hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_13835.1
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| CREB3L3 | Cyclic AMP-responsive element-binding protein 3-like protein 3 (cAMP-responsive element-binding protein 3-like protein 3) (Transcription factor CREB-H) [Cleaved into: Processed cyclic AMP-responsive element-binding protein 3-like protein 3] | 5 | UniProt NCBI |
| CREB3L4 | Cyclic AMP-responsive element-binding protein 3-like protein 4 (cAMP-responsive element-binding protein 3-like protein 4) (Androgen-induced basic leucine zipper protein) (AIbZIP) (Attaching to CRE-like 1) (ATCE1) (Cyclic AMP-responsive element-binding protein 4) (CREB-4) (cAMP-responsive element-binding protein 4) (Transcript induced in spermiogenesis protein 40) (Tisp40) (hJAL) [Cleaved into: Processed cyclic AMP-responsive element-binding protein 3-like protein 4] | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-8874211 | 3.58839967947e-05 | 1.0 | CREB3L4 CREB3L3 | CREB3 factors activate genes |
| WP:WP5272 | 7.2783930122e-05 | 1.0 | CREB3L4 CREB3L3 | LDL influence on CD14 and TLR4 |
| KEGG:04962 | 0.000126804361689 | 1.0 | CREB3L4 CREB3L3 | Vasopressin-regulated water reabsorption |
| KEGG:05030 | 0.000133307149468 | 1.0 | CREB3L4 CREB3L3 | Cocaine addiction |
| KEGG:04927 | 0.000139972506942 | 1.0 | CREB3L4 CREB3L3 | Cortisol synthesis and secretion |
| WP:WP4756 | 0.000238782367243 | 1.0 | CREB3L4 CREB3L3 | Renin angiotensin aldosterone system RAAS |
| KEGG:05031 | 0.00025946123238 | 1.0 | CREB3L4 CREB3L3 | Amphetamine addiction |
| KEGG:04918 | 0.000287748359218 | 1.0 | CREB3L4 CREB3L3 | Thyroid hormone synthesis |
| WP:WP5085 | 0.000331996874241 | 1.0 | CREB3L4 CREB3L3 | Vasopressin regulated water reabsorption |
| KEGG:04911 | 0.000338144964505 | 1.0 | CREB3L4 CREB3L3 | Insulin secretion |
| KEGG:04925 | 0.000439100744773 | 1.0 | CREB3L4 CREB3L3 | Aldosterone synthesis and secretion |
| KEGG:04211 | 0.000526725810094 | 1.0 | CREB3L4 CREB3L3 | Longevity regulating pathway |
| KEGG:04916 | 0.000553224670293 | 1.0 | CREB3L4 CREB3L3 | Melanogenesis |
| KEGG:04928 | 0.000553224670293 | 1.0 | CREB3L4 CREB3L3 | Parathyroid hormone synthesis, secretion and action |
| KEGG:04725 | 0.000636622923558 | 1.0 | CREB3L4 CREB3L3 | Cholinergic synapse |
| KEGG:05215 | 0.000651091626366 | 1.0 | CREB3L4 CREB3L3 | Prostate cancer |
| KEGG:04915 | 0.000680516741066 | 1.0 | CREB3L4 CREB3L3 | Estrogen signaling pathway |
| KEGG:04922 | 0.000680516741066 | 1.0 | CREB3L4 CREB3L3 | Glucagon signaling pathway |
| KEGG:04668 | 0.000725873685824 | 1.0 | CREB3L4 CREB3L3 | TNF signaling pathway |
| KEGG:04931 | 0.000772693757832 | 1.0 | CREB3L4 CREB3L3 | Insulin resistance |
| KEGG:04935 | 0.000804719987643 | 1.0 | CREB3L4 CREB3L3 | Growth hormone synthesis, secretion and action |
| WP:WP45 | 0.000858084228807 | 1.0 | CREB3L4 CREB3L3 | G1 to S cell cycle control |
| KEGG:04926 | 0.000939327694667 | 1.0 | CREB3L4 CREB3L3 | Relaxin signaling pathway |
