hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_13805.1

Complex Portal: CPX-21196

Confidence: Medium

Genename	Protein Name	Uniprot Annotation Score	Links
TAS2R7	Taste receptor type 2 member 7 (T2R7) (Taste receptor family B member 4) (TRB4)	4	UniProt NCBI
VPS9D1	VPS9 domain-containing protein 1 (Protein ATP-BL)	5	UniProt NCBI
VPS28	Vacuolar protein sorting-associated protein 28 homolog (H-Vps28) (ESCRT-I complex subunit VPS28)	5	UniProt NCBI
TSG101	Tumor susceptibility gene 101 protein (ESCRT-I complex subunit TSG101)	5	UniProt NCBI
UMAD1	UBAP1-MVB12-associated (UMA)-domain containing protein 1 (RPA3 antisense RNA 1) (RPA3 opposite strand)	2	UniProt NCBI
CHMP4A	Charged multivesicular body protein 4a (Chromatin-modifying protein 4a) (CHMP4a) (SNF7 homolog associated with Alix-2) (SNF7-1) (hSnf-1) (Vacuolar protein sorting-associated protein 32-1) (Vps32-1) (hVps32-1)	5	UniProt NCBI
CD2AP	CD2-associated protein (Adapter protein CMS) (Cas ligand with multiple SH3 domains)	5	UniProt NCBI
CAPN7	Calpain-7 (EC 3.4.22.-) (PalB homolog) (PalBH)	5	UniProt NCBI
PDCD6IP	Programmed cell death 6-interacting protein (PDCD6-interacting protein) (ALG-2-interacting protein 1) (ALG-2-interacting protein X) (Hp95)	5	UniProt NCBI
CHMP2A	Charged multivesicular body protein 2a (Chromatin-modifying protein 2a) (CHMP2a) (Putative breast adenocarcinoma marker BC-2) (Vacuolar protein sorting-associated protein 2-1) (Vps2-1) (hVps2-1)	5	UniProt NCBI
VPS37A	Vacuolar protein sorting-associated protein 37A (hVps37A) (ESCRT-I complex subunit VPS37A) (Hepatocellular carcinoma-related protein 1)	5	UniProt NCBI
CHMP3	Charged multivesicular body protein 3 (Chromatin-modifying protein 3) (Neuroendocrine differentiation factor) (Vacuolar protein sorting-associated protein 24) (hVps24)	5	UniProt NCBI
CHMP1A	Charged multivesicular body protein 1a (Chromatin-modifying protein 1a) (CHMP1a) (Vacuolar protein sorting-associated protein 46-1) (Vps46-1) (hVps46-1)	5	UniProt NCBI
MVB12B	Multivesicular body subunit 12B (ESCRT-I complex subunit MVB12B) (Protein FAM125B)	5	UniProt NCBI
CHMP2B	Charged multivesicular body protein 2b (CHMP2.5) (Chromatin-modifying protein 2b) (CHMP2b) (Vacuolar protein sorting-associated protein 2-2) (Vps2-2) (hVps2-2)	5	UniProt NCBI
PSPN	Persephin (PSP)	4	UniProt NCBI
IST1	IST1 homolog (hIST1) (Charged multivesicular body protein 8) (CHMP8) (Putative MAPK-activating protein PM28)	5	UniProt NCBI
BAZ2B	Bromodomain adjacent to zinc finger domain protein 2B (hWALp4)	5	UniProt NCBI
MVB12A	Multivesicular body subunit 12A (CIN85/CD2AP family-binding protein) (ESCRT-I complex subunit MVB12A) (Protein FAM125A)	5	UniProt NCBI
PTPN23	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14)	5	UniProt NCBI
CHMP4B	Charged multivesicular body protein 4b (Chromatin-modifying protein 4b) (CHMP4b) (SNF7 homolog associated with Alix 1) (SNF7-2) (hSnf7-2) (Vacuolar protein sorting-associated protein 32-2) (Vps32-2) (hVps32-2)	5	UniProt NCBI
VPS37B	Vacuolar protein sorting-associated protein 37B (hVps37B) (ESCRT-I complex subunit VPS37B)	5	UniProt NCBI
CHMP5	Charged multivesicular body protein 5 (Chromatin-modifying protein 5) (SNF7 domain-containing protein 2) (Vacuolar protein sorting-associated protein 60) (Vps60) (hVps60)	5	UniProt NCBI
SPAST	Spastin (EC 5.6.1.1) (Spastic paraplegia 4 protein)	5	UniProt NCBI
VPS37C	Vacuolar protein sorting-associated protein 37C (hVps37C) (ESCRT-I complex subunit VPS37C)	5	UniProt NCBI
CHMP1B	Charged multivesicular body protein 1b (CHMP1.5) (Chromatin-modifying protein 1b) (CHMP1b) (Vacuolar protein sorting-associated protein 46-2) (Vps46-2) (hVps46-2)	5	UniProt NCBI
MITD1	MIT domain-containing protein 1	5	UniProt NCBI
PDCD6	Programmed cell death protein 6 (Apoptosis-linked gene 2 protein homolog) (ALG-2)	5	UniProt NCBI
GLIS2	Zinc finger protein GLIS2 (GLI-similar 2) (Neuronal Krueppel-like protein)	5	UniProt NCBI
UBAP1	Ubiquitin-associated protein 1 (UBAP-1) (Nasopharyngeal carcinoma-associated gene 20 protein)	5	UniProt NCBI

Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
GO:0036258	6.17252208093e-39	0.6	CHMP2A CHMP5 VPS37A TSG101 MVB12A UBAP1 CHMP1A MVB12B VPS37B VPS37C VPS28 CHMP4A CHMP2B CHMP4B CHMP1B CHMP3 IST1 PDCD6IP	multivesicular body assembly
GO:0036257	1.40976248423e-38	0.6	CHMP2A CHMP5 VPS37A TSG101 MVB12A UBAP1 CHMP1A MVB12B VPS37B VPS37C VPS28 CHMP4A CHMP2B CHMP4B CHMP1B CHMP3 IST1 PDCD6IP	multivesicular body organization
GO:0046755	8.62395473349e-36	0.533333333333	CHMP2A CHMP5 VPS37A TSG101 MVB12A CHMP1A MVB12B VPS37B VPS28 CHMP4A CHMP2B CHMP4B CHMP1B CHMP3 VPS37C PDCD6IP	viral budding
GO:0045324	8.8969185738e-36	0.566666666667	CHMP2A CHMP5 VPS37A TSG101 MVB12A UBAP1 MVB12B PTPN23 VPS28 CHMP4A CHMP2B VPS37B CHMP4B CHMP1B CHMP3 VPS37C CHMP1A	late endosome to vacuole transport
GO:0043162	3.90805610158e-35	0.566666666667	CHMP2A CHMP5 VPS37A TSG101 MVB12A UBAP1 MVB12B PTPN23 VPS28 CHMP4A CHMP2B VPS37B CHMP4B CHMP1B CHMP3 VPS37C CHMP1A	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
GO:0032509	7.80953183474e-35	0.566666666667	CHMP2A CHMP5 VPS37A TSG101 MVB12A UBAP1 MVB12B PTPN23 VPS28 CHMP4A CHMP2B VPS37B CHMP4B CHMP1B CHMP3 VPS37C CHMP1A	endosome transport via multivesicular body sorting pathway
GO:0039702	5.31643267322e-34	0.5	CHMP2A CHMP5 VPS37A TSG101 MVB12A CHMP1A VPS37B VPS28 CHMP4A CHMP2B CHMP4B CHMP1B CHMP3 VPS37C PDCD6IP	viral budding via host ESCRT complex
GO:0071985	2.95450247142e-33	0.566666666667	CHMP2A CHMP5 VPS37A TSG101 MVB12A UBAP1 MVB12B PTPN23 VPS28 CHMP4A CHMP2B VPS37B CHMP4B CHMP1B CHMP3 VPS37C CHMP1A	multivesicular body sorting pathway
REAC:R-HSA-162588	4.02786089834e-33	0.5	CHMP2A CHMP5 VPS37A TSG101 MVB12A UBAP1 MVB12B VPS37B VPS28 CHMP4A CHMP2B CHMP4B CHMP3 VPS37C PDCD6IP	Budding and maturation of HIV virion
GO:0090148	5.04302390994e-33	0.566666666667	CHMP2A SPAST CHMP5 VPS37A TSG101 MVB12A UBAP1 MVB12B VPS37B VPS28 CHMP4A CHMP2B CHMP4B CHMP1B CHMP3 VPS37C CHMP1A	membrane fission
GO:0019068	2.09731157428e-32	0.533333333333	CHMP2A CHMP5 VPS37A TSG101 MVB12A CHMP1A MVB12B VPS37B VPS28 CHMP4A CHMP2B CHMP4B CHMP1B CHMP3 VPS37C PDCD6IP	virion assembly
GO:0036452	1.11549124613e-31	0.5	CHMP2A VPS37A TSG101 MVB12A UBAP1 MVB12B VPS37B VPS28 CHMP4A CHMP2B CHMP4B CHMP1B CHMP3 VPS37C CHMP1A	ESCRT complex
GO:0007032	1.3144333044e-29	0.6	CHMP2A CHMP5 VPS37A TSG101 MVB12A UBAP1 CHMP1A MVB12B VPS37B VPS37C VPS28 CHMP4A CHMP2B CHMP4B CHMP1B CHMP3 IST1 PDCD6IP	endosome organization
