hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_13688.1

Confidence: Medium

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Genename	Protein Name	Uniprot Annotation Score	Links
AIMP1	Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 (Multisynthase complex auxiliary component p43) [Cleaved into: Endothelial monocyte-activating polypeptide 2 (EMAP-2) (Endothelial monocyte-activating polypeptide II) (EMAP-II) (Small inducible cytokine subfamily E member 1)]	5	UniProt NCBI
AIMP2	Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 (Multisynthase complex auxiliary component p38) (Protein JTV-1)	5	UniProt NCBI
DARS1	Aspartate--tRNA ligase, cytoplasmic (EC 6.1.1.12) (Aspartyl-tRNA synthetase) (AspRS) (Cell proliferation-inducing gene 40 protein)	5	UniProt NCBI
EEF1E1	Eukaryotic translation elongation factor 1 epsilon-1 (Aminoacyl tRNA synthetase complex-interacting multifunctional protein 3) (Elongation factor p18) (Multisynthase complex auxiliary component p18)	5	UniProt NCBI
EPRS1	Bifunctional glutamate/proline--tRNA ligase (Bifunctional aminoacyl-tRNA synthetase) (Cell proliferation-inducing gene 32 protein) (Glutamatyl-prolyl-tRNA synthetase) [Includes: Glutamate--tRNA ligase (EC 6.1.1.17) (Glutamyl-tRNA synthetase) (GluRS); Proline--tRNA ligase (EC 6.1.1.15) (Prolyl-tRNA synthetase)]	5	UniProt NCBI
IARS1	Isoleucine--tRNA ligase, cytoplasmic (EC 6.1.1.5) (Isoleucyl-tRNA synthetase) (IRS) (IleRS)	5	UniProt NCBI
KARS1	Lysine--tRNA ligase (EC 2.7.7.-) (EC 6.1.1.6) (Lysyl-tRNA synthetase) (LysRS)	5	UniProt NCBI
LARS1	Leucine--tRNA ligase, cytoplasmic (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS) (cLRS)	5	UniProt NCBI
MARS1	Methionine--tRNA ligase, cytoplasmic (EC 6.1.1.10) (Methionyl-tRNA synthetase) (MetRS)	5	UniProt NCBI
QARS1	Glutamine--tRNA ligase (EC 6.1.1.18) (Glutaminyl-tRNA synthetase) (GlnRS)	5	UniProt NCBI

Showing 1 to 10 of 14 entries

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Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
CORUM:3040	3.28665753178e-32	0.833333333333	MARS1 KARS1 AIMP1 EEF1E1 RARS1 LARS1 IARS1 EPRS1 QARS1 AIMP2	Multisynthetase complex
GO:0017101	2.97142578029e-28	0.833333333333	MARS1 KARS1 AIMP1 EEF1E1 RARS1 LARS1 IARS1 EPRS1 QARS1 AIMP2	aminoacyl-tRNA synthetase multienzyme complex
REAC:R-HSA-379716	2.87465324335e-25	0.833333333333	MARS1 KARS1 AIMP1 EEF1E1 RARS1 LARS1 IARS1 EPRS1 QARS1 AIMP2	Cytosolic tRNA aminoacylation
REAC:R-HSA-379724	2.15188977692e-22	0.833333333333	MARS1 KARS1 AIMP1 EEF1E1 RARS1 LARS1 IARS1 EPRS1 QARS1 AIMP2	tRNA Aminoacylation
REAC:R-HSA-2408522	7.47279609189e-18	0.833333333333	MARS1 KARS1 AIMP1 EEF1E1 RARS1 LARS1 IARS1 EPRS1 QARS1 AIMP2	Selenoamino acid metabolism
KEGG:00970	7.17879682652e-17	0.666666666667	MARS1 KARS1 IARS1 TARS3 RARS1 EPRS1 QARS1 LARS1	Aminoacyl-tRNA biosynthesis
GO:0006418	2.3318613891e-14	0.666666666667	MARS1 KARS1 IARS1 TARS3 RARS1 EPRS1 QARS1 LARS1	tRNA aminoacylation for protein translation
GO:0004812	2.93291672476e-14	0.666666666667	MARS1 KARS1 IARS1 TARS3 RARS1 EPRS1 QARS1 LARS1	aminoacyl-tRNA ligase activity
GO:0016875	2.93291672476e-14	0.666666666667	MARS1 KARS1 IARS1 TARS3 RARS1 EPRS1 QARS1 LARS1	ligase activity, forming carbon-oxygen bonds
GO:0043039	4.55268726084e-14	0.666666666667	MARS1 KARS1 IARS1 TARS3 RARS1 EPRS1 QARS1 LARS1	tRNA aminoacylation

Showing 1 to 10 of 128 entries

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Protein 1	Protein 2	Score	ProteomeHD
RARS1	DARS1	1.0	0.506
IARS1	DARS1	1.0	0.488
LARS1	MARS1	1.0	0.788
QARS1	RARS1	1.0	0.646
KARS1	AIMP2	1.0	0.644
IARS1	EPRS1	1.0	0.95
RARS1	IARS1	1.0	0.538
QARS1	DARS1	1.0	0.508
LARS1	EPRS1	1.0	0.864
QARS1	MARS1	1.0	0.424

Showing 1 to 10 of 91 entries

Related Complexes

Genename	Complexes
TARS1	huMAP3_02637.1 huMAP3_08294.1 huMAP3_09382.1 huMAP3_12944.1 huMAP3_13688.1
SDCCAG8	huMAP3_01504.1 huMAP3_06860.1 huMAP3_10122.1 huMAP3_13688.1
AIMP1	huMAP3_02637.1 huMAP3_13688.1
KARS1	huMAP3_02637.1 huMAP3_13688.1
LARS1	huMAP3_02637.1 huMAP3_13688.1
AIMP2	huMAP3_02637.1 huMAP3_13688.1
EEF1E1	huMAP3_02637.1 huMAP3_13688.1
QARS1	huMAP3_02637.1 huMAP3_13688.1
TARS3	huMAP3_02637.1 huMAP3_11280.1 huMAP3_13688.1
RARS1	huMAP3_02637.1 huMAP3_13688.1
IARS1	huMAP3_02637.1 huMAP3_13688.1
MARS1	huMAP3_02637.1 huMAP3_13274.1 huMAP3_13688.1
EPRS1	huMAP3_02637.1 huMAP3_13688.1
DARS1	huMAP3_02637.1 huMAP3_13688.1