| KEGG:04728 | 0.00095688522167 | 1.0 | CREB3L4 CREB3L3 | Dopaminergic synapse |
| KEGG:04152 | 0.00102874102663 | 1.0 | CREB3L4 CREB3L3 | AMPK signaling pathway |
| KEGG:04261 | 0.0011414018249 | 1.0 | CREB3L4 CREB3L3 | Adrenergic signaling in cardiomyocytes |
| KEGG:04022 | 0.00125991513217 | 1.0 | CREB3L4 CREB3L3 | cGMP-PKG signaling pathway |
| KEGG:04934 | 0.00125991513217 | 1.0 | CREB3L4 CREB3L3 | Cushing syndrome |
| WP:WP4321 | 0.00174298358976 | 1.0 | CREB3L4 CREB3L3 | Thermogenesis |
| KEGG:05161 | 0.00176843313648 | 1.0 | CREB3L4 CREB3L3 | Hepatitis B |
| KEGG:05034 | 0.00179249345126 | 1.0 | CREB3L4 CREB3L3 | Alcoholism |
| KEGG:04024 | 0.00201635192055 | 1.0 | CREB3L4 CREB3L3 | cAMP signaling pathway |
| KEGG:05207 | 0.00214640767613 | 1.0 | CREB3L4 CREB3L3 | Chemical carcinogenesis - receptor activation |
| KEGG:05203 | 0.00279701159341 | 1.0 | CREB3L4 CREB3L3 | Viral carcinogenesis |
| KEGG:05163 | 0.00298087791786 | 1.0 | CREB3L4 CREB3L3 | Human cytomegalovirus infection |
| KEGG:05166 | 0.00317059675131 | 1.0 | CREB3L4 CREB3L3 | Human T-cell leukemia virus 1 infection |
| KEGG:04714 | 0.00339933231144 | 1.0 | CREB3L4 CREB3L3 | Thermogenesis |
| WP:WP4666 | 0.00396523446209 | 1.0 | CREB3L4 CREB3L3 | Hepatitis B infection |
| KEGG:05020 | 0.00485920816781 | 1.0 | CREB3L4 CREB3L3 | Prion disease |
| KEGG:05016 | 0.00594761227231 | 1.0 | CREB3L4 CREB3L3 | Huntington disease |
| REAC:R-HSA-381119 | 0.00595674346792 | 1.0 | CREB3L4 CREB3L3 | Unfolded Protein Response (UPR) |
| KEGG:04151 | 0.00662552789826 | 1.0 | CREB3L4 CREB3L3 | PI3K-Akt signaling pathway |
| KEGG:05165 | 0.00700203931066 | 1.0 | CREB3L4 CREB3L3 | Human papillomavirus infection |
| WP:WP3932 | 0.0130364105952 | 1.0 | CREB3L4 CREB3L3 | Focal adhesion PI3K Akt mTOR signaling pathway |
| WP:WP4172 | 0.015571930313 | 1.0 | CREB3L4 CREB3L3 | PI3K Akt signaling pathway |
| HPA:0480892 | 0.0245263757673 | 1.0 | CREB3L4 CREB3L3 | small intestine; goblet cells[>=Medium] |
| HPA:0150891 | 0.0342743388315 | 1.0 | CREB3L4 CREB3L3 | duodenum; goblet cells[>=Low] |
| HPA:0480891 | 0.0350915837902 | 1.0 | CREB3L4 CREB3L3 | small intestine; goblet cells[>=Low] |
| HPA:0151302 | 0.0401972584807 | 1.0 | CREB3L4 CREB3L3 | duodenum; enterocytes[>=Medium] |
| HPA:0481302 | 0.0408598407336 | 1.0 | CREB3L4 CREB3L3 | small intestine; enterocytes[>=Medium] |
| HPA:0131291 | 0.0419761804968 | 1.0 | CREB3L4 CREB3L3 | colon; endocrine cells[>=Low] |
| HPA:0151292 | 0.0440235054965 | 1.0 | CREB3L4 CREB3L3 | duodenum; endocrine cells[>=Medium] |
| HPA:0481292 | 0.044253995054 | 1.0 | CREB3L4 CREB3L3 | small intestine; endocrine cells[>=Medium] |
| HPA:0481291 | 0.0499662845592 | 1.0 | CREB3L4 CREB3L3 | small intestine; endocrine cells[>=Low] |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| CREB3L3 | CREB3L4 | 0.997 | bioplex3_WMM bioplex3_HCT116 WMM_only |
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