hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_13817.1
Complex Portal: CPX-15613
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| ZC2HC1C | Zinc finger C2HC domain-containing protein 1C | 5 | UniProt NCBI |
| IFT25 | Intraflagellar transport protein 25 homolog (Heat shock protein beta-11) (Hspb11) (Placental protein 25) (PP25) | 5 | UniProt NCBI |
| KATNIP | Katanin-interacting protein | 5 | UniProt NCBI |
| IFT88 | Intraflagellar transport protein 88 homolog (Recessive polycystic kidney disease protein Tg737 homolog) (Tetratricopeptide repeat protein 10) (TPR repeat protein 10) | 5 | UniProt NCBI |
| IFT81 | Intraflagellar transport protein 81 homolog (Carnitine deficiency-associated protein expressed in ventricle 1) (CDV-1) | 5 | UniProt NCBI |
| IFT74 | Intraflagellar transport protein 74 homolog (Capillary morphogenesis gene 1 protein) (CMG-1) (Coiled-coil domain-containing protein 2) | 5 | UniProt NCBI |
| IFT80 | Intraflagellar transport protein 80 homolog (WD repeat-containing protein 56) | 5 | UniProt NCBI |
| IFT46 | Intraflagellar transport protein 46 homolog | 5 | UniProt NCBI |
| IFT56 | Intraflagellar transport protein 56 (Tetratricopeptide repeat protein 26) (TPR repeat protein 26) | 5 | UniProt NCBI |
| IFT22 | Intraflagellar transport protein 22 homolog (Rab-like protein 5) | 4 | UniProt NCBI |
| CLUAP1 | Clusterin-associated protein 1 (Qilin) | 5 | UniProt NCBI |
| TFPI2 | Tissue factor pathway inhibitor 2 (TFPI-2) (Placental protein 5) (PP5) | 5 | UniProt NCBI |
| IFT70B | Intraflagellar transport protein 70B (Tetratricopeptide repeat protein 30B) (TPR repeat protein 30B) | 4 | UniProt NCBI |
| IFT70A | Intraflagellar transport protein 70A (Tetratricopeptide repeat protein 30A) (TPR repeat protein 30A) | 3 | UniProt NCBI |
| IFT57 | Intraflagellar transport protein 57 homolog (Dermal papilla-derived protein 8) (Estrogen-related receptor beta-like protein 1) (HIP1-interacting protein) (MHS4R2) | 5 | UniProt NCBI |
| IFT172 | Intraflagellar transport protein 172 homolog | 5 | UniProt NCBI |
| TRAF3IP1 | TRAF3-interacting protein 1 (Interleukin-13 receptor alpha 1-binding protein 1) (Intraflagellar transport protein 54 homolog) (Microtubule-interacting protein associated with TRAF3) (MIP-T3) | 5 | UniProt NCBI |
| IFT52 | Intraflagellar transport protein 52 homolog (Protein NGD5 homolog) | 5 | UniProt NCBI |
| IFT27 | Intraflagellar transport protein 27 homolog (Putative GTP-binding protein RAY-like) (Rab-like protein 4) | 5 | UniProt NCBI |
| IFT20 | Intraflagellar transport protein 20 homolog (hIFT20) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0030992 | 3.23151583623e-49 | 0.85 | IFT25 CLUAP1 IFT46 IFT56 IFT88 IFT74 IFT80 TRAF3IP1 IFT27 IFT81 IFT22 IFT57 IFT70B IFT20 IFT70A IFT52 IFT172 | intraciliary transport particle B |
| CORUM:6172 | 2.51380560409e-45 | 0.75 | IFT25 IFT46 IFT56 IFT88 IFT74 IFT80 TRAF3IP1 IFT27 IFT81 IFT22 IFT57 IFT70B IFT20 IFT52 IFT172 | Intraflagellar transport complex B |
| GO:0030990 | 3.25832064655e-44 | 0.85 | IFT25 CLUAP1 IFT46 IFT56 IFT88 IFT74 IFT80 TRAF3IP1 IFT27 IFT81 IFT22 IFT57 IFT70B IFT20 IFT70A IFT52 IFT172 | intraciliary transport particle |
| GO:0035720 | 1.80358582702e-43 | 0.8 | IFT25 CLUAP1 IFT46 IFT56 IFT88 IFT74 IFT80 TRAF3IP1 IFT27 IFT81 IFT22 IFT57 IFT70B IFT20 IFT52 IFT172 | intraciliary anterograde transport |