REAC:R-HSA-917729	3.06008204877e-29	0.466666666667	CHMP2A VPS37A TSG101 MVB12A UBAP1 MVB12B VPS37B VPS28 CHMP4A CHMP5 CHMP4B CHMP3 VPS37C CHMP2B	Endosomal Sorting Complex Required For Transport (ESCRT)
REAC:R-HSA-9615710	6.25237236085e-26	0.433333333333	CHMP2A VPS37A TSG101 MVB12A UBAP1 MVB12B VPS37B VPS28 CHMP4A CHMP4B CHMP3 VPS37C CHMP2B	Late endosomal microautophagy
GO:0032511	1.40083201565e-23	0.4	VPS37A MVB12A TSG101 UBAP1 MVB12B PTPN23 VPS28 CHMP4A CHMP5 CHMP4B VPS37B VPS37C	late endosome to vacuole transport via multivesicular body sorting pathway
GO:0007034	3.31107811297e-23	0.566666666667	CHMP2A CHMP5 VPS37A TSG101 MVB12A UBAP1 MVB12B PTPN23 VPS28 CHMP4A CHMP2B VPS37B CHMP4B CHMP1B CHMP3 VPS37C CHMP1A	vacuolar transport
KEGG:04144	8.40323189814e-22	0.566666666667	CHMP2A CHMP5 VPS37A TSG101 MVB12A CHMP1A MVB12B VPS37B VPS37C VPS28 CHMP4A CHMP2B CHMP4B CHMP1B CHMP3 IST1 PDCD6IP	Endocytosis
GO:0016050	3.04260339997e-21	0.633333333333	CHMP2A CHMP5 VPS37A TSG101 PDCD6 MVB12A UBAP1 CHMP1A MVB12B VPS37B VPS37C VPS28 CHMP4A CHMP2B CHMP4B CHMP1B CHMP3 IST1 PDCD6IP	vesicle organization
REAC:R-HSA-162599	3.54576689528e-21	0.5	CHMP2A CHMP5 VPS37A TSG101 MVB12A UBAP1 MVB12B VPS37B VPS28 CHMP4A CHMP2B CHMP4B CHMP3 VPS37C PDCD6IP	Late Phase of HIV Life Cycle
REAC:R-HSA-9610379	7.44967850022e-21	0.466666666667	CHMP2A VPS37A TSG101 MVB12A UBAP1 MVB12B VPS37B VPS28 CHMP4A CHMP2B CHMP4B CHMP3 VPS37C CHMP1A	HCMV Late Events
REAC:R-HSA-162587	1.41829005529e-20	0.5	CHMP2A CHMP5 VPS37A TSG101 MVB12A UBAP1 MVB12B VPS37B VPS28 CHMP4A CHMP2B CHMP4B CHMP3 VPS37C PDCD6IP	HIV Life Cycle
GO:0061952	9.77535301332e-20	0.333333333333	CHMP2A CHMP1A CHMP5 MITD1 CHMP2B CHMP1B CHMP4B CHMP3 PDCD6IP CHMP4A	midbody abscission
GO:0019058	1.36051887297e-19	0.566666666667	CHMP2A CHMP5 VPS37A TSG101 MVB12A CHMP1A MVB12B VPS37B VPS37C VPS28 CHMP4A CHMP2B CHMP4B CHMP1B CHMP3 IST1 PDCD6IP	viral life cycle
GO:0035891	2.15424607614e-19	0.366666666667	CHMP2A CHMP1A CHMP5 VPS37B TSG101 CHMP2B CHMP1B CHMP4B CHMP3 IST1 CHMP4A	exit from host cell
GO:0019076	2.15424607614e-19	0.366666666667	CHMP2A CHMP1A CHMP5 VPS37B TSG101 CHMP2B CHMP1B CHMP4B CHMP3 IST1 CHMP4A	viral release from host cell
CORUM:1186	6.05441064213e-19	0.266666666667	CHMP2A CHMP1A CHMP5 CHMP2B CHMP1B CHMP4B CHMP3 CHMP4A	ESCRT-III complex
REAC:R-HSA-9609646	1.50370661753e-18	0.466666666667	CHMP2A VPS37A TSG101 MVB12A UBAP1 MVB12B VPS37B VPS28 CHMP4A CHMP2B CHMP4B CHMP3 VPS37C CHMP1A	HCMV Infection
GO:0016197	1.71441927638e-18	0.566666666667	CHMP2A CHMP5 VPS37A TSG101 MVB12A UBAP1 MVB12B PTPN23 VPS28 CHMP4A CHMP2B VPS37B CHMP4B CHMP1B CHMP3 VPS37C CHMP1A	endosomal transport
REAC:R-HSA-162906	1.32305481013e-17	0.5	CHMP2A CHMP5 VPS37A TSG101 MVB12A UBAP1 MVB12B VPS37B VPS28 CHMP4A CHMP2B CHMP4B CHMP3 VPS37C PDCD6IP	HIV Infection
GO:0032506	1.39592362203e-17	0.366666666667	CHMP2A SPAST CHMP1A CHMP5 MITD1 CHMP2B CHMP1B CHMP4B CHMP3 PDCD6IP CHMP4A	cytokinetic process
GO:0010256	1.4971816631e-17	0.633333333333	CHMP2A SPAST CHMP5 VPS37A TSG101 MVB12A UBAP1 CHMP1A MVB12B VPS37B VPS37C VPS28 CHMP4A CHMP2B CHMP4B CHMP1B CHMP3 IST1 PDCD6IP	endomembrane system organization
GO:0032510	1.70144877329e-17	0.3	CHMP2A CHMP1A CHMP5 MVB12A CHMP2B CHMP1B CHMP4B CHMP3 CHMP4A	endosome to lysosome transport via multivesicular body sorting pathway
GO:1902410	2.37035057301e-17	0.333333333333	CHMP2A CHMP1A CHMP5 MITD1 CHMP2B CHMP1B CHMP4B CHMP3 PDCD6IP CHMP4A	mitotic cytokinetic process
GO:0061024	4.19158780935e-17	0.666666666667	CHMP2A SPAST CHMP5 VPS37A TSG101 PDCD6 MVB12A MITD1 CHMP1A UBAP1 MVB12B VPS37B VPS28 CHMP4A CHMP2B CHMP4B CHMP1B CHMP3 VPS37C PDCD6IP	membrane organization
GO:0043328	9.69741212683e-17	0.3	VPS37A MVB12A TSG101 UBAP1 PTPN23 MVB12B VPS28 VPS37C VPS37B	protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
GO:0016032	1.07358614908e-16	0.566666666667	CHMP2A CHMP5 VPS37A TSG101 MVB12A CHMP1A MVB12B VPS37B VPS37C VPS28 CHMP4A CHMP2B CHMP4B CHMP1B CHMP3 IST1 PDCD6IP	viral process
REAC:R-HSA-174495	1.15093773956e-16	0.266666666667	VPS37A MVB12A TSG101 UBAP1 MVB12B VPS28 VPS37C VPS37B	Synthesis And Processing Of GAG, GAGPOL Polyproteins
REAC:R-HSA-174490	1.15093773956e-16	0.266666666667	VPS37A MVB12A TSG101 UBAP1 MVB12B VPS28 VPS37C VPS37B	Membrane binding and targetting of GAG proteins
REAC:R-HSA-9612973	1.26390459422e-16	0.433333333333	CHMP2A VPS37A TSG101 MVB12A UBAP1 MVB12B VPS37B VPS28 CHMP4A CHMP4B CHMP3 VPS37C CHMP2B	Autophagy
GO:0061763	2.54890688034e-16	0.266666666667	CHMP2A CHMP1A CHMP5 CHMP2B CHMP1B CHMP4B CHMP3 CHMP4A	multivesicular body-lysosome fusion
GO:0000813	2.54890688034e-16	0.266666666667	VPS37A MVB12A TSG101 UBAP1 MVB12B VPS28 VPS37C VPS37B	ESCRT I complex
GO:0051469	2.54890688034e-16	0.266666666667	CHMP2A CHMP1A CHMP5 CHMP2B CHMP1B CHMP4B CHMP3 CHMP4A	vesicle fusion with vacuole
GO:1904930	2.54890688034e-16	0.266666666667	CHMP2A CHMP1A CHMP5 CHMP2B CHMP1B CHMP4B CHMP3 CHMP4A	amphisome membrane
REAC:R-HSA-175474	4.91938800453e-16	0.266666666667	VPS37A MVB12A TSG101 UBAP1 MVB12B VPS28 VPS37C VPS37B	Assembly Of The HIV Virion
GO:0097576	9.33347854769e-16	0.266666666667	CHMP2A CHMP1A CHMP5 CHMP2B CHMP1B CHMP4B CHMP3 CHMP4A	vacuole fusion
GO:0044753	9.33347854769e-16	0.266666666667	CHMP2A CHMP1A CHMP5 CHMP2B CHMP1B CHMP4B CHMP3 CHMP4A	amphisome
GO:0046761	2.79629441836e-15	0.266666666667	CHMP2A CHMP1A CHMP5 CHMP2B CHMP1B CHMP4B CHMP3 CHMP4A	viral budding from plasma membrane
GO:0097212	2.79629441836e-15	0.266666666667	CHMP2A CHMP1A CHMP5 CHMP2B CHMP1B CHMP4B CHMP3 CHMP4A	lysosomal membrane organization
GO:0046753	7.26063032364e-15	0.266666666667	CHMP2A CHMP1A CHMP5 CHMP2B CHMP1B CHMP4B CHMP3 CHMP4A	non-lytic viral release
GO:0031468	1.09691213895e-14	0.3	CHMP2A SPAST CHMP1A CHMP5 CHMP2B CHMP1B CHMP4B CHMP3 CHMP4A	nuclear membrane reassembly
GO:0061640	2.67119998634e-14	0.4	CHMP2A SPAST CHMP1A CHMP5 MITD1 CHMP2B CHMP1B CHMP4B IST1 CHMP3 PDCD6IP CHMP4A	cytoskeleton-dependent cytokinesis
GO:0010008	3.08268287158e-14	0.533333333333	CHMP2A CHMP5 VPS37A TSG101 MVB12A UBAP1 MVB12B VPS37B VPS28 CHMP4A CHMP2B CHMP4B CHMP1B CHMP3 VPS37C CHMP1A	endosome membrane
GO:0030496	4.25997822667e-14	0.433333333333	CHMP2A SPAST CHMP1A CHMP5 VPS37B MITD1 CHMP2B CHMP1B CHMP4B IST1 CHMP3 PDCD6IP CHMP4A	midbody
GO:0016236	4.83403298978e-14	0.5	CHMP2A CHMP5 VPS37A TSG101 MVB12A CHMP1A VPS37B VPS28 CHMP4A CHMP2B CHMP4B CHMP1B CHMP3 VPS37C PDCD6IP	macroautophagy
GO:0000815	1.29500980951e-13	0.233333333333	CHMP2A CHMP1A CHMP2B CHMP1B CHMP4B CHMP3 CHMP4A	ESCRT III complex
