hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_13794.1
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| PLCG1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 (EC 3.1.4.11) (PLC-148) (Phosphoinositide phospholipase C-gamma-1) (Phospholipase C-II) (PLC-II) (Phospholipase C-gamma-1) (PLC-gamma-1) | 5 | UniProt NCBI |
| GAS2L2 | GAS2-like protein 2 (GAS2-related protein on chromosome 17) (Growth arrest-specific protein 2-like 2) | 5 | UniProt NCBI |
| RNF175 | RING finger protein 175 | 3 | UniProt NCBI |
| MAPRE3 | Microtubule-associated protein RP/EB family member 3 (EB1 protein family member 3) (EBF3) (End-binding protein 3) (EB3) (RP3) | 5 | UniProt NCBI |
| MAPRE2 | Microtubule-associated protein RP/EB family member 2 (APC-binding protein EB2) (End-binding protein 2) (EB2) | 5 | UniProt NCBI |
| MAPRE1 | Microtubule-associated protein RP/EB family member 1 (APC-binding protein EB1) (End-binding protein 1) (EB1) | 5 | UniProt NCBI |
| GAS2L1 | GAS2-like protein 1 (GAS2-related protein on chromosome 22) (Growth arrest-specific protein 2-like 1) | 5 | UniProt NCBI |
| GNE | Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase (UDP-GlcNAc-2-epimerase/ManAc kinase) [Includes: UDP-N-acetylglucosamine 2-epimerase (hydrolyzing) (EC 3.2.1.183) (UDP-GlcNAc-2-epimerase) (Uridine diphosphate-N-acetylglucosamine-2-epimerase); N-acetylmannosamine kinase (EC 2.7.1.60) (ManAc kinase)] | 5 | UniProt NCBI |
| ZDHHC1 | Palmitoyltransferase ZDHHC1 (EC 2.3.1.225) (DHHC domain-containing cysteine-rich protein 1) (Zinc finger DHHC domain-containing protein 1) (DHHC-1) (Zinc finger protein 377) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0035372 | 2.26671487374e-09 | 0.555555555556 | GAS2L2 GAS2L1 MAPRE3 MAPRE1 MAPRE2 | protein localization to microtubule |
| GO:0035371 | 4.8014338698e-08 | 0.555555555556 | GAS2L2 GAS2L1 MAPRE3 MAPRE1 MAPRE2 | microtubule plus-end |
| GO:1990752 | 3.13612595242e-07 | 0.555555555556 | GAS2L2 GAS2L1 MAPRE3 MAPRE1 MAPRE2 | microtubule end |
| GO:0072698 | 9.57006592588e-07 | 0.555555555556 | GAS2L2 GAS2L1 MAPRE3 MAPRE1 MAPRE2 | protein localization to microtubule cytoskeleton |
| GO:0044380 | 1.22120697132e-06 | 0.555555555556 | GAS2L2 GAS2L1 MAPRE3 MAPRE1 MAPRE2 | protein localization to cytoskeleton |
| GO:0031110 | 2.35552553862e-05 | 0.555555555556 | GAS2L2 GAS2L1 MAPRE3 MAPRE1 MAPRE2 | regulation of microtubule polymerization or depolymerization |
| GO:0031109 | 0.000148523354604 | 0.555555555556 | GAS2L2 GAS2L1 MAPRE3 MAPRE1 MAPRE2 | microtubule polymerization or depolymerization |
| GO:0070507 | 0.000315597499132 | 0.555555555556 | GAS2L2 GAS2L1 MAPRE3 MAPRE1 MAPRE2 | regulation of microtubule cytoskeleton organization |
| GO:0032886 | 0.0024864095219 | 0.555555555556 | GAS2L2 GAS2L1 MAPRE3 MAPRE1 MAPRE2 | regulation of microtubule-based process |
| GO:0008017 | 0.00342863407187 | 0.555555555556 | GAS2L2 GAS2L1 MAPRE3 MAPRE1 MAPRE2 | microtubule binding |
| GO:0051010 | 0.00778531456229 | 0.333333333333 | MAPRE2 MAPRE3 MAPRE1 | microtubule plus-end binding |
| GO:0005874 | 0.0127581775757 | 0.555555555556 | GAS2L2 GAS2L1 MAPRE3 MAPRE1 MAPRE2 | microtubule |
| GO:0015631 | 0.0194221729068 | 0.555555555556 | GAS2L2 GAS2L1 MAPRE3 MAPRE1 MAPRE2 | tubulin binding |
| GO:0051233 | 0.0478559415828 | 0.333333333333 | MAPRE2 MAPRE3 MAPRE1 | spindle midzone |
| CORUM:2960 | 0.0499842271994 | 0.111111111111 | PLCG1 | SLP-76-PLC-gamma-1-ITK complex, alpha-TCR stimulated |
| CORUM:2961 | 0.0499842271994 | 0.111111111111 | PLCG1 | SLP-76-PLC-gamma-1-VAV complex, alpha-TCR stimulated |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| MAPRE1 | MAPRE3 | 1.0 | 0.076 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt bioplex3_HCT116 gupta_WMM boldt_WMM |
| MAPRE2 | MAPRE1 | 1.0 | 0.104 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt youn_WMM bioplex3_HCT116 gupta_WMM fraction boldt_WMM |
| MAPRE3 | GAS2L1 | 1.0 | 0.112 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| GAS2L2 | MAPRE3 | 1.0 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| MAPRE1 | GAS2L1 | 0.999 | 0.078 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM hein () bioplex3_HCT116 |
| GNE | GAS2L2 | 0.999 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| MAPRE2 | MAPRE3 | 0.998 | 0.104 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 gupta_WMM WMM_only |
| MAPRE2 | RNF175 | 0.992 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| GAS2L2 | MAPRE1 | 0.991 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| MAPRE2 | GAS2L1 | 0.979 | 0.048 | bioplex3_WMM bioplex3_HCT116 WMM_only |
| MAPRE2 | GAS2L2 | 0.918 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| PLCG1 | GAS2L1 | 0.916 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| MAPRE1 | ZDHHC1 | 0.837 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| GNE | MAPRE3 | 0.476 | 0.064 | bioplex3_WMM WMM_only |
| GNE | MAPRE1 | 0.357 | 0.146 | bioplex3_WMM WMM_only |
| PLCG1 | MAPRE3 | 0.133 | bioplex_WMM bioplex3_WMM WMM_only | |
| MAPRE2 | GNE | 0.064 | 0.032 | bioplex3_WMM WMM_only |
| PLCG1 | MAPRE1 | 0.036 | bioplex_WMM bioplex3_WMM WMM_only | |
| MAPRE2 | PLCG1 | 0.011 | bioplex3_WMM WMM_only | |
| GNE | PLCG1 | 0.008 | fraction |
Related Complexes