| REAC:R-HSA-5620924 | 2.94525617681e-38 | 0.85 | IFT25 CLUAP1 IFT46 IFT56 IFT88 IFT74 IFT80 TRAF3IP1 IFT27 IFT81 IFT22 IFT57 IFT70B IFT20 IFT70A IFT52 IFT172 | Intraflagellar transport |
| GO:0042073 | 8.18957126396e-38 | 0.85 | IFT25 CLUAP1 IFT46 IFT56 IFT88 IFT74 IFT80 TRAF3IP1 IFT27 IFT81 IFT22 IFT57 IFT70B IFT20 IFT70A IFT52 IFT172 | intraciliary transport |
| GO:0097542 | 7.56957892911e-34 | 0.8 | IFT25 CLUAP1 IFT46 IFT56 IFT88 IFT74 IFT80 TRAF3IP1 IFT27 IFT81 IFT22 IFT57 IFT70B IFT20 IFT52 IFT172 | ciliary tip |
| CORUM:6173 | 5.52026999037e-29 | 0.5 | IFT25 IFT46 IFT56 IFT88 IFT74 IFT27 IFT81 IFT22 IFT70B IFT52 | Intraflagellar transport complex B core complex |
| GO:0031503 | 1.26438471628e-28 | 0.85 | IFT25 CLUAP1 IFT46 IFT56 IFT88 IFT74 IFT80 TRAF3IP1 IFT27 IFT81 IFT22 IFT57 IFT70B IFT20 IFT70A IFT52 IFT172 | protein-containing complex localization |
| GO:0010970 | 5.82669983388e-28 | 0.85 | IFT25 CLUAP1 IFT46 IFT56 IFT88 IFT74 IFT80 TRAF3IP1 IFT27 IFT81 IFT22 IFT57 IFT70B IFT20 IFT70A IFT52 IFT172 | transport along microtubule |
| WP:WP5381 | 1.20474513536e-27 | 0.8 | IFT25 CLUAP1 IFT46 IFT56 IFT88 IFT74 IFT80 TRAF3IP1 IFT27 IFT81 IFT22 IFT57 IFT70B IFT20 IFT52 IFT172 | Smith Magenis and Potocki Lupski syndrome copy number variation |
| REAC:R-HSA-5617833 | 1.30245152242e-27 | 0.85 | IFT25 CLUAP1 IFT46 IFT56 IFT88 IFT74 IFT80 TRAF3IP1 IFT27 IFT81 IFT22 IFT57 IFT70B IFT20 IFT70A IFT52 IFT172 | Cilium Assembly |
| WP:WP4536 | 1.51271218884e-27 | 0.75 | IFT25 IFT46 IFT56 IFT88 IFT74 IFT80 TRAF3IP1 IFT27 IFT81 CLUAP1 IFT57 IFT70B IFT20 IFT52 IFT172 | Genes related to primary cilium development based on CRISPR |
| WP:WP4352 | 3.06715489857e-27 | 0.85 | IFT25 CLUAP1 IFT46 IFT56 IFT88 IFT74 IFT80 TRAF3IP1 IFT27 IFT81 IFT22 IFT57 IFT70B IFT20 IFT70A IFT52 IFT172 | Ciliary landscape |
| GO:0099111 | 4.85132886393e-27 | 0.85 | IFT25 CLUAP1 IFT46 IFT56 IFT88 IFT74 IFT80 TRAF3IP1 IFT27 IFT81 IFT22 IFT57 IFT70B IFT20 IFT70A IFT52 IFT172 | microtubule-based transport |
| GO:0030705 | 4.35603302881e-26 | 0.85 | IFT25 CLUAP1 IFT46 IFT56 IFT88 IFT74 IFT80 TRAF3IP1 IFT27 IFT81 IFT22 IFT57 IFT70B IFT20 IFT70A IFT52 IFT172 | cytoskeleton-dependent intracellular transport |
| REAC:R-HSA-1852241 | 9.52859623643e-25 | 0.85 | IFT25 CLUAP1 IFT46 IFT56 IFT88 IFT74 IFT80 TRAF3IP1 IFT27 IFT81 IFT22 IFT57 IFT70B IFT20 IFT70A IFT52 IFT172 | Organelle biogenesis and maintenance |
| GO:0007018 | 1.18772473856e-22 | 0.85 | IFT25 CLUAP1 IFT46 IFT56 IFT88 IFT74 IFT80 TRAF3IP1 IFT27 IFT81 IFT22 IFT57 IFT70B IFT20 IFT70A IFT52 IFT172 | microtubule-based movement |
| GO:0044782 | 4.9194433226e-22 | 0.85 | IFT25 CLUAP1 IFT46 IFT56 IFT88 IFT74 IFT80 TRAF3IP1 IFT27 IFT81 IFT22 IFT57 IFT70B IFT20 IFT70A IFT52 IFT172 | cilium organization |
| GO:0060271 | 3.40430039122e-20 | 0.8 | IFT25 CLUAP1 IFT46 IFT56 IFT88 IFT74 IFT80 TRAF3IP1 IFT27 IFT81 IFT22 IFT57 IFT70B IFT20 IFT52 IFT172 | cilium assembly |
| GO:0005929 | 4.53516254134e-19 | 0.85 | IFT25 CLUAP1 IFT46 IFT56 IFT88 IFT74 IFT80 TRAF3IP1 IFT27 IFT81 IFT22 IFT57 IFT70B IFT20 IFT70A IFT52 IFT172 | cilium |
| GO:0120031 | 1.75207495301e-17 | 0.8 | IFT25 CLUAP1 IFT46 IFT56 IFT88 IFT74 IFT80 TRAF3IP1 IFT27 IFT81 IFT22 IFT57 IFT70B IFT20 IFT52 IFT172 | plasma membrane bounded cell projection assembly |