GO:0005768	1.40425601838e-13	0.633333333333	CHMP2A SPAST CHMP5 VPS37A TSG101 MVB12A UBAP1 CHMP1A MVB12B PTPN23 VPS28 CHMP4A CHMP2B VPS37B CHMP4B CHMP1B CHMP3 VPS37C PDCD6IP	endosome
GO:0000281	1.62488391265e-13	0.366666666667	CHMP2A SPAST CHMP1A CHMP5 MITD1 CHMP2B CHMP1B CHMP4B CHMP3 PDCD6IP CHMP4A	mitotic cytokinesis
GO:1901673	2.45212868282e-13	0.266666666667	CHMP2A CHMP1A CHMP5 CHMP2B CHMP1B CHMP4B CHMP3 CHMP4A	regulation of mitotic spindle assembly
GO:1902774	2.45212868282e-13	0.266666666667	CHMP2A CHMP1A CHMP5 CHMP2B CHMP1B CHMP4B CHMP3 CHMP4A	late endosome to lysosome transport
GO:0070925	2.61710081082e-13	0.633333333333	CHMP2A CHMP5 VPS37A TSG101 MVB12A UBAP1 CHMP1A MVB12B PTPN23 VPS37C VPS28 CHMP4A CHMP2B VPS37B CHMP4B CHMP1B CHMP3 IST1 PDCD6IP	organelle assembly
GO:0051603	2.62830003948e-13	0.6	CHMP2A CHMP5 VPS37A TSG101 MVB12A UBAP1 CHMP1A MVB12B PTPN23 VPS28 CHMP4A CHMP2B VPS37B CHMP4B CHMP1B CHMP3 VPS37C PDCD6IP	proteolysis involved in protein catabolic process
GO:0006511	2.69559995351e-13	0.566666666667	CHMP2A CHMP5 VPS37A TSG101 MVB12A UBAP1 MVB12B PTPN23 VPS28 CHMP4A CHMP2B VPS37B CHMP4B CHMP1B CHMP3 VPS37C CHMP1A	ubiquitin-dependent protein catabolic process
GO:0006508	3.37032029256e-13	0.7	CHMP2A CHMP4B VPS37A TSG101 PDCD6 MVB12A UBAP1 CHMP1A MVB12B CHMP5 PTPN23 VPS37C VPS28 CHMP4A CHMP2B VPS37B CAPN7 CHMP1B CHMP3 IST1 PDCD6IP	proteolysis
GO:0019941	3.53947638718e-13	0.566666666667	CHMP2A CHMP5 VPS37A TSG101 MVB12A UBAP1 MVB12B PTPN23 VPS28 CHMP4A CHMP2B VPS37B CHMP4B CHMP1B CHMP3 VPS37C CHMP1A	modification-dependent protein catabolic process
GO:0008333	4.13500267376e-13	0.333333333333	CHMP2A CHMP1A MVB12A CHMP5 TSG101 CHMP2B CHMP1B CHMP4B CHMP3 CHMP4A	endosome to lysosome transport
GO:0005828	4.2298220599e-13	0.266666666667	CHMP2A CHMP1A CHMP5 CHMP2B CHMP1B CHMP4B CHMP3 CHMP4A	kinetochore microtubule
GO:0043632	5.10960821348e-13	0.566666666667	CHMP2A CHMP5 VPS37A TSG101 MVB12A UBAP1 MVB12B PTPN23 VPS28 CHMP4A CHMP2B VPS37B CHMP4B CHMP1B CHMP3 VPS37C CHMP1A	modification-dependent macromolecule catabolic process
GO:0032585	7.04026077755e-13	0.266666666667	CHMP2A CHMP1A CHMP5 CHMP2B CHMP1B CHMP4B CHMP3 CHMP4A	multivesicular body membrane
GO:0071763	2.24688966982e-12	0.3	CHMP2A SPAST CHMP1A CHMP5 CHMP2B CHMP1B CHMP4B CHMP3 CHMP4A	nuclear membrane organization
GO:0001778	4.08844823247e-12	0.266666666667	CHMP2A CHMP1A CHMP5 CHMP2B CHMP1B CHMP4B CHMP3 CHMP4A	plasma membrane repair
GO:0090169	6.00436878524e-12	0.266666666667	CHMP2A CHMP1A CHMP5 CHMP2B CHMP1B CHMP4B CHMP3 CHMP4A	regulation of spindle assembly
GO:0000910	6.10584393974e-12	0.4	CHMP2A SPAST CHMP1A CHMP5 MITD1 CHMP2B CHMP1B CHMP4B IST1 CHMP3 PDCD6IP CHMP4A	cytokinesis
GO:0005771	8.98279918496e-12	0.3	CHMP2A CHMP1A CHMP5 TSG101 CHMP2B CHMP1B CHMP4B CHMP3 CHMP4A	multivesicular body
GO:0051701	9.58027118063e-12	0.366666666667	CHMP2A CHMP1A CHMP5 VPS37B TSG101 CHMP2B CHMP1B CHMP4B CHMP3 IST1 CHMP4A	biological process involved in interaction with host
GO:0006998	1.36387897835e-11	0.3	CHMP2A SPAST CHMP1A CHMP5 CHMP2B CHMP1B CHMP4B CHMP3 CHMP4A	nuclear envelope organization
GO:0071709	1.66858566922e-11	0.3	CHMP2A SPAST CHMP1A CHMP5 CHMP2B CHMP1B CHMP4B CHMP3 CHMP4A	membrane assembly
GO:0097352	1.66858566922e-11	0.3	CHMP2A CHMP1A CHMP5 TSG101 CHMP2B CHMP1B CHMP4B CHMP3 CHMP4A	autophagosome maturation
GO:0030163	1.71246165616e-11	0.6	CHMP2A CHMP5 VPS37A TSG101 MVB12A UBAP1 CHMP1A MVB12B PTPN23 VPS28 CHMP4A CHMP2B VPS37B CHMP4B CHMP1B CHMP3 VPS37C PDCD6IP	protein catabolic process
REAC:R-HSA-9824446	1.82987413687e-11	0.533333333333	CHMP2A CHMP5 VPS37A TSG101 MVB12A UBAP1 CHMP1A MVB12B VPS37B VPS28 CHMP4A CHMP2B CHMP4B CHMP3 VPS37C PDCD6IP	Viral Infection Pathways
GO:0016192	2.02417394096e-11	0.666666666667	CHMP2A SPAST CHMP5 VPS37A TSG101 PDCD6 MVB12A UBAP1 CHMP1A MVB12B PTPN23 VPS28 CHMP4A CHMP2B VPS37B CHMP4B CHMP1B CHMP3 VPS37C PDCD6IP	vesicle-mediated transport
GO:0044091	2.97645978807e-11	0.3	CHMP2A SPAST CHMP1A CHMP5 CHMP2B CHMP1B CHMP4B CHMP3 CHMP4A	membrane biogenesis
GO:0072666	3.58063198688e-11	0.3	VPS37A MVB12A TSG101 UBAP1 PTPN23 MVB12B VPS28 VPS37C VPS37B	establishment of protein localization to vacuole
REAC:R-HSA-9668328	3.71548073675e-11	0.233333333333	CHMP2A SPAST IST1 CHMP2B CHMP4B CHMP3 CHMP4A	Sealing of the nuclear envelope (NE) by ESCRT-III
GO:0000421	7.62555413294e-11	0.266666666667	CHMP2A CHMP1A CHMP5 CHMP2B CHMP1B CHMP4B CHMP3 CHMP4A	autophagosome membrane
GO:0061919	7.7454712882e-11	0.5	CHMP2A CHMP5 VPS37A TSG101 MVB12A CHMP1A VPS37B VPS28 CHMP4A CHMP2B CHMP4B CHMP1B CHMP3 VPS37C PDCD6IP	process utilizing autophagic mechanism
GO:0006914	7.7454712882e-11	0.5	CHMP2A CHMP5 VPS37A TSG101 MVB12A CHMP1A VPS37B VPS28 CHMP4A CHMP2B CHMP4B CHMP1B CHMP3 VPS37C PDCD6IP	autophagy
GO:0045184	8.63996240471e-11	0.633333333333	CHMP2A MVB12A VPS37A TSG101 PDCD6 CD2AP UBAP1 MVB12B PTPN23 VPS37C VPS28 CHMP4A CHMP2B VPS37B CHMP4B CHMP1B CHMP3 IST1 CHMP1A	establishment of protein localization
GO:0060236	1.28918812992e-10	0.266666666667	CHMP2A CHMP1A CHMP5 CHMP2B CHMP1B CHMP4B CHMP3 CHMP4A	regulation of mitotic spindle organization
GO:0031410	1.67443571426e-10	0.733333333333	VPS37A PDCD6 CHMP4A VPS9D1 VPS37B PDCD6IP CHMP2A CHMP1A CHMP5 TSG101 CHMP2B CHMP4B IST1 PTPN23 VPS28 SPAST CHMP3 UBAP1 MVB12B MVB12A CHMP1B VPS37C	cytoplasmic vesicle
GO:0097708	1.73975031e-10	0.733333333333	VPS37A PDCD6 CHMP4A VPS9D1 VPS37B PDCD6IP CHMP2A CHMP1A CHMP5 TSG101 CHMP2B CHMP4B IST1 PTPN23 VPS28 SPAST CHMP3 UBAP1 MVB12B MVB12A CHMP1B VPS37C	intracellular vesicle
GO:1904896	1.83662539324e-10	0.2	CHMP2A CHMP1A CHMP5 CHMP2B CHMP1B IST1	ESCRT complex disassembly
GO:1904903	1.83662539324e-10	0.2	CHMP2A CHMP1A CHMP5 CHMP2B CHMP1B IST1	ESCRT III complex disassembly
GO:0090224	2.10911096635e-10	0.266666666667	CHMP2A CHMP1A CHMP5 CHMP2B CHMP1B CHMP4B CHMP3 CHMP4A	regulation of spindle organization
GO:0010824	2.66795930329e-10	0.266666666667	CHMP2A CHMP1A CHMP5 CHMP2B CHMP1B CHMP4B CHMP3 PDCD6IP	regulation of centrosome duplication
GO:0030659	3.24989075022e-10	0.566666666667	CHMP2A CHMP5 VPS37A TSG101 PDCD6 MVB12A UBAP1 MVB12B VPS37B VPS28 CHMP4A CHMP2B CHMP4B CHMP1B CHMP3 VPS37C CHMP1A	cytoplasmic vesicle membrane
GO:0007041	3.47494021418e-10	0.333333333333	CHMP2A CHMP1A MVB12A CHMP5 TSG101 CHMP2B CHMP1B CHMP4B CHMP3 CHMP4A	lysosomal transport
