hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_13804.1

Confidence: Medium

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Genename	Protein Name	Uniprot Annotation Score	Links
ALK	ALK tyrosine kinase receptor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD antigen CD246)	5	UniProt NCBI
ERAP1	Endoplasmic reticulum aminopeptidase 1 (EC 3.4.11.-) (ARTS-1) (Adipocyte-derived leucine aminopeptidase) (A-LAP) (Aminopeptidase PILS) (Puromycin-insensitive leucyl-specific aminopeptidase) (PILS-AP) (Type 1 tumor necrosis factor receptor shedding aminopeptidase regulator)	5	UniProt NCBI

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Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
HP:0001482	0.0105293899166	1.0	ERAP1 ALK	Subcutaneous nodule
HP:0200036	0.0176036635704	1.0	ERAP1 ALK	Skin nodule
REAC:R-HSA-9717264	0.0249718442457	0.5	ALK	ASP-3026-resistant ALK mutants
REAC:R-HSA-9700649	0.0249718442457	0.5	ALK	Drug resistance of ALK mutants
REAC:R-HSA-9717301	0.0249718442457	0.5	ALK	NVP-TAE684-resistant ALK mutants
REAC:R-HSA-9717316	0.0249718442457	0.5	ALK	alectinib-resistant ALK mutants
REAC:R-HSA-9717319	0.0249718442457	0.5	ALK	brigatinib-resistant ALK mutants
REAC:R-HSA-9717323	0.0249718442457	0.5	ALK	ceritinib-resistant ALK mutants
REAC:R-HSA-9717326	0.0249718442457	0.5	ALK	crizotinib-resistant ALK mutants
REAC:R-HSA-9717329	0.0249718442457	0.5	ALK	lorlatinib-resistant ALK mutants

Showing 1 to 10 of 11 entries

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Protein 1	Protein 2	Score	ProteomeHD	Evidence
ERAP1	ALK	0.905		bioplex3_HEK293 bioplex3_WMM WMM_only

Showing 1 to 1 of 1 entries

Related Complexes

Genename	Complexes
ERAP1	huMAP3_03021.1 huMAP3_13804.1
ALK	huMAP3_12321.1 huMAP3_13555.1 huMAP3_13804.1 huMAP3_13917.1 huMAP3_14478.1 huMAP3_14611.1 huMAP3_14845.1