| GO:0030031 | 2.60838357846e-17 | 0.8 | IFT25 CLUAP1 IFT46 IFT56 IFT88 IFT74 IFT80 TRAF3IP1 IFT27 IFT81 IFT22 IFT57 IFT70B IFT20 IFT52 IFT172 | cell projection assembly |
| GO:0007017 | 1.31011864592e-15 | 0.85 | IFT25 CLUAP1 IFT46 IFT56 IFT88 IFT74 IFT80 TRAF3IP1 IFT27 IFT81 IFT22 IFT57 IFT70B IFT20 IFT70A IFT52 IFT172 | microtubule-based process |
| WP:WP5234 | 3.37530007535e-14 | 0.45 | IFT172 CLUAP1 IFT80 IFT74 TRAF3IP1 IFT81 IFT27 IFT57 IFT52 | Bardet Biedl syndrome |
| CORUM:6174 | 1.01900785471e-13 | 0.25 | IFT57 IFT20 IFT80 TRAF3IP1 IFT172 | Intraflagellar transport complex B peripheral subcomplex |
| GO:0070925 | 2.74730594572e-13 | 0.8 | IFT25 CLUAP1 IFT46 IFT56 IFT88 IFT74 IFT80 TRAF3IP1 IFT27 IFT81 IFT22 IFT57 IFT70B IFT20 IFT52 IFT172 | organelle assembly |
| GO:0120036 | 3.49672695154e-13 | 0.85 | IFT25 CLUAP1 IFT46 IFT56 IFT88 IFT74 IFT80 TRAF3IP1 IFT27 IFT81 IFT22 IFT57 IFT70B IFT20 IFT70A IFT52 IFT172 | plasma membrane bounded cell projection organization |
| GO:0030030 | 4.38749798159e-13 | 0.85 | IFT25 CLUAP1 IFT46 IFT56 IFT88 IFT74 IFT80 TRAF3IP1 IFT27 IFT81 IFT22 IFT57 IFT70B IFT20 IFT70A IFT52 IFT172 | cell projection organization |
| GO:0046907 | 2.42967671041e-12 | 0.85 | IFT25 CLUAP1 IFT46 IFT56 IFT88 IFT74 IFT80 TRAF3IP1 IFT27 IFT81 IFT22 IFT57 IFT70B IFT20 IFT70A IFT52 IFT172 | intracellular transport |
| GO:0120025 | 1.67537441297e-11 | 0.85 | IFT25 CLUAP1 IFT46 IFT56 IFT88 IFT74 IFT80 TRAF3IP1 IFT27 IFT81 IFT22 IFT57 IFT70B IFT20 IFT70A IFT52 IFT172 | plasma membrane bounded cell projection |
| GO:0042995 | 1.97805059325e-11 | 0.85 | IFT25 CLUAP1 IFT46 IFT56 IFT88 IFT74 IFT80 TRAF3IP1 IFT27 IFT81 IFT22 IFT57 IFT70B IFT20 IFT70A IFT52 IFT172 | cell projection |
| WP:WP4803 | 2.67403644372e-11 | 0.45 | IFT172 CLUAP1 IFT80 TRAF3IP1 KATNIP IFT27 IFT57 IFT52 IFT81 | Ciliopathies |
| WP:WP4532 | 1.02965751503e-10 | 0.3 | IFT25 IFT46 IFT22 IFT80 IFT81 IFT27 | Intraflagellar transport proteins binding to dynein |
| HP:0010442 | 1.40566541878e-10 | 0.5 | IFT56 IFT172 IFT27 IFT74 IFT80 TRAF3IP1 KATNIP IFT57 IFT52 IFT81 | Polydactyly |
| GO:0051649 | 1.62177766933e-10 | 0.85 | IFT25 CLUAP1 IFT46 IFT56 IFT88 IFT74 IFT80 TRAF3IP1 IFT27 IFT81 IFT22 IFT57 IFT70B IFT20 IFT70A IFT52 IFT172 | establishment of localization in cell |
| GO:0015630 | 2.09909381949e-09 | 0.75 | IFT25 IFT46 IFT56 IFT88 IFT74 IFT80 TRAF3IP1 IFT81 CLUAP1 IFT57 IFT70B IFT20 IFT70A IFT52 IFT172 | microtubule cytoskeleton |
| HP:0100259 | 3.3524220285e-09 | 0.4 | IFT56 IFT172 IFT27 IFT80 IFT74 IFT81 IFT57 IFT52 | Postaxial polydactyly |
| GO:0005815 | 5.87652464429e-09 | 0.65 | IFT25 IFT46 IFT56 IFT88 IFT74 IFT80 TRAF3IP1 IFT81 CLUAP1 IFT57 IFT20 IFT52 IFT172 | microtubule organizing center |
| GO:0097546 | 6.68096060174e-08 | 0.3 | IFT56 IFT88 TRAF3IP1 IFT20 IFT57 IFT52 | ciliary base |
| WP:WP5202 | 6.78280860939e-08 | 0.25 | IFT25 IFT27 IFT81 IFT172 IFT74 | Alstrom syndrome |
| GO:0036064 | 9.46188006756e-08 | 0.4 | IFT56 IFT172 IFT88 IFT20 TRAF3IP1 IFT81 IFT57 IFT46 | ciliary basal body |
| GO:0005856 | 8.28523891577e-07 | 0.75 | IFT25 IFT46 IFT56 IFT88 IFT74 IFT80 TRAF3IP1 IFT81 CLUAP1 IFT57 IFT70B IFT20 IFT70A IFT52 IFT172 | cytoskeleton |
| GO:0051641 | 1.36230742299e-06 | 0.85 | IFT25 CLUAP1 IFT46 IFT56 IFT88 IFT74 IFT80 TRAF3IP1 IFT27 IFT81 IFT22 IFT57 IFT70B IFT20 IFT70A IFT52 IFT172 | cellular localization |