GO:0046907	3.48275195204e-10	0.633333333333	CHMP2A SPAST CHMP5 VPS37A TSG101 PDCD6 MVB12A UBAP1 MVB12B PTPN23 VPS28 CHMP4A CHMP2B VPS37B CHMP4B CHMP1B CHMP3 VPS37C CHMP1A	intracellular transport
GO:0012506	4.22246415003e-10	0.566666666667	CHMP2A CHMP5 VPS37A TSG101 PDCD6 MVB12A UBAP1 MVB12B VPS37B VPS28 CHMP4A CHMP2B CHMP4B CHMP1B CHMP3 VPS37C CHMP1A	vesicle membrane
REAC:R-HSA-5663205	4.39646257034e-10	0.533333333333	CHMP2A CHMP5 VPS37A TSG101 MVB12A UBAP1 CHMP1A MVB12B VPS37B VPS28 CHMP4A CHMP2B CHMP4B CHMP3 VPS37C PDCD6IP	Infectious disease
REAC:R-HSA-199991	4.8063179451e-10	0.466666666667	CHMP2A VPS37A TSG101 MVB12A UBAP1 MVB12B VPS37B VPS28 CHMP4A CHMP5 CHMP4B CHMP3 VPS37C CHMP2B	Membrane Trafficking
GO:0046605	6.40474542033e-10	0.266666666667	CHMP2A CHMP1A CHMP5 CHMP2B CHMP1B CHMP4B CHMP3 PDCD6IP	regulation of centrosome cycle
GO:0051301	7.94945428832e-10	0.4	CHMP2A SPAST CHMP1A CHMP5 MITD1 CHMP2B CHMP1B CHMP4B IST1 CHMP3 PDCD6IP CHMP4A	cell division
GO:0072665	9.86206224728e-10	0.3	VPS37A MVB12A TSG101 UBAP1 PTPN23 MVB12B VPS28 VPS37C VPS37B	protein localization to vacuole
REAC:R-HSA-5653656	1.0027780253e-09	0.466666666667	CHMP2A VPS37A TSG101 MVB12A UBAP1 MVB12B VPS37B VPS28 CHMP4A CHMP5 CHMP4B CHMP3 VPS37C CHMP2B	Vesicle-mediated transport
GO:0051649	1.83105727742e-09	0.666666666667	CHMP2A SPAST CHMP5 VPS37A TSG101 PDCD6 MVB12A UBAP1 CHMP1A MVB12B PTPN23 VPS28 CHMP4A CHMP2B VPS37B CHMP4B CHMP1B CHMP3 VPS37C PDCD6IP	establishment of localization in cell
REAC:R-HSA-9679504	3.9984676129e-09	0.166666666667	CHMP2A CHMP2B CHMP4A CHMP4B CHMP3	Translation of Replicase and Assembly of the Replication Transcription Complex
GO:0009057	4.20465438382e-09	0.6	CHMP2A CHMP5 VPS37A TSG101 MVB12A UBAP1 CHMP1A MVB12B PTPN23 VPS28 CHMP4A CHMP2B VPS37B CHMP4B CHMP1B CHMP3 VPS37C PDCD6IP	macromolecule catabolic process
GO:0044403	4.40562482703e-09	0.366666666667	CHMP2A CHMP1A CHMP5 VPS37B TSG101 CHMP2B CHMP1B CHMP4B CHMP3 IST1 CHMP4A	biological process involved in symbiotic interaction
GO:1901565	4.79414660809e-09	0.6	CHMP2A CHMP5 VPS37A TSG101 MVB12A UBAP1 CHMP1A MVB12B PTPN23 VPS28 CHMP4A CHMP2B VPS37B CHMP4B CHMP1B CHMP3 VPS37C PDCD6IP	organonitrogen compound catabolic process
REAC:R-HSA-9694676	6.84474057061e-09	0.166666666667	CHMP2A CHMP2B CHMP4A CHMP4B CHMP3	Translation of Replicase and Assembly of the Replication Transcription Complex
GO:0007080	8.78787206127e-09	0.266666666667	CHMP2A CHMP1A CHMP5 CHMP2B CHMP1B CHMP4B CHMP3 CHMP4A	mitotic metaphase chromosome alignment
GO:0015031	1.01497206193e-08	0.533333333333	CHMP2A MVB12A VPS37A TSG101 PDCD6 CD2AP UBAP1 MVB12B PTPN23 VPS28 CHMP2B VPS37B CHMP1B CHMP3 VPS37C CHMP1A	protein transport
GO:0031982	1.19215261146e-08	0.833333333333	VPS37A PDCD6 CHMP4A VPS9D1 VPS37B PDCD6IP CHMP2A CHMP1A MITD1 CHMP5 TSG101 CHMP2B CHMP4B IST1 PTPN23 VPS28 SPAST CAPN7 CHMP3 UBAP1 MVB12B MVB12A CD2AP CHMP1B VPS37C	vesicle
KEGG:04217	1.51662718932e-08	0.266666666667	CHMP2A CHMP1A CHMP5 CHMP2B CHMP1B CHMP4B CHMP3 CHMP4A	Necroptosis
GO:0090307	1.55773255273e-08	0.266666666667	CHMP2A CHMP1A CHMP5 CHMP2B CHMP1B CHMP4B CHMP3 CHMP4A	mitotic spindle assembly
REAC:R-HSA-2995410	1.9643980532e-08	0.233333333333	CHMP2A SPAST IST1 CHMP2B CHMP4B CHMP3 CHMP4A	Nuclear Envelope (NE) Reassembly
GO:0070062	2.36819494864e-08	0.7	CHMP2A SPAST MVB12A CHMP1A TSG101 PDCD6 CD2AP MITD1 MVB12B CHMP5 PTPN23 VPS37C VPS28 PDCD6IP CHMP4B VPS37B CAPN7 CHMP1B CHMP3 IST1 CHMP2B	extracellular exosome
GO:0051298	2.65562158158e-08	0.266666666667	CHMP2A CHMP1A CHMP5 CHMP2B CHMP1B CHMP4B CHMP3 PDCD6IP	centrosome duplication
GO:0006997	2.70065758694e-08	0.3	CHMP2A SPAST CHMP1A CHMP5 CHMP2B CHMP1B CHMP4B CHMP3 CHMP4A	nucleus organization
GO:1903561	2.84605915764e-08	0.7	CHMP2A SPAST MVB12A CHMP1A TSG101 PDCD6 CD2AP MITD1 MVB12B CHMP5 PTPN23 VPS37C VPS28 PDCD6IP CHMP4B VPS37B CAPN7 CHMP1B CHMP3 IST1 CHMP2B	extracellular vesicle
GO:0043230	2.87683510317e-08	0.7	CHMP2A SPAST MVB12A CHMP1A TSG101 PDCD6 CD2AP MITD1 MVB12B CHMP5 PTPN23 VPS37C VPS28 PDCD6IP CHMP4B VPS37B CAPN7 CHMP1B CHMP3 IST1 CHMP2B	extracellular organelle
GO:0065010	2.87683510317e-08	0.7	CHMP2A SPAST MVB12A CHMP1A TSG101 PDCD6 CD2AP MITD1 MVB12B CHMP5 PTPN23 VPS37C VPS28 PDCD6IP CHMP4B VPS37B CAPN7 CHMP1B CHMP3 IST1 CHMP2B	extracellular membrane-bounded organelle
GO:1902115	2.9740392759e-08	0.333333333333	CHMP2A CHMP1A CHMP5 TSG101 CHMP4A CHMP2B CHMP4B CHMP1B CHMP3 PDCD6IP	regulation of organelle assembly
GO:0007052	4.46183902555e-08	0.3	CHMP2A SPAST CHMP1A CHMP5 CHMP2B CHMP1B CHMP4B CHMP3 CHMP4A	mitotic spindle organization
GO:0022607	6.68471561065e-08	0.733333333333	VPS37A PDCD6 CHMP4A VPS37B PDCD6IP CHMP2A CHMP1A CD2AP TSG101 CHMP2B CHMP4B IST1 PTPN23 UBAP1 SPAST CHMP3 VPS28 MVB12B MVB12A CHMP5 CHMP1B VPS37C	cellular component assembly
GO:0005876	7.83438937183e-08	0.266666666667	CHMP2A CHMP1A CHMP5 CHMP2B CHMP1B CHMP4B CHMP3 CHMP4A	spindle microtubule
GO:0005776	9.77527975935e-08	0.266666666667	CHMP2A CHMP1A CHMP5 CHMP2B CHMP1B CHMP4B CHMP3 CHMP4A	autophagosome
WP:WP4932	1.01663613195e-07	0.233333333333	VPS37A VPS28 MVB12A TSG101 VPS37C VPS9D1 VPS37B	7q11 23 copy number variation syndrome
GO:0031902	1.34705489315e-07	0.266666666667	CHMP2A CHMP1A CHMP5 CHMP2B CHMP1B CHMP4B CHMP3 CHMP4A	late endosome membrane
GO:0051656	1.51386155261e-07	0.4	CHMP2A SPAST CHMP1A PDCD6 CHMP5 TSG101 CHMP4A CHMP2B CHMP4B CHMP1B CHMP3 PDCD6IP	establishment of organelle localization
GO:0098796	1.77368996328e-07	0.533333333333	CHMP2A VPS37A TSG101 PDCD6 MVB12A UBAP1 MVB12B VPS37B VPS28 CHMP4A CHMP2B CHMP4B CHMP1B CHMP3 VPS37C CHMP1A	membrane protein complex
GO:0032984	1.77900543604e-07	0.333333333333	CHMP2A CHMP1A CHMP5 TSG101 CHMP2B CHMP1B CHMP4B CHMP3 IST1 CHMP4A	protein-containing complex disassembly
GO:0007040	1.83288830494e-07	0.266666666667	CHMP2A CHMP1A CHMP5 CHMP2B CHMP1B CHMP4B CHMP3 CHMP4A	lysosome organization
GO:0080171	1.83288830494e-07	0.266666666667	CHMP2A CHMP1A CHMP5 CHMP2B CHMP1B CHMP4B CHMP3 CHMP4A	lytic vacuole organization
GO:0005643	2.02567181384e-07	0.266666666667	CHMP2A CHMP1A CHMP5 CHMP2B CHMP1B CHMP4B CHMP3 CHMP4A	nuclear pore
GO:0005770	2.2877463354e-07	0.333333333333	CHMP2A CHMP1A CHMP5 MVB12B TSG101 CHMP4A CHMP1B CHMP4B CHMP3 CHMP2B	late endosome
REAC:R-HSA-5620971	2.86276360145e-07	0.166666666667	CHMP2A CHMP2B CHMP4A CHMP4B CHMP3	Pyroptosis
GO:1902850	3.1597126853e-07	0.3	CHMP2A SPAST CHMP1A CHMP5 CHMP2B CHMP1B CHMP4B CHMP3 CHMP4A	microtubule cytoskeleton organization involved in mitosis
REAC:R-HSA-5218859	3.20923265415e-07	0.2	CHMP2A CHMP2B CHMP4B CHMP3 PDCD6IP CHMP4A	Regulated Necrosis
