibroblast growth factor homologous factor 3) (FHF-3) | 4 | UniProt NCBI |
| FAM193A | Protein FAM193A (Protein IT14) | 3 | UniProt NCBI |
| SCN5A | Sodium channel protein type 5 subunit alpha (Sodium channel protein cardiac muscle subunit alpha) (Sodium channel protein type V subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.5) (hH1) | 5 | UniProt NCBI |
| PIAS2 | E3 SUMO-protein ligase PIAS2 (EC 2.3.2.-) (Androgen receptor-interacting protein 3) (ARIP3) (DAB2-interacting protein) (DIP) (E3 SUMO-protein transferase PIAS2) (Msx-interacting zinc finger protein) (Miz1) (PIAS-NY protein) (Protein inhibitor of activated STAT x) (Protein inhibitor of activated STAT2) | 5 | UniProt NCBI |
| GPATCH2 | G patch domain-containing protein 2 | 5 | UniProt NCBI |
| FGF12 | Fibroblast growth factor 12 (FGF-12) (Fibroblast growth factor homologous factor 1) (FHF-1) (Myocyte-activating factor) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-5576892 | 1.42587173715e-05 | 0.5 | FGF12 FGF11 SCN5A | Phase 0 - rapid depolarisation |
| REAC:R-HSA-5576891 | 0.000689296551176 | 0.5 | FGF12 FGF11 SCN5A | Cardiac conduction |
| REAC:R-HSA-397014 | 0.00380890170895 | 0.5 | FGF12 FGF11 SCN5A | Muscle contraction |
| WP:WP3931 | 0.0489911417376 | 0.333333333333 | FGF12 FGF11 | Embryonic stem cell pluripotency pathways |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| FGF11 | SCN5A | 0.989 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| GPATCH2 | FGF11 | 0.988 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| FGF12 | PIAS2 | 0.985 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| FAM193A | FGF11 | 0.985 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| FGF12 | GPATCH2 | 0.984 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| FGF12 | SCN5A | 0.973 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| FAM193A | FGF12 | 0.955 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| PIAS2 | GPATCH2 | 0.415 | 0.126 | bioplex3_WMM WMM_only |
| PIAS2 | SCN5A | 0.415 | 0.086 | bioplex3_WMM WMM_only |
| FAM193A | PIAS2 | 0.356 | 0.202 | bioplex3_WMM youn_WMM WMM_only |
| GPATCH2 | SCN5A | 0.079 | 0.094 | bioplex3_WMM WMM_only |
| FAM193A | GPATCH2 | 0.079 | 0.092 | bioplex3_WMM WMM_only |
| FAM193A | SCN5A | 0.076 | 0.126 | bioplex3_WMM youn_WMM WMM_only |
Related Complexes