| GO:0022607 | 9.13848075776e-06 | 0.8 | IFT25 CLUAP1 IFT46 IFT56 IFT88 IFT74 IFT80 TRAF3IP1 IFT27 IFT81 IFT22 IFT57 IFT70B IFT20 IFT52 IFT172 | cellular component assembly |
| GO:0006996 | 1.42797937088e-05 | 0.85 | IFT25 CLUAP1 IFT46 IFT56 IFT88 IFT74 IFT80 TRAF3IP1 IFT27 IFT81 IFT22 IFT57 IFT70B IFT20 IFT70A IFT52 IFT172 | organelle organization |
| HP:0001395 | 1.52256295192e-05 | 0.3 | IFT56 IFT172 IFT27 IFT74 IFT80 TRAF3IP1 | Hepatic fibrosis |
| GO:0006810 | 1.58917065815e-05 | 0.85 | IFT25 CLUAP1 IFT46 IFT56 IFT88 IFT74 IFT80 TRAF3IP1 IFT27 IFT81 IFT22 IFT57 IFT70B IFT20 IFT70A IFT52 IFT172 | transport |
| GO:0005813 | 2.99600848152e-05 | 0.5 | IFT25 IFT46 IFT88 IFT74 IFT80 TRAF3IP1 IFT81 CLUAP1 IFT57 IFT20 | centrosome |
| GO:0044085 | 3.73900648511e-05 | 0.8 | IFT25 CLUAP1 IFT46 IFT56 IFT88 IFT74 IFT80 TRAF3IP1 IFT27 IFT81 IFT22 IFT57 IFT70B IFT20 IFT52 IFT172 | cellular component biogenesis |
| GO:0051234 | 7.04794346703e-05 | 0.85 | IFT25 CLUAP1 IFT46 IFT56 IFT88 IFT74 IFT80 TRAF3IP1 IFT27 IFT81 IFT22 IFT57 IFT70B IFT20 IFT70A IFT52 IFT172 | establishment of localization |
| GO:0120170 | 0.000109576846827 | 0.15 | IFT56 IFT70A IFT70B | intraciliary transport particle B binding |
| HP:0001156 | 0.000193130000055 | 0.35 | IFT172 IFT27 IFT80 IFT74 IFT81 IFT57 IFT52 | Brachydactyly |
| HP:0001159 | 0.000349911851133 | 0.35 | IFT56 IFT172 IFT27 IFT80 IFT74 IFT81 IFT52 | Syndactyly |
| HP:0001829 | 0.000505917754493 | 0.25 | IFT27 IFT172 KATNIP IFT80 IFT74 | Foot polydactyly |
| HP:0005918 | 0.00057619790463 | 0.4 | IFT56 IFT172 IFT27 IFT80 IFT74 KATNIP IFT57 IFT52 | Abnormal finger phalanx morphology |
| HP:0009136 | 0.000598196304452 | 0.25 | IFT27 IFT172 KATNIP IFT80 IFT74 | Duplication involving bones of the feet |
| GO:0031514 | 0.000703032821724 | 0.3 | IFT46 IFT88 IFT74 IFT81 IFT27 IFT52 | motile cilium |
| GO:0051179 | 0.00084737045524 | 0.85 | IFT25 CLUAP1 IFT46 IFT56 IFT88 IFT74 IFT80 TRAF3IP1 IFT27 IFT81 IFT22 IFT57 IFT70B IFT20 IFT70A IFT52 IFT172 | localization |
| HP:0000422 | 0.00109272281871 | 0.45 | IFT56 IFT172 IFT27 IFT74 IFT80 KATNIP IFT57 IFT52 IFT81 | Abnormal nasal bridge morphology |
| HP:0040069 | 0.00138306874876 | 0.4 | IFT56 IFT172 IFT27 IFT80 IFT74 TRAF3IP1 KATNIP IFT52 | Abnormal lower limb bone morphology |
| HP:0001830 | 0.00171688173161 | 0.2 | IFT27 IFT74 IFT172 IFT80 | Postaxial foot polydactyly |
| HP:0001161 | 0.00217464058727 | 0.25 | IFT27 IFT172 KATNIP IFT80 IFT74 | Hand polydactyly |
| HP:0010579 | 0.00262657708105 | 0.2 | TRAF3IP1 IFT80 IFT52 IFT172 | Cone-shaped epiphysis |
| HPA:0570761 | 0.00267655843934 | 0.55 | IFT56 IFT46 IFT70B IFT22 TFPI2 IFT74 IFT70A KATNIP IFT57 IFT52 IFT81 | testis; pachytene spermatocytes[>=Low] |
| HP:0011297 | 0.00269176743052 | 0.5 | IFT56 IFT172 IFT27 IFT74 IFT80 TRAF3IP1 KATNIP IFT57 IFT52 IFT81 | Abnormal digit morphology |
| HP:0012622 | 0.00286150588642 | 0.25 | IFT56 IFT27 IFT74 TRAF3IP1 IFT172 | Chronic kidney disease |
| HPA:0570762 | 0.00289432789169 | 0.5 | IFT56 IFT46 IFT70B IFT22 TFPI2 IFT74 IFT70A KATNIP IFT57 IFT81 | testis; pachytene spermatocytes[>=Medium] |
| REAC:R-HSA-5610787 | 0.00346416440233 | 0.2 | IFT88 IFT172 IFT52 IFT57 | Hedgehog 'off' state |
| WP:000000 | 0.00364341994752 | 0.9 | IFT25 CLUAP1 IFT46 IFT56 IFT88 IFT74 IFT172 IFT80 TRAF3IP1 IFT27 IFT81 IFT22 IFT57 IFT70B IFT20 IFT70A IFT52 KATNIP | WIKIPATHWAYS |