GO:0051641	3.35862096299e-07	0.733333333333	VPS37A PDCD6 CHMP4A VPS37B PDCD6IP CHMP2A CHMP1A CD2AP TSG101 CHMP2B CHMP4B IST1 PTPN23 UBAP1 SPAST CHMP3 VPS28 MVB12B MVB12A CHMP5 CHMP1B VPS37C	cellular localization
GO:0006906	3.94365016622e-07	0.266666666667	CHMP2A CHMP1A CHMP5 CHMP2B CHMP1B CHMP4B CHMP3 CHMP4A	vesicle fusion
GO:0051310	4.31795120439e-07	0.266666666667	CHMP2A CHMP1A CHMP5 CHMP2B CHMP1B CHMP4B CHMP3 CHMP4A	metaphase chromosome alignment
GO:0044085	4.45813590808e-07	0.733333333333	VPS37A PDCD6 CHMP4A VPS37B PDCD6IP CHMP2A CHMP1A CD2AP TSG101 CHMP2B CHMP4B IST1 PTPN23 UBAP1 SPAST CHMP3 VPS28 MVB12B MVB12A CHMP5 CHMP1B VPS37C	cellular component biogenesis
GO:0090174	4.72282978193e-07	0.266666666667	CHMP2A CHMP1A CHMP5 CHMP2B CHMP1B CHMP4B CHMP3 CHMP4A	organelle membrane fusion
GO:0051303	5.63284348123e-07	0.266666666667	CHMP2A CHMP1A CHMP5 CHMP2B CHMP1B CHMP4B CHMP3 CHMP4A	establishment of chromosome localization
GO:0008104	7.43409061783e-07	0.633333333333	CHMP2A MVB12A VPS37A TSG101 PDCD6 CD2AP UBAP1 MVB12B PTPN23 VPS37C VPS28 CHMP4A CHMP2B VPS37B CHMP4B CHMP1B CHMP3 IST1 CHMP1A	protein localization
GO:0070727	7.76077831219e-07	0.633333333333	CHMP2A MVB12A VPS37A TSG101 PDCD6 CD2AP UBAP1 MVB12B PTPN23 VPS37C VPS28 CHMP4A CHMP2B VPS37B CHMP4B CHMP1B CHMP3 IST1 CHMP1A	cellular macromolecule localization
GO:0050000	8.60516399267e-07	0.266666666667	CHMP2A CHMP1A CHMP5 CHMP2B CHMP1B CHMP4B CHMP3 CHMP4A	chromosome localization
CORUM:1192	9.2695336525e-07	0.1	VPS28 VPS37C TSG101	ESCRT-I complex
CORUM:1863	9.2695336525e-07	0.1	VPS28 VPS37B TSG101	TSG101-VPS37B-VPS28 complex
GO:0051225	1.09781568071e-06	0.266666666667	CHMP2A CHMP1A CHMP5 CHMP2B CHMP1B CHMP4B CHMP3 CHMP4A	spindle assembly
GO:0007051	1.18423048385e-06	0.3	CHMP2A SPAST CHMP1A CHMP5 CHMP2B CHMP1B CHMP4B CHMP3 CHMP4A	spindle organization
GO:0005615	1.28660377914e-06	0.733333333333	PDCD6 PSPN PDCD6IP CHMP2A CHMP1A MITD1 CD2AP VPS37B TSG101 CHMP2B CHMP4B IST1 PTPN23 VPS28 SPAST CAPN7 CHMP3 MVB12B MVB12A CHMP5 CHMP1B VPS37C	extracellular space
GO:0007009	1.39017619813e-06	0.266666666667	CHMP2A CHMP1A CHMP5 CHMP2B CHMP1B CHMP4B CHMP3 CHMP4A	plasma membrane organization
REAC:R-HSA-1643685	1.47858131344e-06	0.533333333333	CHMP2A CHMP5 VPS37A TSG101 MVB12A UBAP1 CHMP1A MVB12B VPS37B VPS28 CHMP4A CHMP2B CHMP4B CHMP3 VPS37C PDCD6IP	Disease
GO:0072594	1.63946719225e-06	0.366666666667	VPS37A MVB12A TSG101 UBAP1 MVB12B PTPN23 VPS28 CHMP4A CHMP4B VPS37B VPS37C	establishment of protein localization to organelle
GO:0071705	1.81516627401e-06	0.533333333333	CHMP2A MVB12A VPS37A TSG101 PDCD6 CD2AP UBAP1 MVB12B PTPN23 VPS28 CHMP2B VPS37B CHMP1B CHMP3 VPS37C CHMP1A	nitrogen compound transport
GO:1901575	1.91741845391e-06	0.6	CHMP2A CHMP5 VPS37A TSG101 MVB12A UBAP1 CHMP1A MVB12B PTPN23 VPS28 CHMP4A CHMP2B VPS37B CHMP4B CHMP1B CHMP3 VPS37C PDCD6IP	organic substance catabolic process
REAC:R-HSA-9772572	1.990568722e-06	0.166666666667	CHMP2A CHMP2B CHMP4A CHMP4B CHMP3	Early SARS-CoV-2 Infection Events
GO:0051640	2.65376897518e-06	0.4	CHMP2A SPAST CHMP1A PDCD6 CHMP5 TSG101 CHMP4A CHMP2B CHMP4B CHMP1B CHMP3 PDCD6IP	organelle localization
GO:0007098	3.58407163603e-06	0.266666666667	CHMP2A CHMP1A CHMP5 CHMP2B CHMP1B CHMP4B CHMP3 PDCD6IP	centrosome cycle
GO:0048284	4.69231235926e-06	0.266666666667	CHMP2A CHMP1A CHMP5 CHMP2B CHMP1B CHMP4B CHMP3 CHMP4A	organelle fusion
GO:0006996	6.25305352607e-06	0.733333333333	VPS37A PDCD6 CHMP4A VPS37B PDCD6IP CHMP2A CHMP1A CD2AP TSG101 CHMP2B CHMP4B IST1 PTPN23 UBAP1 SPAST CHMP3 VPS28 MVB12B MVB12A CHMP5 CHMP1B VPS37C	organelle organization
GO:0032886	6.54821690175e-06	0.3	CHMP2A CHMP1A CHMP5 CHMP2B CHMP1B CHMP4B CHMP3 PDCD6IP CHMP4A	regulation of microtubule-based process
GO:0061025	7.35811133512e-06	0.266666666667	CHMP2A CHMP1A CHMP5 CHMP2B CHMP1B CHMP4B CHMP3 CHMP4A	membrane fusion
GO:0070507	7.83005675101e-06	0.266666666667	CHMP2A CHMP1A CHMP5 CHMP2B CHMP1B CHMP4B CHMP3 CHMP4A	regulation of microtubule cytoskeleton organization
GO:0005576	9.34785815362e-06	0.733333333333	PDCD6 PSPN PDCD6IP CHMP2A CHMP1A MITD1 CD2AP VPS37B TSG101 CHMP2B CHMP4B IST1 PTPN23 VPS28 SPAST CAPN7 CHMP3 MVB12B MVB12A CHMP5 CHMP1B VPS37C	extracellular region
GO:0031023	9.99123317391e-06	0.266666666667	CHMP2A CHMP1A CHMP5 CHMP2B CHMP1B CHMP4B CHMP3 PDCD6IP	microtubule organizing center organization
GO:0015630	1.08374222777e-05	0.5	CHMP2A SPAST CHMP4B VPS37A CD2AP PTPN23 CHMP5 MVB12A CHMP4A CHMP2B CAPN7 CHMP1B CHMP3 IST1 CHMP1A	microtubule cytoskeleton
GO:0022411	1.12908414148e-05	0.366666666667	CHMP2A SPAST CHMP1A CHMP5 TSG101 CHMP2B CHMP1B CHMP4B CHMP3 IST1 CHMP4A	cellular component disassembly
GO:0000776	1.19358559799e-05	0.266666666667	CHMP2A CHMP1A CHMP5 CHMP2B CHMP1B CHMP4B CHMP3 CHMP4A	kinetochore
GO:0098588	1.30261172664e-05	0.566666666667	CHMP2A CHMP5 VPS37A TSG101 PDCD6 MVB12A UBAP1 MVB12B VPS37B VPS28 CHMP4A CHMP2B CHMP4B CHMP1B CHMP3 VPS37C CHMP1A	bounding membrane of organelle
GO:0033036	1.33832165016e-05	0.633333333333	CHMP2A MVB12A VPS37A TSG101 PDCD6 CD2AP UBAP1 MVB12B PTPN23 VPS37C VPS28 CHMP4A CHMP2B VPS37B CHMP4B CHMP1B CHMP3 IST1 CHMP1A	macromolecule localization
GO:0000779	1.50353495959e-05	0.266666666667	CHMP2A CHMP1A CHMP5 CHMP2B CHMP1B CHMP4B CHMP3 CHMP4A	condensed chromosome, centromeric region
GO:0140014	2.32616421464e-05	0.3	CHMP2A SPAST CHMP1A CHMP5 CHMP2B CHMP1B CHMP4B CHMP3 CHMP4A	mitotic nuclear division
GO:0071702	3.71852357948e-05	0.533333333333	CHMP2A MVB12A VPS37A TSG101 PDCD6 CD2AP UBAP1 MVB12B PTPN23 VPS28 CHMP2B VPS37B CHMP1B CHMP3 VPS37C CHMP1A	organic substance transport
GO:0000070	4.33851086628e-05	0.266666666667	CHMP2A CHMP1A CHMP5 CHMP2B CHMP1B CHMP4B CHMP3 CHMP4A	mitotic sister chromatid segregation
GO:0051234	4.49872633192e-05	0.733333333333	VPS37A PDCD6 CHMP4A VPS37B PDCD6IP CHMP2A CHMP1A CD2AP TSG101 CHMP2B CHMP4B IST1 PTPN23 UBAP1 SPAST CHMP3 VPS28 MVB12B MVB12A CHMP5 CHMP1B VPS37C	establishment of localization
GO:0009056	7.53329089777e-05	0.6	CHMP2A CHMP5 VPS37A TSG101 MVB12A UBAP1 CHMP1A MVB12B PTPN23 VPS28 CHMP4A CHMP2B VPS37B CHMP4B CHMP1B CHMP3 VPS37C PDCD6IP	catabolic process
GO:0006810	7.63357131919e-05	0.7	CHMP2A SPAST MVB12A VPS37A TSG101 PDCD6 CD2AP UBAP1 CHMP1A MVB12B CHMP5 PTPN23 VPS28 CHMP4A CHMP2B VPS37B CHMP4B CHMP1B CHMP3 VPS37C PDCD6IP	transport
REAC:R-HSA-68882	9.00309096571e-05	0.233333333333	CHMP2A SPAST IST1 CHMP2B CHMP4B CHMP3 CHMP4A	Mitotic Anaphase
