hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_13808.1
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| KLHL1 | Kelch-like protein 1 | 4 | UniProt NCBI |
| HENMT1 | Small RNA 2'-O-methyltransferase (EC 2.1.1.386) (HEN1 methyltransferase homolog 1) | 5 | UniProt NCBI |
| PAMR1 | Inactive serine protease PAMR1 (Peptidase domain-containing protein associated with muscle regeneration 1) (Regeneration-associated muscle protease homolog) | 4 | UniProt NCBI |
| SNX5 | Sorting nexin-5 | 5 | UniProt NCBI |
| SNX6 | Sorting nexin-6 (TRAF4-associated factor 2) [Cleaved into: Sorting nexin-6, N-terminally processed] | 5 | UniProt NCBI |
| ARHGEF37 | Rho guanine nucleotide exchange factor 37 | 2 | UniProt NCBI |
| BMP6 | Bone morphogenetic protein 6 (BMP-6) (VG-1-related protein) (VG-1-R) (VGR-1) | 5 | UniProt NCBI |
| SNX1 | Sorting nexin-1 | 5 | UniProt NCBI |
| HEPACAM | Hepatic and glial cell adhesion molecule (glialCAM) (Hepatocyte cell adhesion molecule) (Protein hepaCAM) | 5 | UniProt NCBI |
| SNX2 | Sorting nexin-2 (Transformation-related gene 9 protein) (TRG-9) | 5 | UniProt NCBI |
| DNMBP | Dynamin-binding protein (Scaffold protein Tuba) | 5 | UniProt NCBI |
| C1orf87 | Uncharacterized protein C1orf87 | 2 | UniProt NCBI |
| IGFBPL1 | Insulin-like growth factor-binding protein-like 1 (IGFBP-related protein 10) (Insulin-like growth factor-binding-related protein 4) (IGFBP-rP4) | 4 | UniProt NCBI |
| ZBTB3 | Zinc finger and BTB domain-containing protein 3 | 3 | UniProt NCBI |
| SNX32 | Sorting nexin-32 (Sorting nexin-6B) | 5 | UniProt NCBI |
| BIN3 | Bridging integrator 3 | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0030905 | 4.78889884367e-08 | 0.25 | SNX2 SNX6 SNX5 SNX1 | retromer, tubulation complex |
| CORUM:1058 | 5.10764421909e-05 | 0.125 | SNX6 SNX1 | SNX complex (SNX1, SNX6) |
| CORUM:1070 | 0.000153131458895 | 0.125 | SNX1 SNX2 | SNX complex (SNX1, SNX1a, SNX2, SNX4) |
| CORUM:1096 | 0.000153131458895 | 0.125 | SNX1 SNX2 | SNX complex (SNX1, SNX1a, SNX2, SNX4, PDGFRA) |
| GO:0030904 | 0.000183796361517 | 0.25 | SNX2 SNX6 SNX5 SNX1 | retromer complex |
| KEGG:04144 | 0.000212315112623 | 0.3125 | SNX2 SNX6 SNX32 SNX5 SNX1 | Endocytosis |
| CORUM:1091 | 0.000306067313039 | 0.125 | SNX1 SNX2 | SNX complex (SNX1, SNX1a, SNX2, SNX4, LEPR) |
| CORUM:1093 | 0.000306067313039 | 0.125 | SNX1 SNX2 | SNX complex (SNX1, SNX1a, SNX2, SNX4, INSR) |
| CORUM:1095 | 0.000306067313039 | 0.125 | SNX1 SNX2 | SNX complex (SNX1, SNX1a, SNX2, SNX4, EGFR) |
| CORUM:657 | 0.000509786398016 | 0.125 | SNX1 SNX2 | Retromer complex (SNX1, SNX2, VPS35, VPS29, VPS26A) |
| CORUM:1059 | 0.000509786398016 | 0.125 | SNX1 SNX2 | Retromer complex (SNX1, SNX2, VPS35, VPS29, VPS26A) |
| CORUM:1060 | 0.000509786398016 | 0.125 | SNX1 SNX2 | Retromer complex (SNX1, SNX2, VPS35, VPS29, VPS26B) |
| GO:0042147 | 0.00115540580919 | 0.3125 | SNX2 SNX6 SNX32 SNX5 SNX1 | retrograde transport, endosome to Golgi |
| GO:0016482 | 0.00668623538924 | 0.3125 | SNX2 SNX6 SNX32 SNX5 SNX1 | cytosolic transport |
| CORUM:1072 | 0.0497620750785 | 0.0625 | SNX2 | SNX complex (SNX2), oligomeric |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD |
|---|---|---|---|
| SNX5 | SNX1 | 1.0 | 0.326 |
| SNX6 | SNX1 | 1.0 | 0.562 |
| SNX1 | SNX2 | 1.0 | 0.378 |
| SNX1 | SNX32 | 0.999 | |
| ARHGEF37 | BIN3 | 0.999 | |
| C1orf87 | SNX5 | 0.998 | |
| BIN3 | DNMBP | 0.998 | 0.44 |
| C1orf87 | SNX2 | 0.998 | |
| SNX6 | SNX2 | 0.997 | 0.384 |
| BIN3 | SNX1 | 0.997 | 0.05 |
| C1orf87 | SNX1 | 0.996 | |
| SNX6 | SNX32 | 0.996 | |
| C1orf87 | HEPACAM | 0.995 | |
| KLHL1 | SNX2 | 0.994 | |
| PAMR1 | SNX1 | 0.992 | |
| SNX2 | SNX32 | 0.987 | |
| SNX5 | SNX2 | 0.984 | 0.33 |
| KLHL1 | SNX1 | 0.953 | |
| SNX2 | HENMT1 | 0.928 | |
| SNX5 | IGFBPL1 | 0.919 | 0.048 |
| PAMR1 | SNX32 | 0.902 | |
| BIN3 | PAMR1 | 0.902 | |
| ARHGEF37 | DNMBP | 0.899 | |
| SNX1 | BMP6 | 0.894 | |
| SNX1 | IGFBPL1 | 0.891 | 0.098 |
| SNX2 | BMP6 | 0.875 | |
| KLHL1 | SNX6 | 0.869 | |
| BIN3 | SNX5 | 0.867 | 0.066 |
| SNX5 | SNX6 | 0.865 | 0.146 |
| SNX6 | IGFBPL1 | 0.862 | 0.064 |
| SNX6 | BMP6 | 0.861 | |
| PAMR1 | SNX5 | 0.86 | |
| SNX6 | HENMT1 | 0.853 | |
| BIN3 | SNX32 | 0.839 | |
| SNX2 | IGFBPL1 | 0.818 | 0.094 |
| SNX5 | SNX32 | 0.73 | |
| PAMR1 | SNX6 | 0.715 | |
| BIN3 | SNX6 | 0.45 | 0.082 |
| ARHGEF37 | SNX1 | 0.45 | |
| PAMR1 | SNX2 | 0.356 | |
| HEPACAM | SNX5 | 0.29 | |
| BIN3 | SNX2 | 0.24 | 0.112 |
| DNMBP | SNX1 | 0.171 | 0.074 |
| HEPACAM | SNX1 | 0.164 | |
| ARHGEF37 | SNX5 | 0.161 | |
| HEPACAM | SNX2 | 0.143 | |
| SNX1 | HENMT1 | 0.142 | |
| DNMBP | SNX5 | 0.076 | 0.022 |
| DNMBP | SNX6 | 0.029 | 0.104 |
| DNMBP | SNX2 | 0.004 | 0.068 |
Related Complexes