hu.MAP 3.0: Complex View

Genename	Protein Name	Uniprot Annotation Score	Links
ERAP1	Endoplasmic reticulum aminopeptidase 1 (EC 3.4.11.-) (ARTS-1) (Adipocyte-derived leucine aminopeptidase) (A-LAP) (Aminopeptidase PILS) (Puromycin-insensitive leucyl-specific aminopeptidase) (PILS-AP) (Type 1 tumor necrosis factor receptor shedding aminopeptidase regulator)	5	UniProt NCBI
ALK	ALK tyrosine kinase receptor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD antigen CD246)	5	UniProt NCBI

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
HP:0001482	0.0105293899166	1.0	ALK ERAP1	Subcutaneous nodule
HP:0200036	0.0176036635704	1.0	ALK ERAP1	Skin nodule
REAC:R-HSA-9717264	0.0249718442457	0.5	ALK	ASP-3026-resistant ALK mutants
REAC:R-HSA-9700649	0.0249718442457	0.5	ALK	Drug resistance of ALK mutants
REAC:R-HSA-9717301	0.0249718442457	0.5	ALK	NVP-TAE684-resistant ALK mutants
REAC:R-HSA-9717316	0.0249718442457	0.5	ALK	alectinib-resistant ALK mutants
REAC:R-HSA-9717319	0.0249718442457	0.5	ALK	brigatinib-resistant ALK mutants
REAC:R-HSA-9717323	0.0249718442457	0.5	ALK	ceritinib-resistant ALK mutants
REAC:R-HSA-9717326	0.0249718442457	0.5	ALK	crizotinib-resistant ALK mutants
REAC:R-HSA-9717329	0.0249718442457	0.5	ALK	lorlatinib-resistant ALK mutants
CORUM:5370	0.0249718442457	0.5	ERAP1	ERAP1-ERAP2 complex

Protein 1	Protein 2	Score	ProteomeHD	Interface Overlap	Evidence
ERAP1	ALK	0.905			bioplex3_HEK293 bioplex3_WMM WMM_only

Genename	Complexes
ERAP1	huMAP3_03021.1 huMAP3_13804.1
ALK	huMAP3_12321.1 huMAP3_13555.1 huMAP3_13804.1 huMAP3_13917.1 huMAP3_14478.1 huMAP3_14611.1 huMAP3_14845.1