GO:0044248	9.22261720266e-05	0.5	CHMP2A CHMP5 VPS37A TSG101 MVB12A CHMP1A VPS37B VPS28 CHMP4A CHMP2B CHMP4B CHMP1B CHMP3 VPS37C PDCD6IP	cellular catabolic process
REAC:R-HSA-2555396	9.28060373226e-05	0.233333333333	CHMP2A SPAST IST1 CHMP2B CHMP4B CHMP3 CHMP4A	Mitotic Metaphase and Anaphase
GO:0007033	0.000109910810406	0.266666666667	CHMP2A CHMP1A CHMP5 CHMP2B CHMP1B CHMP4B CHMP3 CHMP4A	vacuole organization
GO:0000775	0.00020613195344	0.266666666667	CHMP2A CHMP1A CHMP5 CHMP2B CHMP1B CHMP4B CHMP3 CHMP4A	chromosome, centromeric region
GO:0000819	0.000241692308489	0.266666666667	CHMP2A CHMP1A CHMP5 CHMP2B CHMP1B CHMP4B CHMP3 CHMP4A	sister chromatid segregation
GO:0000793	0.000282448549911	0.266666666667	CHMP2A CHMP1A CHMP5 CHMP2B CHMP1B CHMP4B CHMP3 CHMP4A	condensed chromosome
GO:0005819	0.000298026114564	0.3	CHMP2A SPAST CHMP1A CHMP5 CHMP2B CHMP1B CHMP4B CHMP3 CHMP4A	spindle
GO:0005856	0.000320280004711	0.533333333333	CHMP2A SPAST CHMP4B VPS37A CD2AP CHMP1A PTPN23 CHMP5 MVB12A CHMP4A CHMP2B CAPN7 CHMP1B CHMP3 IST1 PDCD6IP	cytoskeleton
KEGG:03250	0.000335613195892	0.133333333333	TSG101 CHMP4B CHMP4A PDCD6IP	Viral life cycle - HIV-1
GO:0090541	0.00039024736677	0.1	CAPN7 IST1 CHMP1B	MIT domain binding
GO:0000280	0.000430274290416	0.3	CHMP2A SPAST CHMP1A CHMP5 CHMP2B CHMP1B CHMP4B CHMP3 CHMP4A	nuclear division
GO:1903047	0.000660075478078	0.366666666667	CHMP2A SPAST CHMP1A CHMP5 MITD1 CHMP2B CHMP1B CHMP4B CHMP3 PDCD6IP CHMP4A	mitotic cell cycle process
REAC:R-HSA-5357801	0.000784266053023	0.2	CHMP2A CHMP2B CHMP4B CHMP3 PDCD6IP CHMP4A	Programmed Cell Death
GO:0051179	0.000947148409732	0.733333333333	VPS37A PDCD6 CHMP4A VPS37B PDCD6IP CHMP2A CHMP1A CD2AP TSG101 CHMP2B CHMP4B IST1 PTPN23 UBAP1 SPAST CHMP3 VPS28 MVB12B MVB12A CHMP5 CHMP1B VPS37C	localization
GO:0098813	0.00107566510533	0.266666666667	CHMP2A CHMP1A CHMP5 CHMP2B CHMP1B CHMP4B CHMP3 CHMP4A	nuclear chromosome segregation
GO:0005635	0.00109983337275	0.3	CHMP2A SPAST CHMP1A CHMP5 CHMP2B CHMP1B CHMP4B CHMP3 CHMP4A	nuclear envelope
GO:0048285	0.00118375096501	0.3	CHMP2A SPAST CHMP1A CHMP5 CHMP2B CHMP1B CHMP4B CHMP3 CHMP4A	organelle fission
GO:0006886	0.00122113220492	0.333333333333	VPS37A MVB12A PDCD6 TSG101 UBAP1 PTPN23 MVB12B VPS28 VPS37C VPS37B	intracellular protein transport
GO:0000226	0.00142573682116	0.333333333333	CHMP2A SPAST CHMP1A CHMP5 CHMP2B CHMP1B CHMP4B CHMP3 PDCD6IP CHMP4A	microtubule cytoskeleton organization
REAC:R-HSA-1632852	0.00179345909688	0.166666666667	CHMP2A CHMP2B CHMP4A CHMP4B CHMP3	Macroautophagy
REAC:R-HSA-9678108	0.00225209372711	0.166666666667	CHMP2A CHMP2B CHMP4A CHMP4B CHMP3	SARS-CoV-1 Infection
GO:0016043	0.00233347298581	0.8	VPS37A PDCD6 CHMP4A VPS37B PDCD6IP CHMP2A CHMP1A MITD1 CD2AP BAZ2B TSG101 CHMP2B CHMP4B IST1 PTPN23 VPS28 SPAST CHMP3 UBAP1 MVB12B MVB12A CHMP5 CHMP1B VPS37C	cellular component organization
GO:0042060	0.00237635719141	0.266666666667	CHMP2A CHMP1A CHMP5 CHMP2B CHMP1B CHMP4B CHMP3 CHMP4A	wound healing
GO:0012505	0.00255514182675	0.7	CHMP2A SPAST CHMP5 VPS37A TSG101 PDCD6 MVB12A UBAP1 CHMP1A MVB12B PTPN23 VPS37C VPS28 CHMP4A CHMP2B VPS37B CHMP4B CHMP1B CHMP3 IST1 PDCD6IP	endomembrane system
GO:0005874	0.00266507884697	0.266666666667	CHMP2A CHMP1A CHMP5 CHMP2B CHMP1B CHMP4B CHMP3 CHMP4A	microtubule
REAC:R-HSA-68886	0.00353614862687	0.233333333333	CHMP2A SPAST IST1 CHMP2B CHMP4B CHMP3 CHMP4A	M Phase
GO:0010564	0.00420566330675	0.333333333333	CHMP2A SPAST CHMP1A CHMP5 CHMP2B CHMP1B CHMP4B CHMP3 PDCD6IP CHMP4A	regulation of cell cycle process
GO:0019538	0.00463433294104	0.7	CHMP2A CHMP4B VPS37A TSG101 PDCD6 MVB12A UBAP1 CHMP1A MVB12B CHMP5 PTPN23 VPS37C VPS28 CHMP4A CHMP2B VPS37B CAPN7 CHMP1B CHMP3 IST1 PDCD6IP	protein metabolic process
GO:0000278	0.00463707555717	0.366666666667	CHMP2A SPAST CHMP1A CHMP5 MITD1 CHMP2B CHMP1B CHMP4B CHMP3 PDCD6IP CHMP4A	mitotic cell cycle
GO:0048306	0.00498839719865	0.166666666667	PDCD6 TSG101 PDCD6IP VPS37C VPS37B	calcium-dependent protein binding
GO:0099513	0.00503362227211	0.3	CHMP2A CHMP1A CD2AP CHMP2B CHMP5 CHMP4B CHMP1B CHMP3 CHMP4A	polymeric cytoskeletal fiber
GO:0071840	0.00524409089743	0.8	VPS37A PDCD6 CHMP4A VPS37B PDCD6IP CHMP2A CHMP1A MITD1 CD2AP BAZ2B TSG101 CHMP2B CHMP4B IST1 PTPN23 VPS28 SPAST CHMP3 UBAP1 MVB12B MVB12A CHMP5 CHMP1B VPS37C	cellular component organization or biogenesis
GO:0033365	0.00540690970073	0.366666666667	VPS37A MVB12A TSG101 UBAP1 MVB12B PTPN23 VPS28 CHMP4A CHMP4B VPS37B VPS37C	protein localization to organelle
GO:0031090	0.00678738810373	0.6	CHMP2A SPAST CHMP5 VPS37A TSG101 PDCD6 MVB12A UBAP1 MVB12B VPS37B VPS28 CHMP4A CHMP2B CHMP4B CHMP1B CHMP3 VPS37C CHMP1A	organelle membrane
GO:0140694	0.00729863096695	0.266666666667	CHMP2A CHMP1A CHMP5 CHMP2B CHMP1B CHMP4B CHMP3 CHMP4A	non-membrane-bounded organelle assembly
HPA:0550053	0.00755938573517	0.466666666667	CHMP2A SPAST MVB12A IST1 TSG101 CD2AP PTPN23 VPS37B VPS28 UMAD1 CHMP4B CHMP3 VPS37C PDCD6IP	stomach 2; glandular cells[High]
GO:0098687	0.00908845728661	0.266666666667	CHMP2A CHMP1A CHMP5 CHMP2B CHMP1B CHMP4B CHMP3 CHMP4A	chromosomal region
GO:0043933	0.00918199196637	0.5	CHMP2A SPAST CHMP5 CHMP1A PDCD6 CD2AP BAZ2B TSG101 CHMP4A CHMP2B CHMP4B CHMP1B CHMP3 IST1 PDCD6IP	protein-containing complex organization
GO:0009611	0.00930884231118	0.266666666667	CHMP2A CHMP1A CHMP5 CHMP2B CHMP1B CHMP4B CHMP3 CHMP4A	response to wounding
GO:0007059	0.00999780731653	0.266666666667	CHMP2A CHMP1A CHMP5 CHMP2B CHMP1B CHMP4B CHMP3 CHMP4A	chromosome segregation
GO:0005765	0.0107301857328	0.266666666667	CHMP2A CHMP1A CHMP5 CHMP2B CHMP1B CHMP4B CHMP3 CHMP4A	lysosomal membrane
GO:0098852	0.0107301857328	0.266666666667	CHMP2A CHMP1A CHMP5 CHMP2B CHMP1B CHMP4B CHMP3 CHMP4A	lytic vacuole membrane
GO:0022402	0.0108036390913	0.4	CHMP2A SPAST CHMP1A CHMP5 MITD1 CHMP2B CHMP1B CHMP4B IST1 CHMP3 PDCD6IP CHMP4A	cell cycle process
HPA:0480053	0.0134233199456	0.466666666667	CHMP2A SPAST IST1 TSG101 CD2AP PTPN23 VPS37C VPS28 CHMP4A CHMP1B CHMP4B CHMP3 PDCD6IP UMAD1	small intestine; glandular cells[High]
GO:0005774	0.0192599163715	0.266666666667	CHMP2A CHMP1A CHMP5 CHMP2B CHMP1B CHMP4B CHMP3 CHMP4A	vacuolar membrane
HP:0007350	0.0212343530961	0.1	UBAP1 VPS37A SPAST	Hyperreflexia in upper limbs
REAC:R-HSA-69278	0.0252995091444	0.233333333333	CHMP2A SPAST IST1 CHMP2B CHMP4B CHMP3 CHMP4A	Cell Cycle, Mitotic
GO:0044087	0.0279041334122	0.333333333333	CHMP2A CHMP1A CHMP5 TSG101 CHMP4A CHMP2B CHMP4B CHMP1B CHMP3 PDCD6IP	regulation of cellular component biogenesis
