hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_13699.1
Complex Portal: CPX-18154
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| LAG3 | Lymphocyte activation gene 3 protein (LAG-3) (CD antigen CD223) [Cleaved into: Secreted lymphocyte activation gene 3 protein (sLAG-3)] | 5 | UniProt NCBI |
| HS3ST3B1 | Heparan sulfate glucosamine 3-O-sulfotransferase 3B1 (EC 2.8.2.30) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3B1) (3-OST-3B) (Heparan sulfate 3-O-sulfotransferase 3B1) (h3-OST-3B) | 5 | UniProt NCBI |
| CD1A | T-cell surface glycoprotein CD1a (T-cell surface antigen T6/Leu-6) (hTa1 thymocyte antigen) (CD antigen CD1a) | 5 | UniProt NCBI |
| CHST11 | Carbohydrate sulfotransferase 11 (EC 2.8.2.5) (Chondroitin 4-O-sulfotransferase 1) (Chondroitin 4-sulfotransferase 1) (C4S-1) (C4ST-1) (C4ST1) | 5 | UniProt NCBI |
| RNF167 | E3 ubiquitin-protein ligase RNF167 (EC 2.3.2.27) (RING finger protein 167) | 5 | UniProt NCBI |
| SSTR5 | Somatostatin receptor type 5 (SS-5-R) (SS5-R) (SS5R) (SST5) | 5 | UniProt NCBI |
| HLA-DPA1 | HLA class II histocompatibility antigen, DP alpha 1 chain (DP(W3)) (DP(W4)) (HLA-SB alpha chain) (MHC class II DP3-alpha) (MHC class II DPA1) | 5 | UniProt NCBI |
| DCBLD1 | Discoidin, CUB and LCCL domain-containing protein 1 | 3 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP5395 | 0.00703705758996 | 0.333333333333 | HS3ST3B1 CHST11 | Glycosaminoglycan synthesis in fibroblasts |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| CHST11 | HLA-DPA1 | 0.968 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| CD1A | HLA-DPA1 | 0.965 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| HLA-DPA1 | RNF167 | 0.96 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| CD1A | RNF167 | 0.945 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| HLA-DPA1 | LAG3 | 0.924 | 0.196 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| HLA-DPA1 | SSTR5 | 0.924 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| HLA-DPA1 | DCBLD1 | 0.913 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| HLA-DPA1 | HS3ST3B1 | 0.842 | 0.114 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| CHST11 | HS3ST3B1 | 0.224 | 0.088 | bioplex_WMM bioplex3_WMM WMM_only | |
| DCBLD1 | HS3ST3B1 | 0.224 | 0.122 | bioplex_WMM bioplex3_WMM WMM_only | |
| CHST11 | DCBLD1 | 0.215 | 0.094 | bioplex_WMM bioplex3_WMM WMM_only | |
| DCBLD1 | RNF167 | 0.198 | 0.112 | bioplex_WMM bioplex3_WMM WMM_only | |
| RNF167 | HS3ST3B1 | 0.164 | 0.066 | bioplex_WMM bioplex3_WMM WMM_only | |
| CHST11 | RNF167 | 0.162 | 0.18 | bioplex_WMM bioplex3_WMM WMM_only | |
| SSTR5 | HS3ST3B1 | 0.043 | bioplex3_WMM WMM_only | ||
| DCBLD1 | SSTR5 | 0.042 | bioplex3_WMM WMM_only | ||
| CHST11 | SSTR5 | 0.042 | bioplex3_WMM WMM_only | ||
| SSTR5 | RNF167 | 0.031 | bioplex3_WMM WMM_only |
Related Complexes