hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_13829.1
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| TGFB2 | Transforming growth factor beta-2 proprotein (Cetermin) (Glioblastoma-derived T-cell suppressor factor) (G-TSF) [Cleaved into: Latency-associated peptide (LAP); Transforming growth factor beta-2 (TGF-beta-2)] | 5 | UniProt NCBI |
| FAM118A | Protein FAM118A | 5 | UniProt NCBI |
| TGFB1 | Transforming growth factor beta-1 proprotein [Cleaved into: Latency-associated peptide (LAP); Transforming growth factor beta-1 (TGF-beta-1)] | 5 | UniProt NCBI |
| TGFB3 | Transforming growth factor beta-3 proprotein [Cleaved into: Latency-associated peptide (LAP); Transforming growth factor beta-3 (TGF-beta-3)] | 5 | UniProt NCBI |
| ITGB8 | Integrin beta-8 | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:05410 | 0.00216826178203 | 0.666666666667 | TGFB2 ITGB8 | Hypertrophic cardiomyopathy |
| KEGG:05414 | 0.00216826178203 | 0.666666666667 | TGFB2 ITGB8 | Dilated cardiomyopathy |
| REAC:R-HSA-2129379 | 0.00276488364952 | 0.666666666667 | TGFB2 ITGB8 | Molecules associated with elastic fibres |
| REAC:R-HSA-1566948 | 0.00428896488724 | 0.666666666667 | TGFB2 ITGB8 | Elastic fibre formation |
| REAC:R-HSA-2173789 | 0.005581186855 | 0.666666666667 | TGFB2 ITGB8 | TGF-beta receptor signaling activates SMADs |
| REAC:R-HSA-170834 | 0.0254089329805 | 0.666666666667 | TGFB2 ITGB8 | Signaling by TGF-beta Receptor Complex |
| REAC:R-HSA-9006936 | 0.0392065258044 | 0.666666666667 | TGFB2 ITGB8 | Signaling by TGFB family members |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| TGFB1 | ITGB8 | 0.987 | 0.28253968254 | bioplex3_WMM bioplex3_HCT116 WMM_only |
| TGFB3 | TGFB1 | 0.975 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| TGFB2 | TGFB1 | 0.974 | 0.482551724138 | bioplex3_WMM bioplex3_HCT116 WMM_only |
| FAM118A | ITGB8 | 0.89 | 0.082 | bioplex3_WMM WMM_only |
| TGFB2 | ITGB8 | 0.89 | 0.105333333333 | bioplex3_WMM WMM_only |
| TGFB3 | ITGB8 | 0.214 | bioplex3_WMM WMM_only | |
| TGFB3 | TGFB2 | 0.214 | bioplex3_WMM WMM_only |
Related Complexes