| GO:0035735 | 0.00382182132582 | 0.15 | IFT56 IFT81 IFT74 | intraciliary transport involved in cilium assembly |
| HP:0011927 | 0.00390698882612 | 0.35 | IFT172 IFT27 IFT80 IFT74 IFT81 IFT57 IFT52 | Short digit |
| HP:0005280 | 0.00422006427256 | 0.35 | IFT56 IFT172 IFT27 IFT80 IFT74 IFT81 IFT52 | Depressed nasal bridge |
| HP:0010322 | 0.00472022911318 | 0.2 | IFT27 IFT74 IFT172 IFT80 | Abnormal fifth toe morphology |
| HP:0000159 | 0.00549554755714 | 0.45 | IFT56 IFT172 IFT27 IFT74 IFT80 KATNIP IFT57 IFT52 IFT81 | Abnormal lip morphology |
| HP:0025691 | 0.00588649889473 | 0.15 | IFT27 IFT74 IFT172 | Impaired fasting glucose |
| HP:0000083 | 0.00638138897444 | 0.3 | IFT56 IFT172 IFT27 IFT74 IFT80 TRAF3IP1 | Renal insufficiency |
| HP:0005769 | 0.00664849722327 | 0.15 | IFT27 IFT74 IFT172 | Fifth finger distal phalanx clinodactyly |
| HP:0030010 | 0.00747303349126 | 0.15 | IFT27 IFT74 IFT172 | Hydrometrocolpos |
| HP:0009997 | 0.00785142225582 | 0.25 | IFT27 IFT172 KATNIP IFT80 IFT74 | Duplication of phalanx of hand |
| HP:0009142 | 0.00804077618576 | 0.25 | IFT27 IFT172 KATNIP IFT80 IFT74 | Duplication of bones involving the upper extremities |
| HP:0004275 | 0.00804077618576 | 0.25 | IFT27 IFT172 KATNIP IFT80 IFT74 | Duplication of hand bones |
| REAC:R-HSA-5358351 | 0.00829915832458 | 0.2 | IFT88 IFT172 IFT52 IFT57 | Signaling by Hedgehog |
| HP:0000426 | 0.00883434793511 | 0.25 | IFT57 IFT27 KATNIP IFT172 IFT74 | Prominent nasal bridge |
| HP:0040068 | 0.0092735028667 | 0.5 | IFT56 IFT172 IFT27 IFT74 IFT80 TRAF3IP1 KATNIP IFT57 IFT52 IFT81 | Abnormality of limb bone |
| HP:0002813 | 0.0092735028667 | 0.5 | IFT56 IFT172 IFT27 IFT74 IFT80 TRAF3IP1 KATNIP IFT57 IFT52 IFT81 | Abnormal limb bone morphology |
| HP:0008376 | 0.00931926013385 | 0.15 | IFT27 IFT74 IFT172 | Nasal dysarthria |
| HP:0008915 | 0.00931926013385 | 0.15 | IFT27 IFT74 IFT172 | Childhood-onset truncal obesity |
| HP:0001780 | 0.0123631512334 | 0.35 | IFT172 IFT27 IFT80 IFT74 KATNIP IFT57 IFT52 | Abnormal toe morphology |
| HP:0004225 | 0.0126170356344 | 0.15 | IFT27 IFT74 IFT172 | Abnormality of the distal phalanx of the 5th finger |
| HP:0000142 | 0.0132792968756 | 0.2 | IFT27 IFT74 IFT172 IFT80 | Abnormal vagina morphology |
| HP:0004322 | 0.0137385457468 | 0.45 | IFT56 IFT172 IFT27 IFT80 IFT74 TRAF3IP1 KATNIP IFT57 IFT52 | Short stature |
| HP:0000126 | 0.0137712224889 | 0.25 | IFT56 IFT27 IFT74 IFT172 IFT80 | Hydronephrosis |
| HP:0010747 | 0.013866630347 | 0.15 | IFT27 IFT74 IFT172 | Medial flaring of the eyebrow |
| HP:0000090 | 0.0151952932825 | 0.15 | TRAF3IP1 IFT80 IFT172 | Nephronophthisis |
| HP:0000774 | 0.0154003043858 | 0.2 | IFT52 IFT81 IFT172 IFT80 | Narrow chest |
| HP:0011844 | 0.0166967732658 | 0.5 | IFT56 IFT172 IFT27 IFT74 IFT80 TRAF3IP1 KATNIP IFT57 IFT52 IFT81 | Abnormal appendicular skeleton morphology |
| HP:0011314 | 0.0174304602707 | 0.35 | IFT56 IFT172 IFT80 TRAF3IP1 IFT81 IFT57 IFT52 | Abnormal long bone morphology |
| HP:0011026 | 0.0180991245507 | 0.15 | IFT27 IFT74 IFT172 | Aplasia/Hypoplasia of the vagina |
| HP:0005105 | 0.0184496122093 | 0.45 | IFT56 IFT172 IFT27 IFT74 IFT80 KATNIP IFT57 IFT52 IFT81 | Abnormal nasal morphology |
| HP:0010946 | 0.0194728382814 | 0.25 | IFT56 IFT27 IFT74 IFT172 IFT80 | Dilatation of the renal pelvis |