GO:1901564	0.0280665151461	0.733333333333	VPS37A PDCD6 CHMP4A VPS9D1 VPS37B CHMP2A CHMP1A CHMP5 TSG101 CHMP2B CHMP4B IST1 PTPN23 VPS28 VPS37C CAPN7 CHMP3 UBAP1 MVB12B MVB12A CHMP1B PDCD6IP	organonitrogen compound metabolic process
HPA:0170052	0.0316848333815	0.633333333333	CHMP2A SPAST MVB12A VPS37A TSG101 CD2AP MITD1 UBAP1 PTPN23 VPS37B VPS37C VPS28 CHMP4A CHMP1B CHMP4B IST1 CHMP3 PDCD6IP UMAD1	endometrium 2; glandular cells[>=Medium]
GO:0051493	0.0330589819967	0.266666666667	CHMP2A CHMP1A CHMP5 CHMP2B CHMP1B CHMP4B CHMP3 CHMP4A	regulation of cytoskeleton organization
GO:0007017	0.0345676965777	0.333333333333	CHMP2A SPAST CHMP1A CHMP5 CHMP2B CHMP1B CHMP4B CHMP3 PDCD6IP CHMP4A	microtubule-based process
GO:0030117	0.0421741709629	0.166666666667	PDCD6 CHMP2A CHMP1B CHMP4A CHMP4B	membrane coat
GO:0048475	0.0421741709629	0.166666666667	PDCD6 CHMP2A CHMP1B CHMP4A CHMP4B	coated membrane
GO:0019904	0.0426739352351	0.266666666667	CHMP2A CHMP1A CD2AP MITD1 CHMP2B CHMP1B CAPN7 IST1	protein domain specific binding
GO:0006612	0.0446509323548	0.166666666667	VPS37B CHMP4B CHMP4A VPS37C VPS37A	protein targeting to membrane

Edges

Protein 1	Protein 2	Score	ProteomeHD	Interface Overlap
MVB12A	VPS28	1.0	0.308	structurally_consistent (dimer)
TSG101	VPS37A	1.0	0.67
TSG101	MVB12A	1.0	0.366
VPS37B	TSG101	1.0	0.252
VPS37B	VPS28	1.0	0.534
VPS28	VPS37A	1.0	0.484
TSG101	VPS28	1.0	0.912
IST1	SPAST	1.0	0.102
CHMP1A	CHMP2B	1.0	0.088
TSG101	UBAP1	1.0	0.07
VPS28	UBAP1	1.0	0.138
CHMP4B	CHMP1B	0.999	0.176
MVB12B	VPS28	0.999	0.094
VPS37A	UBAP1	0.999	0.17
CHMP1A	CHMP4B	0.999	0.124
IST1	CHMP1B	0.999	0.186	structurally_consistent (Q9Y3E7) structurally_consistent (dimer)
TSG101	VPS37C	0.999	0.252
CHMP3	CHMP4B	0.999	0.118
CHMP2B	CHMP4B	0.999	0.144	mutually_exclusive (Q9NZZ3)
VPS28	VPS37C	0.999	0.164	structurally_consistent (Q96EY5) structurally_consistent (dimer)
CHMP5	CHMP4B	0.999	0.14	structurally_consistent (dimer)
CHMP3	CHMP2A	0.998	0.11	structurally_consistent (dimer)
CHMP4A	CHMP4B	0.998	0.1805
IST1	VPS9D1	0.998		structurally_consistent (dimer)
CHMP5	CHMP1A	0.998	0.192
CHMP1A	CHMP2A	0.998	0.144
PDCD6IP	MVB12A	0.997	0.118
VPS37B	UBAP1	0.997	0.046
IST1	CHMP4B	0.997	0.246
CHMP2A	CHMP4B	0.997	0.35
CHMP2B	CHMP4A	0.997	0.066	mutually_exclusive (Q9NZZ3)
VPS37B	MVB12A	0.997	0.268
MVB12A	VPS37C	0.997	0.106	structurally_consistent (Q9UK41) structurally_consistent (dimer)
UMAD1	VPS28	0.996	0.172
CHMP2A	CHMP1B	0.995	0.112	structurally_consistent (dimer)
CHMP5	CHMP4A	0.995	0.066	structurally_consistent (dimer)
CHMP1A	CHMP1B	0.995	0.108
CHMP3	CHMP2B	0.995	0.108	mutually_exclusive (O43633)
IST1	CHMP5	0.994	0.07
CHMP3	CHMP1A	0.994	0.094
CHMP2B	CHMP2A	0.993	0.17	structurally_consistent (dimer)
IST1	CHMP1A	0.993	0.172	structurally_consistent (dimer)
CHMP3	CHMP5	0.992	0.04
VPS37A	VPS37C	0.991	0.082
VPS37B	VPS37C	0.991	0.036
CD2AP	VPS37C	0.991	0.056
TSG101	CHMP4B	0.989	0.208
PDCD6IP	VPS37C	0.989	0.134773333333
TSG101	UMAD1	0.988	0.154
CD2AP	MVB12A	0.988	0.094
TSG101	CHMP4A	0.987	0.202
VPS37C	UBAP1	0.987	0.072
CHMP3	CHMP4A	0.986	0.108
CHMP5	CHMP1B	0.985	0.116
CHMP5	SPAST	0.984	0.044
TSG101	CHMP3	0.984	0.158
MVB12A	VPS37A	0.983	0.212
UMAD1	VPS37C	0.983	0.108
CHMP5	CHMP2B	0.983	0.122	structurally_consistent (dimer)
PDCD6IP	TSG101	0.982	0.246666666667
UMAD1	CHMP4B	0.981	0.082
UMAD1	MVB12A	0.981	0.054
MVB12A	UBAP1	0.981	0.08
IST1	CHMP3	0.98	0.238	structurally_consistent (Q7LBR1) structurally_consistent (dimer)
PDCD6IP	CHMP4B	0.977	0.468	structurally_consistent (dimer)
TSG101	PTPN23	0.976	0.186
CHMP5	CHMP2A	0.976	0.212	structurally_consistent (dimer)
PTPN23	CHMP1B	0.975	0.03
CHMP2A	SPAST	0.975	0.074
CHMP4B	VPS37C	0.974	0.246	structurally_consistent (Q9UK41)
MVB12B	MVB12A	0.972	0.052
UMAD1	CHMP2B	0.97	0.058
MVB12A	CHMP3	0.965	0.1
PDCD6IP	UMAD1	0.963	0.096
PDCD6IP	CHMP3	0.963	0.09
CHMP3	CHMP1B	0.963	0.172	structurally_consistent (dimer)
MITD1	CHMP4B	0.962	0.162
VPS37B	VPS37A	0.962	0.1
UMAD1	CHMP4A	0.962	0.068
CHMP1A	CHMP4A	0.96	0.128	mutually_exclusive (Q96FZ7)
PTPN23	SPAST	0.956	0.144
MVB12A	CHMP4B	0.952	0.072
MITD1	CD2AP	0.949	0.066
MVB12B	VPS37B	0.948	0.126
CHMP4A	CHMP2A	0.947	0.17
MITD1	PTPN23	0.946	0.102
CHMP1A	SPAST	0.946	0.094
CHMP1A	PTPN23	0.945	0.11
PDCD6IP	PDCD6	0.943	0.32
CHMP4A	PTPN23	0.942	0.044
CHMP3	SPAST	0.941	0.052
IST1	CHMP2B	0.941	0.234
IST1	CHMP2A	0.94	0.192
TSG101	PDCD6	0.94	0.136
CD2AP	CHMP4B	0.938	0.136
UMAD1	CHMP3	0.934	0.062
MVB12A	PDCD6	0.934	0.042
TSG101	CHMP5	0.932	0.06
CD2AP	PDCD6IP	0.93	0.162
TSG101	CHMP2B	0.928	0.186
PDCD6IP	CHMP4A	0.923	0.214
CD2AP	TSG101	0.919	0.066
CHMP4B	VPS28	0.918	0.092	structurally_consistent (dimer)
MVB12A	CHMP5	0.918	0.122
TSG101	IST1	0.914	0.2
VPS9D1	SPAST	0.903
MITD1	SPAST	0.896	0.062
PTPN23	BAZ2B	0.895	0.094
CD2AP	CHMP3	0.886	0.054
CHMP5	VPS37C	0.886	0.114
MVB12B	UBAP1	0.884	0.06
SPAST	CAPN7	0.877	0.04
CHMP2B	SPAST	0.872	0.048
MVB12A	TAS2R7	0.87
CHMP4B	SPAST	0.869	0.122
MVB12B	VPS37A	0.866	0.108
PDCD6IP	SPAST	0.861	0.092
TSG101	CHMP1B	0.859	0.072
TSG101	SPAST	0.849	0.114
CHMP4B	PTPN23	0.848	0.194	structurally_consistent (dimer)
UMAD1	UBAP1	0.844	0.124
VPS37B	UMAD1	0.844	0.062
UMAD1	VPS37A	0.844	0.084
MVB12B	TSG101	0.839	0.072
CHMP1A	GLIS2	0.835
CD2AP	SPAST	0.828	0.034
PDCD6	CHMP3	0.815	0.072
MVB12A	PSPN	0.805
VPS9D1	CHMP2A	0.796
UMAD1	CHMP2A	0.796	0.092
VPS9D1	CHMP1A	0.796		mutually_exclusive (P53990)
MITD1	VPS9D1	0.796
IST1	VPS37C	0.796	0.092
TSG101	CAPN7	0.796	0.044
CHMP4A	CHMP1B	0.796	0.094
VPS9D1	CHMP3	0.796
VPS9D1	CHMP5	0.796
IST1	CAPN7	0.796	0.064
VPS9D1	CHMP2B	0.796
MITD1	CHMP4A	0.796	0.086
CHMP1B	CAPN7	0.796	0.01
MITD1	MVB12A	0.781	0.07
BAZ2B	CAPN7	0.781	0.076
CHMP4A	BAZ2B	0.781	0.076
CHMP4A	CAPN7	0.781	0.032
CHMP1B	SPAST	0.781	0.03
PDCD6IP	VPS9D1	0.774
CHMP2B	CAPN7	0.774	0.048
MITD1	IST1	0.773	0.13
MITD1	CHMP2B	0.773	0.094
MITD1	CHMP2A	0.773	0.178
MITD1	CHMP1A	0.773	0.064
CHMP4B	CAPN7	0.772	0.1
CHMP4B	BAZ2B	0.768	0.12
CHMP5	CAPN7	0.764	0.038
CHMP2A	CAPN7	0.764	0.028
MITD1	TSG101	0.764	0.15
VPS9D1	CAPN7	0.764
MVB12A	IST1	0.764	0.088
CHMP1A	CAPN7	0.764	0.042
MITD1	CHMP5	0.764	0.116
MITD1	CHMP3	0.764	0.112
MITD1	CHMP1B	0.764	0.076
CHMP3	CAPN7	0.764	0.034
MITD1	CAPN7	0.764	0.05
PDCD6IP	CAPN7	0.764	0.102
CHMP2B	VPS37A	0.763	0.124
VPS9D1	CHMP4B	0.755
PTPN23	CAPN7	0.748	0.102
PDCD6IP	IST1	0.738	0.186
CD2AP	IST1	0.738	0.088
CD2AP	CHMP2A	0.735	0.074
CD2AP	CHMP2B	0.724	0.058
MVB12A	PTPN23	0.708	0.05
CD2AP	TAS2R7	0.701
MVB12B	PDCD6IP	0.696	0.046
UMAD1	PTPN23	0.685	0.16
MVB12A	CHMP2A	0.682	0.072
VPS37C	TAS2R7	0.671
CHMP3	VPS37C	0.659	0.038
