hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_13747.1
Complex Portal: CPX-15228
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| DHDDS | Dehydrodolichyl diphosphate synthase complex subunit DHDDS (EC 2.5.1.87) (Cis-isoprenyltransferase) (CIT) (Cis-IPTase) (Cis-prenyltransferase subunit hCIT) (Epididymis tissue protein Li 189m) | 5 | UniProt NCBI |
| IGFBP6 | Insulin-like growth factor-binding protein 6 (IBP-6) (IGF-binding protein 6) (IGFBP-6) | 5 | UniProt NCBI |
| MPST | 3-mercaptopyruvate sulfurtransferase (MST) (EC 2.8.1.2) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:04122 | 0.0190017961688 | 0.5 | MPST | Sulfur relay system |
| KEGG:00920 | 0.0237506195141 | 0.5 | MPST | Sulfur metabolism |
| WP:WP2333 | 0.049750157242 | 0.5 | MPST | Trans sulfuration pathway |
| REAC:R-HSA-4755609 | 0.0499419797295 | 0.5 | DHDDS | Defective DHDDS causes RP59 |
| CORUM:6238 | 0.0499419797295 | 0.5 | DHDDS | DHDDS-NUS1 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| DHDDS | IGFBP6 | 0.97 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| IGFBP6 | MPST | 0.851 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | ||
| DHDDS | MPST | 0.033 | 0.054 | bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only |
Related Complexes
| Genename | Complexes |
|---|---|
| DHDDS | huMAP3_04340.1 huMAP3_09887.1 huMAP3_13395.1 huMAP3_13458.1 huMAP3_13747.1 |
| IGFBP6 | huMAP3_09887.1 huMAP3_13747.1 |
| MPST | huMAP3_11638.1 huMAP3_12895.1 huMAP3_13747.1 |