| HP:0002612 | 0.023105790357 | 0.15 | IFT56 IFT80 TRAF3IP1 | Congenital hepatic fibrosis |
| HP:0010944 | 0.0231585921307 | 0.25 | IFT56 IFT27 IFT74 IFT172 IFT80 | Abnormal renal pelvis morphology |
| GO:0035869 | 0.0238671820955 | 0.2 | IFT57 IFT20 IFT52 TRAF3IP1 | ciliary transition zone |
| HP:0010306 | 0.024957439701 | 0.15 | IFT80 IFT52 IFT172 | Short thorax |
| HP:0000002 | 0.0260811504012 | 0.45 | IFT56 IFT172 IFT27 IFT80 IFT74 TRAF3IP1 KATNIP IFT57 IFT52 | Abnormality of body height |
| HP:0003107 | 0.0281597343107 | 0.2 | IFT56 IFT27 IFT74 IFT172 | Abnormal circulating cholesterol concentration |
| HP:0005257 | 0.0299456268542 | 0.2 | IFT52 IFT81 IFT172 IFT80 | Thoracic hypoplasia |
| HP:0007703 | 0.0321522326489 | 0.25 | IFT88 IFT52 IFT80 TRAF3IP1 IFT172 | Abnormality of retinal pigmentation |
| WP:WP4830 | 0.0331677310052 | 0.1 | IFT25 IFT27 | GDNF RET signaling axis |
| HP:0003233 | 0.0333384967035 | 0.15 | IFT27 IFT74 IFT172 | Decreased HDL cholesterol concentration |
| HP:0004362 | 0.033765512311 | 0.2 | IFT27 KATNIP IFT172 IFT74 | Abnormal enteric ganglion morphology |
| HP:0002251 | 0.033765512311 | 0.2 | IFT27 KATNIP IFT172 IFT74 | Aganglionic megacolon |
| HP:0025028 | 0.0347738828416 | 0.2 | IFT27 KATNIP IFT172 IFT74 | Abnormal enteric nervous system morphology |
| HP:0012331 | 0.0347738828416 | 0.2 | IFT27 KATNIP IFT172 IFT74 | Abnormal autonomic nervous system morphology |
| HP:0000548 | 0.0356886548304 | 0.15 | IFT27 IFT74 IFT172 | Cone/cone-rod dystrophy |
| HP:0002099 | 0.0368567815798 | 0.2 | IFT56 IFT27 IFT74 IFT172 | Asthma |
| HP:0031888 | 0.0381452529772 | 0.15 | IFT27 IFT74 IFT172 | Abnormal HDL cholesterol concentration |
| HP:0002608 | 0.0407105178713 | 0.15 | IFT27 IFT74 IFT172 | Celiac disease |
| HP:0004213 | 0.04338666798 | 0.15 | IFT27 IFT74 IFT172 | Abnormal 5th finger phalanx morphology |
| HP:0001167 | 0.0471553449461 | 0.4 | IFT56 IFT172 IFT27 IFT80 IFT74 KATNIP IFT57 IFT52 | Abnormal finger morphology |
| GO:0016043 | 0.0475279163552 | 0.85 | IFT25 CLUAP1 IFT46 IFT56 IFT88 IFT74 IFT80 TRAF3IP1 IFT27 IFT81 IFT22 IFT57 IFT70B IFT20 IFT70A IFT52 IFT172 | cellular component organization |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap |
|---|---|---|---|---|
| IFT70A | IFT74 | 1.0 | 0.214 | |
| IFT70A | IFT27 | 1.0 | 0.124 | |
| IFT57 | IFT172 | 1.0 | 0.184 | |
| IFT70A | IFT56 | 1.0 | 0.16 | |
| IFT70A | IFT81 | 1.0 | 0.268 | |
| IFT70A | IFT52 | 1.0 | 0.186 |
structurally_consistent (dimer)
|
| IFT80 | IFT27 | 1.0 | ||
| IFT74 | IFT70B | 1.0 |
structurally_consistent (dimer)
|
|
| IFT88 | IFT70B | 1.0 |
structurally_consistent (dimer)
|
|
| IFT57 | IFT80 | 1.0 | ||
| IFT70A | IFT172 | 1.0 | 0.266 | |
| IFT57 | IFT20 | 1.0 | 0.156 | |
| IFT57 | IFT46 | 1.0 | 0.148 | |
| IFT70A | IFT22 | 1.0 | 0.274 | |
| IFT70A | IFT46 | 1.0 | 0.182 |
structurally_consistent (dimer)
|
| IFT70A | CLUAP1 | 1.0 | ||
| IFT57 | TRAF3IP1 | 1.0 | 0.284 | |
| IFT80 | IFT70A | 1.0 | ||
| IFT70A | TRAF3IP1 | 1.0 | 0.22 | |
| IFT57 | CLUAP1 | 1.0 | ||
| IFT70A | IFT88 | 1.0 | 0.182 | |
| IFT27 | IFT56 | 1.0 | 0.066 | |
| IFT27 | IFT46 | 1.0 | 0.242 | |
| IFT52 | IFT70B | 1.0 |
mutually_exclusive (Q13099)
structurally_consistent (dimer) |
|
| IFT57 | IFT70A | 1.0 | 0.282 | |
| IFT81 | IFT70B | 1.0 | ||
| IFT52 | IFT22 | 1.0 | 0.174 | |
