hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_13743.1
Complex Portal: CPX-25633
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| PRPF40A | Pre-mRNA-processing factor 40 homolog A (Fas ligand-associated factor 1) (Formin-binding protein 11) (Formin-binding protein 3) (Huntingtin yeast partner A) (Huntingtin-interacting protein 10) (HIP-10) (Huntingtin-interacting protein A) (Renal carcinoma antigen NY-REN-6) | 5 | UniProt NCBI |
| PUF60 | Poly(U)-binding-splicing factor PUF60 (60 kDa poly(U)-binding-splicing factor) (FUSE-binding protein-interacting repressor) (FBP-interacting repressor) (Ro-binding protein 1) (RoBP1) (Siah-binding protein 1) (Siah-BP1) | 5 | UniProt NCBI |
| BICRA | BRD4-interacting chromatin-remodeling complex-associated protein (Glioma tumor suppressor candidate region gene 1 protein) | 5 | UniProt NCBI |
| RBM25 | RNA-binding protein 25 (Arg/Glu/Asp-rich protein of 120 kDa) (RED120) (Protein S164) (RNA-binding motif protein 25) (RNA-binding region-containing protein 7) | 5 | UniProt NCBI |
| SLC30A4 | Probable proton-coupled zinc antiporter SLC30A4 (Solute carrier family 30 member 4) (Zinc transporter 4) (ZnT-4) | 5 | UniProt NCBI |
| SFSWAP | Splicing factor, suppressor of white-apricot homolog (Splicing factor, arginine/serine-rich 8) (Suppressor of white apricot protein homolog) | 4 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:03040 | 0.000620541886073 | 0.5 | PRPF40A PUF60 RBM25 | Spliceosome |
| CORUM:351 | 0.00192068311585 | 0.5 | PRPF40A PUF60 RBM25 | Spliceosome |
| REAC:R-HSA-72163 | 0.00913908174037 | 0.5 | PRPF40A PUF60 RBM25 | mRNA Splicing - Major Pathway |
| REAC:R-HSA-72172 | 0.0101216651073 | 0.5 | PRPF40A PUF60 RBM25 | mRNA Splicing |
| REAC:R-HSA-72203 | 0.0229811698012 | 0.5 | PRPF40A PUF60 RBM25 | Processing of Capped Intron-Containing Pre-mRNA |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| RBM25 | PRPF40A | 1.0 | hein_WMM bioplex3_HEK293 bioplex_WMM Guru bioplex3_WMM boldt youn_WMM gupta_WMM fraction boldt_WMM treiber_WMM | ||
| RBM25 | SLC30A4 | 0.99 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | ||
| BICRA | PRPF40A | 0.979 | hein_WMM bioplex_WMM bioplex3_WMM youn_WMM WMM_only | ||
| PUF60 | PRPF40A | 0.968 | bioplex3_HEK293 bioplex () bioplex_WMM Guru bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM fraction treiber_WMM | ||
| RBM25 | BICRA | 0.964 | 0.106 | hein_WMM bioplex_WMM bioplex3_WMM youn_WMM WMM_only | |
| PUF60 | RBM25 | 0.963 | 0.694 |
structurally_consistent (O95232)
|
bioplex3_HEK293 bioplex_WMM Guru bioplex3_WMM youn_WMM gupta_WMM fraction treiber_WMM |
| BICRA | SFSWAP | 0.948 | 0.104 | hein_WMM bioplex3_WMM youn_WMM WMM_only | |
| PRPF40A | SFSWAP | 0.921 | hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM WMM_only | ||
| SLC30A4 | PRPF40A | 0.917 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| RBM25 | SFSWAP | 0.857 | 0.206 | hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM WMM_only | |
| PUF60 | SFSWAP | 0.086 | 0.193333333333 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 WMM_only | |
| PUF60 | BICRA | 0.05 | 0.152 | bioplex3_WMM youn_WMM WMM_only | |
| PUF60 | SLC30A4 | 0.002 | bioplex3_HEK293 bioplex () bioplex3_HCT116 |
Related Complexes