hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_13759.1
Complex Portal: CPX-25477
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| FBN1 | Fibrillin-1 [Cleaved into: Asprosin] | 5 | UniProt NCBI |
| ZXDB | Zinc finger X-linked protein ZXDB | 4 | UniProt NCBI |
| NTN5 | Netrin-5 (Netrin-1-like protein) | 3 | UniProt NCBI |
| FBLN5 | Fibulin-5 (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance) (Urine p50 protein) (UP50) | 5 | UniProt NCBI |
| FOXG1 | Forkhead box protein G1 (Brain factor 1) (BF-1) (BF1) (Brain factor 2) (BF-2) (BF2) (hBF-2) (Forkhead box protein G1A) (Forkhead box protein G1B) (Forkhead box protein G1C) (Forkhead-related protein FKHL1) (HFK1) (Forkhead-related protein FKHL2) (HFK2) (Forkhead-related protein FKHL3) (HFK3) | 5 | UniProt NCBI |
| TKTL2 | Transketolase-like protein 2 (EC 2.2.1.1) | 4 | UniProt NCBI |
| HOXB3 | Homeobox protein Hox-B3 (Homeobox protein Hox-2.7) (Homeobox protein Hox-2G) | 5 | UniProt NCBI |
| ZIC3 | Zinc finger protein ZIC 3 (Zinc finger protein 203) (Zinc finger protein of the cerebellum 3) | 5 | UniProt NCBI |
| ZNF737 | Zinc finger protein 737 (Zinc finger protein 102) | 3 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:6914 | 2.73623797451e-05 | 0.222222222222 | FBN1 FBLN5 | ELN-FBLN5-FBN1 complex |
| REAC:R-HSA-2129379 | 0.032153801025 | 0.222222222222 | FBN1 FBLN5 | Molecules associated with elastic fibres |
| HPA:0471432 | 0.036644700733 | 0.222222222222 | FBN1 FBLN5 | skin 2; extracellular matrix[>=Medium] |
| REAC:R-HSA-1566948 | 0.0497823629923 | 0.222222222222 | FBN1 FBLN5 | Elastic fibre formation |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| FBN1 | NTN5 | 0.985 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| FBLN5 | ZIC3 | 0.936 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| FBLN5 | ZXDB | 0.932 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| FBLN5 | ZNF737 | 0.927 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| FOXG1 | FBLN5 | 0.899 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| FBN1 | FBLN5 | 0.889 | 0.314 | bioplex_WMM bioplex3_WMM WMM_only | |
| FBLN5 | TKTL2 | 0.884 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| FBLN5 | NTN5 | 0.884 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| FBLN5 | HOXB3 | 0.805 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| FOXG1 | ZIC3 | 0.415 | bioplex3_WMM WMM_only | ||
| FOXG1 | ZNF737 | 0.415 | bioplex3_WMM WMM_only | ||
| ZIC3 | ZNF737 | 0.415 | bioplex3_WMM WMM_only |
Related Complexes