| IFT20 | IFT70B | 1.0 | ||
| IFT22 | TRAF3IP1 | 1.0 | 0.226 | |
| IFT80 | IFT70B | 1.0 | ||
| IFT172 | IFT22 | 1.0 | 0.19 | |
| IFT56 | IFT70B | 1.0 | ||
| IFT56 | IFT22 | 1.0 | 0.304 | |
| IFT80 | IFT22 | 1.0 | ||
| IFT46 | IFT22 | 1.0 | 0.194 | |
| IFT46 | IFT70B | 1.0 | ||
| IFT81 | IFT74 | 1.0 | 0.336 | |
| IFT27 | IFT52 | 1.0 | 0.06 | |
| IFT88 | IFT22 | 1.0 | 0.276 | |
| IFT27 | IFT172 | 1.0 | 0.026 | |
| IFT27 | IFT88 | 1.0 | 0.098 | |
| IFT81 | IFT22 | 1.0 | 0.246 | |
| IFT27 | CLUAP1 | 1.0 | ||
| IFT27 | IFT22 | 1.0 | 0.064 | |
| IFT57 | IFT22 | 1.0 | 0.238 | |
| IFT22 | IFT74 | 1.0 | 0.158 | |
| IFT172 | IFT70B | 1.0 | ||
| IFT22 | CLUAP1 | 1.0 | ||
| IFT27 | IFT81 | 0.999 | 0.092 | |
| IFT22 | IFT70B | 0.999 | ||
| IFT80 | IFT74 | 0.999 |
mutually_exclusive (Q8IY31)
|
|
| IFT70A | IFT20 | 0.999 | 0.2 | |
| IFT20 | IFT22 | 0.999 | 0.104 | |
| IFT57 | IFT88 | 0.999 | 0.182 |
structurally_consistent (dimer)
|
| IFT46 | IFT88 | 0.999 | 0.218 | |
| IFT80 | IFT88 | 0.999 | ||
| IFT57 | IFT27 | 0.999 | 0.09 | |
| IFT27 | TRAF3IP1 | 0.999 | 0.13 | |
| IFT27 | IFT70B | 0.999 | ||
| IFT70A | IFT25 | 0.999 | 0.094 | |
| CLUAP1 | IFT70B | 0.999 |
structurally_consistent (dimer)
|
|
| TRAF3IP1 | IFT70B | 0.999 | ||
| IFT52 | IFT46 | 0.999 | 0.196 |
mutually_exclusive (Q86WT1)
|
| IFT57 | IFT74 | 0.999 | 0.204 | |
| IFT46 | TRAF3IP1 | 0.999 | 0.104 | |
| IFT27 | IFT25 | 0.999 | 0.016 | |
| IFT57 | IFT52 | 0.999 | 0.23 | |
| IFT57 | IFT56 | 0.999 | 0.234 | |
| IFT80 | IFT46 | 0.999 | ||
| IFT46 | IFT81 | 0.999 | 0.286 | |
| IFT46 | IFT20 | 0.999 | 0.102 | |
| IFT70A | IFT70B | 0.999 | ||
| IFT27 | IFT20 | 0.999 | 0.106 | |
| IFT25 | IFT70B | 0.999 |
structurally_consistent (Q13099)
|
|
| IFT20 | TRAF3IP1 | 0.999 | 0.152 | |
| IFT27 | IFT74 | 0.999 | 0.028 | |
| IFT172 | IFT46 | 0.999 | 0.138 | |
| IFT46 | CLUAP1 | 0.999 | ||
| IFT80 | IFT20 | 0.998 |
structurally_consistent (dimer)
|
|
| IFT172 | IFT20 | 0.998 | 0.186 | |
| IFT80 | IFT52 | 0.998 | ||
| IFT88 | CLUAP1 | 0.998 | ||
| IFT88 | IFT74 | 0.998 | 0.184 | |
| IFT57 | IFT70B | 0.998 |
structurally_consistent (Q13099)
|
|
| IFT52 | CLUAP1 | 0.998 |
mutually_exclusive (Q8N4P2)
|
|
| IFT80 | IFT172 | 0.998 | ||
| IFT172 | CLUAP1 | 0.998 | ||
| IFT172 | IFT88 | 0.998 | 0.282 | |
| IFT80 | CLUAP1 | 0.998 |
structurally_consistent (Q8IY31)
|
|
| CLUAP1 | IFT74 | 0.998 | ||
| IFT46 | IFT56 | 0.998 | 0.186 | |
| IFT88 | TRAF3IP1 | 0.998 | 0.302 | |
| IFT80 | TRAF3IP1 | 0.998 | ||
| CLUAP1 | TRAF3IP1 | 0.998 | ||
| IFT172 | IFT52 | 0.998 | 0.24 | |
| IFT81 | TRAF3IP1 | 0.998 | 0.182 | |
| IFT57 | IFT81 | 0.997 | 0.172 | |
| IFT46 | IFT74 | 0.997 | 0.188 | |
| IFT20 | IFT88 | 0.997 | 0.084 | |
| IFT172 | TRAF3IP1 | 0.997 | 0.226 | |
| IFT88 | IFT56 | 0.997 | 0.128 | |
| IFT80 | IFT56 | 0.997 | ||
| IFT52 | IFT56 | 0.997 | 0.244 | |
| IFT20 | CLUAP1 | 0.997 |
structurally_consistent (dimer)
|
|
| IFT25 | IFT46 | 0.997 | 0.06 | |
| IFT52 | TRAF3IP1 | 0.997 | 0.162 | |
| IFT52 | IFT81 | 0.997 | 0.232 |
structurally_consistent (Q13099)
|
| IFT52 | IFT88 | 0.997 | 0.174 |
mutually_exclusive (Q8N4P2)
structurally_consistent (dimer) |
| IFT81 | CLUAP1 | 0.997 | ||
| IFT25 | IFT22 | 0.997 | 0.056 | |
| IFT80 | IFT81 | 0.996 | ||
| IFT56 | CLUAP1 | 0.996 | ||
| IFT56 | IFT81 | 0.996 | 0.302 | |
| IFT52 | IFT74 | 0.996 | 0.212 |
mutually_exclusive (Q8N4P2)
