hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_13728.1
Complex Portal: CPX-13019
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| TDRD3 | Tudor domain-containing protein 3 | 5 | UniProt NCBI |
| TOP3B | DNA topoisomerase 3-beta-1 (EC 5.6.2.1) (DNA topoisomerase III beta-1) | 5 | UniProt NCBI |
| KBTBD2 | Kelch repeat and BTB domain-containing protein 2 (BTB and kelch domain-containing protein 1) | 4 | UniProt NCBI |
| SYNGR4 | Synaptogyrin-4 | 2 | UniProt NCBI |
| FXR1 | RNA-binding protein FXR1 (FMR1 autosomal homolog 1) (hFXR1p) | 5 | UniProt NCBI |
| FMR1 | Fragile X messenger ribonucleoprotein 1 (Fragile X messenger ribonucleoprotein) (FMRP) (Protein FMR-1) | 5 | UniProt NCBI |
| MITD1 | MIT domain-containing protein 1 | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:7407 | 2.05265451394e-05 | 0.285714285714 | TDRD3 TOP3B | TOP3B-c complex |
| GO:0140225 | 0.00983221512175 | 0.285714285714 | TDRD3 TOP3B | DNA topoisomerase III-beta-TDRD3 complex |
| GO:0033592 | 0.0294899169624 | 0.285714285714 | FXR1 FMR1 | RNA strand annealing activity |
| GO:0044326 | 0.0294899169624 | 0.285714285714 | FXR1 FMR1 | dendritic spine neck |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| TOP3B | TDRD3 | 0.999 | 0.425307692308 | hein_WMM youn () bioplex3_HEK293 Guru bioplex3_WMM youn_WMM gupta_WMM fraction | |
| FXR1 | FMR1 | 0.998 | 0.446 | hein_WMM youn () bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM treiber_WMM | |
| TOP3B | FMR1 | 0.986 | 0.336 | hein_WMM youn () bioplex3_WMM youn_WMM treiber_WMM WMM_only | |
| TOP3B | FXR1 | 0.985 | 0.2225 | hein_WMM youn () bioplex3_HEK293 bioplex3_WMM youn_WMM gupta_WMM fraction treiber_WMM | |
| MITD1 | TOP3B | 0.95 | 0.211307692308 | hein_WMM bioplex3_WMM WMM_only | |
| KBTBD2 | FMR1 | 0.861 | 0.118 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| FXR1 | SYNGR4 | 0.853 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| TDRD3 | FMR1 | 0.738 | 0.114 | hein_WMM youn () bioplex3_WMM youn_WMM gupta_WMM fraction | |
| TDRD3 | FXR1 | 0.552 | 0.092 | hein_WMM youn () bioplex3_WMM youn_WMM gupta_WMM WMM_only | |
| KBTBD2 | FXR1 | 0.126 | 0.032 | bioplex_WMM bioplex3_WMM WMM_only | |
| MITD1 | FMR1 | 0.022 | 0.126 | bioplex3_WMM WMM_only | |
| MITD1 | FXR1 | 0.019 | 0.086 | bioplex3_WMM WMM_only |
Related Complexes