MVB12A	CHMP1A	0.641	0.114
MVB12B	VPS37C	0.63	0.07
TSG101	CHMP1A	0.624	0.14
VPS37C	SPAST	0.624	0.092
CD2AP	PDCD6	0.612	0.046
MITD1	PDCD6IP	0.61	0.122
PDCD6IP	BAZ2B	0.608	0.088
CHMP2A	PTPN23	0.595	0.226
CHMP5	BAZ2B	0.594	0.054
CHMP2B	UBAP1	0.589	0.094
CHMP2B	CHMP1B	0.583	0.11	mutually_exclusive (O43633)
PDCD6	VPS28	0.553	0.146
TSG101	CHMP2A	0.546	0.198
MVB12A	VPS9D1	0.545
MVB12A	CHMP2B	0.538	0.018
PDCD6	CHMP4B	0.535	0.282
IST1	CHMP4A	0.533	0.188
TSG101	TAS2R7	0.532
CHMP5	PTPN23	0.531	0.054
CHMP2B	VPS37C	0.516	0.062
PDCD6IP	CHMP2A	0.503	0.336
SPAST	BAZ2B	0.483	0.128
TSG101	VPS9D1	0.483
CHMP3	BAZ2B	0.483	0.066
CHMP1B	BAZ2B	0.483	0.056
TSG101	BAZ2B	0.483	0.06
VPS9D1	CHMP1B	0.483
CD2AP	VPS9D1	0.483
MVB12A	CAPN7	0.483	0.032
CD2AP	CHMP1A	0.448	0.086
CHMP2B	BAZ2B	0.433	0.12
VPS37B	CHMP2B	0.422	0.068
CHMP3	PTPN23	0.42	0.124
UMAD1	TAS2R7	0.413
IST1	PTPN23	0.409	0.188
UMAD1	PDCD6	0.404	0.104
CD2AP	CHMP5	0.37	0.058
MVB12A	SPAST	0.368	0.058
UMAD1	CHMP1B	0.351	0.072
CD2AP	CAPN7	0.351	0.016
CHMP4A	SPAST	0.351	0.052
MITD1	BAZ2B	0.351	0.05
PDCD6IP	TAS2R7	0.332
PDCD6	VPS37C	0.313	0.072
CHMP2A	BAZ2B	0.288	0.054
UMAD1	CHMP5	0.288	0.088
CHMP1A	BAZ2B	0.288	0.046
CHMP2B	PTPN23	0.276	0.13
PDCD6IP	CHMP2B	0.259	0.161
VPS9D1	PTPN23	0.232
UMAD1	CAPN7	0.232	0.034
UMAD1	BAZ2B	0.232	0.05
VPS9D1	CHMP4A	0.232
VPS37C	CAPN7	0.232	0.042
VPS9D1	VPS37C	0.232
CD2AP	VPS28	0.227	0.072
MITD1	UMAD1	0.226	0.104
MITD1	VPS37C	0.226	0.096
VPS37B	PTPN23	0.211	0.104
CD2AP	UMAD1	0.194	0.098
PDCD6IP	VPS28	0.193	0.124
VPS9D1	BAZ2B	0.192
PDCD6	PSPN	0.19
CHMP5	VPS37A	0.177	0.326
PDCD6	CHMP2B	0.177	0.078
PDCD6IP	CHMP1A	0.175	0.076
CHMP3	VPS28	0.17	0.136
PTPN23	VPS28	0.169	0.11
CHMP5	UBAP1	0.154	0.162
MVB12B	CD2AP	0.151	0.102
PDCD6	CAPN7	0.149	0.024
UMAD1	CHMP1A	0.149	0.118
CHMP2A	VPS37C	0.149	0.122
CHMP1A	VPS37C	0.149	0.124
PDCD6	VPS9D1	0.149
CD2AP	CHMP1B	0.142	0.044
CD2AP	CHMP4A	0.133	0.062
CHMP2B	VPS28	0.128	0.144
CHMP4B	VPS37A	0.126	0.242
PDCD6IP	PSPN	0.118
MVB12B	PDCD6	0.116	0.042
VPS37B	CHMP4B	0.113	0.1
CD2AP	BAZ2B	0.098	0.086
MVB12B	CHMP4B	0.094	0.0533333333333
PDCD6	CHMP1A	0.091	0.09
MVB12B	CHMP3	0.089	0.058
MVB12B	UMAD1	0.089	0.166
PDCD6	CHMP4A	0.087	0.164
CHMP4B	UBAP1	0.081	0.094
PDCD6	GLIS2	0.077
PDCD6IP	CHMP1B	0.072	0.122
VPS37B	CHMP3	0.063	0.066
MVB12A	BAZ2B	0.063	0.068
CHMP3	VPS37A	0.063	0.134
CHMP3	UBAP1	0.063	0.098
VPS37B	CHMP5	0.054	0.042
CHMP4A	VPS28	0.053	0.09
TSG101	PSPN	0.053
PDCD6	UBAP1	0.052	0.072
PDCD6IP	PTPN23	0.05	0.234	mutually_exclusive (Q9H444)
MVB12A	CHMP4A	0.049	0.042
IST1	VPS37A	0.049	0.144
VPS37B	IST1	0.049	0.216	mutually_exclusive (O75340)
IST1	UBAP1	0.049	0.08
PDCD6	SPAST	0.048	0.08
MITD1	PDCD6	0.048	0.162
UMAD1	SPAST	0.048	0.114
PDCD6IP	CHMP5	0.043	0.264
PDCD6	CHMP2A	0.043	0.33
IST1	BAZ2B	0.039	0.07
CD2AP	PSPN	0.038
PDCD6	PTPN23	0.037	0.036
PDCD6	BAZ2B	0.034	0.132
MVB12A	CHMP1B	0.034	0.046
UMAD1	IST1	0.034	0.112
IST1	VPS28	0.034	0.23
CHMP5	TAS2R7	0.03
PDCD6	VPS37A	0.029	0.13
CHMP4B	TAS2R7	0.027
CHMP4B	GLIS2	0.025
CHMP5	VPS28	0.025	0.094
PDCD6IP	UBAP1	0.025	0.148
PDCD6	TAS2R7	0.022
PTPN23	VPS37A	0.019	0.106
PDCD6IP	GLIS2	0.017
PTPN23	UBAP1	0.016	0.08
VPS37B	CHMP1B	0.014	0.092
VPS37B	PDCD6	0.013	0.054	structurally_consistent (dimer)
CHMP5	PSPN	0.012
CHMP4B	PSPN	0.012
CD2AP	VPS37A	0.011	0.078
PTPN23	VPS37C	0.01	0.092
VPS37B	PDCD6IP	0.01	0.11
CD2AP	PTPN23	0.006	0.078
PDCD6IP	VPS37A	0.006	0.356
CD2AP	VPS37B	0.006	0.064
PDCD6	CHMP1B	0.006	0.084
CD2AP	UBAP1	0.005	0.234
PDCD6	CHMP5	0.004	0.13
PDCD6	IST1	0.002	0.196	structurally_consistent (dimer)

Related Complexes

Genename	Complexes
TAS2R7	huMAP3_12564.1 huMAP3_12917.1 huMAP3_13805.1 huMAP3_15286.1
VPS9D1	huMAP3_02537.1 huMAP3_04368.1 huMAP3_06462.1 huMAP3_10053.1 huMAP3_13805.1 huMAP3_14298.1 huMAP3_15106.1
VPS28	huMAP3_04792.1 huMAP3_06010.1 huMAP3_06533.1 huMAP3_07951.1 huMAP3_09572.1 huMAP3_12917.1 huMAP3_13805.1
TSG101	huMAP3_01514.1 huMAP3_06010.1 huMAP3_07951.1 huMAP3_08679.1 huMAP3_09572.1 huMAP3_10053.1 huMAP3_12917.1 huMAP3_13805.1
UMAD1	huMAP3_01514.1 huMAP3_03988.1 huMAP3_06010.1 huMAP3_06564.1 huMAP3_07951.1 huMAP3_08679.1 huMAP3_09572.1 huMAP3_10053.1 huMAP3_12917.1 huMAP3_13805.1
CHMP4A	huMAP3_03988.1 huMAP3_06564.1 huMAP3_08679.1 huMAP3_10053.1 huMAP3_13805.1 huMAP3_14442.1
CD2AP	huMAP3_00688.1 huMAP3_01443.1 huMAP3_06016.1 huMAP3_07667.1 huMAP3_11326.1 huMAP3_12900.1 huMAP3_13310.1 huMAP3_13805.1
CAPN7	huMAP3_12477.1 huMAP3_13805.1 huMAP3_14298.1 huMAP3_15106.1
PDCD6IP	huMAP3_01514.1 huMAP3_03988.1 huMAP3_06010.1 huMAP3_06089.1 huMAP3_06564.1 huMAP3_07951.1 huMAP3_08679.1 huMAP3_09572.1 huMAP3_10053.1 huMAP3_12409.1 huMAP3_12917.1 huMAP3_13805.1
CHMP2A	huMAP3_03988.1 huMAP3_06564.1 huMAP3_08679.1 huMAP3_10053.1 huMAP3_13805.1
VPS37A	huMAP3_04888.1 huMAP3_09572.1 huMAP3_12917.1 huMAP3_13805.1
CHMP3	huMAP3_03034.1 huMAP3_06564.1 huMAP3_08679.1 huMAP3_10053.1 huMAP3_13805.1
CHMP1A	huMAP3_03034.1 huMAP3_06564.1 huMAP3_08679.1 huMAP3_10053.1 huMAP3_12724.1 huMAP3_13805.1
MVB12B	huMAP3_00501.1 huMAP3_04792.1 huMAP3_06010.1 huMAP3_06241.1 huMAP3_06316.1 huMAP3_07951.1 huMAP3_08364.1 huMAP3_09572.1 huMAP3_10226.1 huMAP3_12917.1 huMAP3_13805.1
CHMP2B	huMAP3_03988.1 huMAP3_06564.1 huMAP3_08679.1 huMAP3_10053.1 huMAP3_12523.1 huMAP3_13805.1
PSPN	huMAP3_12917.1 huMAP3_13805.1
IST1	huMAP3_02537.1 huMAP3_10053.1 huMAP3_13805.1
BAZ2B	huMAP3_12452.1 huMAP3_13805.1
MVB12A	huMAP3_01514.1 huMAP3_06010.1 huMAP3_07951.1 huMAP3_09572.1 huMAP3_12917.1 huMAP3_13805.1
PTPN23	huMAP3_04286.1 huMAP3_10890.1 huMAP3_12452.1 huMAP3_13805.1
CHMP4B	huMAP3_03988.1 huMAP3_06564.1 huMAP3_08679.1 huMAP3_10053.1 huMAP3_13805.1
VPS37B	huMAP3_01514.1 huMAP3_06010.1 huMAP3_07951.1 huMAP3_09572.1 huMAP3_12917.1 huMAP3_13805.1
CHMP5	huMAP3_03034.1 huMAP3_06564.1 huMAP3_08679.1 huMAP3_10053.1 huMAP3_13805.1
SPAST	huMAP3_07492.1 huMAP3_07705.1 huMAP3_09710.1 huMAP3_13805.1
VPS37C	huMAP3_06533.1 huMAP3_09572.1 huMAP3_12303.1 huMAP3_12658.1 huMAP3_12917.1 huMAP3_13805.1
CHMP1B	huMAP3_06564.1 huMAP3_08679.1 huMAP3_10053.1 huMAP3_11896.1 huMAP3_12719.1 huMAP3_13805.1 huMAP3_15175.1
MITD1	huMAP3_00243.1 huMAP3_00738.1 huMAP3_02301.1 huMAP3_05627.1 huMAP3_13728.1 huMAP3_13805.1
PDCD6	huMAP3_01795.1 huMAP3_12051.1 huMAP3_12917.1 huMAP3_13805.1
GLIS2	huMAP3_04015.1 huMAP3_07210.1 huMAP3_13259.1 huMAP3_13696.1 huMAP3_13805.1 huMAP3_13913.1 huMAP3_14779.1 huMAP3_14854.1
UBAP1	huMAP3_07951.1 huMAP3_09572.1 huMAP3_12917.1 huMAP3_13805.1

hu.MAP 3.0: Complex View

Search for a protein

Complex: huMAP3_13805.1

Complex Portal: CPX-21196