|
| IFT172 | IFT74 | 0.996 | 0.128 | |
| IFT57 | IFT25 | 0.996 | 0.14 | |
| IFT172 | IFT81 | 0.995 | 0.26 | |
| IFT74 | TRAF3IP1 | 0.995 | 0.256 | |
| IFT52 | IFT20 | 0.994 | 0.224 | |
| IFT88 | IFT81 | 0.994 | 0.216 |
structurally_consistent (dimer)
|
| IFT20 | IFT81 | 0.992 | 0.13 | |
| IFT25 | IFT81 | 0.992 | 0.048 |
structurally_consistent (Q13099)
|
| IFT25 | IFT74 | 0.99 | 0.088 | |
| IFT52 | IFT25 | 0.989 | 0.086 |
mutually_exclusive (Q13099)
|
| IFT56 | TRAF3IP1 | 0.987 | 0.23 | |
| IFT20 | IFT56 | 0.986 | 0.086 | |
| IFT56 | IFT74 | 0.973 | 0.16 | |
| IFT20 | IFT74 | 0.959 | 0.288 |
structurally_consistent (dimer)
|
| IFT57 | KATNIP | 0.948 | 0.196 | |
| ZC2HC1C | IFT57 | 0.925 | ||
| IFT22 | TFPI2 | 0.924 | 0.058 | |
| ZC2HC1C | IFT46 | 0.918 | ||
| IFT52 | TFPI2 | 0.912 | 0.058 | |
| IFT80 | IFT25 | 0.911 | ||
| IFT46 | TFPI2 | 0.91 | 0.032 | |
| IFT25 | TRAF3IP1 | 0.908 | 0.048 | |
| IFT25 | IFT20 | 0.907 | 0.072 | |
| IFT25 | CLUAP1 | 0.873 | ||
| IFT25 | IFT88 | 0.87 | 0.232 |
structurally_consistent (dimer)
|
| IFT172 | TFPI2 | 0.844 | 0.096 | |
| TRAF3IP1 | TFPI2 | 0.836 | 0.086 | |
| IFT88 | TFPI2 | 0.835 | 0.092 | |
| IFT172 | IFT25 | 0.817 | 0.038 | |
| IFT81 | TFPI2 | 0.813 | 0.096 | |
| CLUAP1 | KATNIP | 0.811 | ||
| IFT88 | KATNIP | 0.811 | 0.158 | |
| TRAF3IP1 | KATNIP | 0.811 | 0.166 | |
| IFT20 | KATNIP | 0.811 | 0.186 | |
| ZC2HC1C | IFT22 | 0.81 | ||
| IFT172 | IFT56 | 0.801 | 0.174 | |
| ZC2HC1C | IFT52 | 0.784 | ||
| IFT27 | TFPI2 | 0.776 | 0.006 | |
| IFT74 | TFPI2 | 0.771 | 0.096 | |
| IFT57 | TFPI2 | 0.754 | 0.088 | |
| IFT70A | TFPI2 | 0.744 | 0.066 | |
| ZC2HC1C | IFT172 | 0.736 | ||
| IFT25 | IFT56 | 0.58 | 0.04 | |
| ZC2HC1C | IFT25 | 0.479 | ||
| ZC2HC1C | IFT74 | 0.185 | ||
| IFT56 | TFPI2 | 0.168 | 0.072 | |
| CLUAP1 | TFPI2 | 0.167 | ||
| ZC2HC1C | IFT88 | 0.157 | ||
| ZC2HC1C | IFT70A | 0.15 | ||
| ZC2HC1C | IFT81 | 0.131 | ||
| ZC2HC1C | IFT56 | 0.096 | ||
| IFT27 | KATNIP | 0.087 | 0.102 | |
| IFT25 | KATNIP | 0.087 | 0.07 | |
| IFT52 | KATNIP | 0.087 | 0.18 | |
| IFT56 | KATNIP | 0.087 | 0.139 | |
| IFT74 | KATNIP | 0.087 | 0.174 | |
| IFT22 | KATNIP | 0.087 | 0.1 | |
| IFT46 | KATNIP | 0.068 | 0.126 | |
| IFT81 | KATNIP | 0.061 | 0.144 | |
| IFT172 | KATNIP | 0.051 | 0.202 | |
| IFT80 | KATNIP | 0.051 | ||
| IFT70A | KATNIP | 0.051 | 0.114 | |
| IFT25 | TFPI2 | 0.038 | 0.016 |
Related Complexes
| Genename | Complexes |
|---|---|
| ZC2HC1C | huMAP3_00896.1 huMAP3_11423.1 huMAP3_13176.1 huMAP3_13817.1 |
| IFT25 | huMAP3_05411.1 huMAP3_13817.1 |
| KATNIP | huMAP3_13817.1 |
| IFT88 | huMAP3_05411.1 huMAP3_13817.1 |
| IFT81 | huMAP3_05411.1 huMAP3_13817.1 |
| IFT74 | huMAP3_05411.1 huMAP3_11968.1 huMAP3_13817.1 |
| IFT80 | huMAP3_05411.1 huMAP3_13817.1 |
| IFT46 | huMAP3_05411.1 huMAP3_13817.1 |
| IFT56 | huMAP3_05411.1 huMAP3_13817.1 |
| IFT22 | huMAP3_05411.1 huMAP3_11423.1 huMAP3_13817.1 |
| CLUAP1 | huMAP3_05411.1 huMAP3_13817.1 |
| TFPI2 | huMAP3_13817.1 |
| IFT70B | huMAP3_05411.1 huMAP3_13817.1 |
| IFT70A | huMAP3_05411.1 huMAP3_13817.1 |
| IFT57 | huMAP3_05082.1 huMAP3_05411.1 huMAP3_09493.1 huMAP3_13817.1 |
| IFT172 | huMAP3_05411.1 huMAP3_13817.1 |
| TRAF3IP1 | huMAP3_05411.1 huMAP3_13817.1 |
| IFT52 | huMAP3_05411.1 huMAP3_13817.1 |
| IFT27 | huMAP3_05411.1 huMAP3_13817.1 |
| IFT20 | huMAP3_05411.1 huMAP3_13817.1 |