hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_13828.1
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| DOC2A | Double C2-like domain-containing protein alpha (Doc2) (Doc2-alpha) | 5 | UniProt NCBI |
| KCTD21 | BTB/POZ domain-containing protein KCTD21 (KCASH2 protein) (Potassium channel tetramerization domain-containing protein 21) | 5 | UniProt NCBI |
| UBASH3B | Ubiquitin-associated and SH3 domain-containing protein B (EC 3.1.3.48) (Cbl-interacting protein p70) (Suppressor of T-cell receptor signaling 1) (STS-1) (T-cell ubiquitin ligand 2) (TULA-2) (Tyrosine-protein phosphatase STS1/TULA2) | 5 | UniProt NCBI |
| FAM209A | Protein FAM209A | 5 | UniProt NCBI |
| MSRA | Mitochondrial peptide methionine sulfoxide reductase (EC 1.8.4.11) (Peptide-methionine (S)-S-oxide reductase) (Peptide Met(O) reductase) (Protein-methionine-S-oxide reductase) (PMSR) | 5 | UniProt NCBI |
| RPH3A | Rabphilin-3A (Exophilin-1) | 5 | UniProt NCBI |
| DOC2B | Double C2-like domain-containing protein beta (Doc2-beta) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0061669 | 6.72425931667e-05 | 0.428571428571 | RPH3A DOC2A DOC2B | spontaneous neurotransmitter secretion |
| GO:0098814 | 0.00040312426486 | 0.428571428571 | RPH3A DOC2A DOC2B | spontaneous synaptic transmission |
| GO:0017158 | 0.00516068999797 | 0.428571428571 | RPH3A DOC2A DOC2B | regulation of calcium ion-dependent exocytosis |
| GO:0098850 | 0.00983221512175 | 0.285714285714 | RPH3A DOC2A | extrinsic component of synaptic vesicle membrane |
| GO:0017156 | 0.0218744047191 | 0.428571428571 | RPH3A DOC2A DOC2B | calcium-ion regulated exocytosis |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| DOC2A | DOC2B | 0.999 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| DOC2A | KCTD21 | 0.998 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| RPH3A | DOC2B | 0.994 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| DOC2A | UBASH3B | 0.993 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| MSRA | UBASH3B | 0.987 | 0.058 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only |
| DOC2B | UBASH3B | 0.932 | bioplex_WMM bioplex3_WMM WMM_only | |
| UBASH3B | FAM209A | 0.931 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| DOC2B | KCTD21 | 0.921 | bioplex_WMM bioplex3_WMM WMM_only | |
| UBASH3B | KCTD21 | 0.886 | 0.096 | bioplex_WMM bioplex3_WMM WMM_only |
| DOC2A | RPH3A | 0.078 | bioplex3_WMM WMM_only |
Related Complexes