hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_13842.1
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| FAM83F | Protein FAM83F | 3 | UniProt NCBI |
| SPIDR | DNA repair-scaffolding protein (Scaffolding protein involved in DNA repair) | 5 | UniProt NCBI |
| ZSWIM7 | Zinc finger SWIM domain-containing protein 7 (SWIM domain-containing and Srs2-interacting protein 1 homolog) (SWIM-type zinc finger domain-containing protein 7) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HP:0005625 | 0.00115089028102 | 0.666666666667 | SPIDR ZSWIM7 | Osteoporosis of vertebrae |
| HP:0040161 | 0.00132788970801 | 0.666666666667 | SPIDR ZSWIM7 | Localized osteoporosis |
| HP:0011969 | 0.00265505202111 | 0.666666666667 | SPIDR ZSWIM7 | Elevated circulating luteinizing hormone level |
| HP:0010464 | 0.00292042386749 | 0.666666666667 | SPIDR ZSWIM7 | Streak ovary |
| HP:0000133 | 0.00513122551172 | 0.666666666667 | SPIDR ZSWIM7 | Gonadal dysgenesis |
| HP:0008232 | 0.00513122551172 | 0.666666666667 | SPIDR ZSWIM7 | Elevated circulating follicle stimulating hormone level |
| HP:0002225 | 0.00795970060154 | 0.666666666667 | SPIDR ZSWIM7 | Sparse pubic hair |
| HP:0100133 | 0.00888120343534 | 0.666666666667 | SPIDR ZSWIM7 | Abnormality of the pubic hair |
| HP:0008214 | 0.00888120343534 | 0.666666666667 | SPIDR ZSWIM7 | Decreased serum estradiol |
| HP:0025133 | 0.0130706759587 | 0.666666666667 | SPIDR ZSWIM7 | Abnormal serum estradiol |
| HP:0025132 | 0.0130706759587 | 0.666666666667 | SPIDR ZSWIM7 | Abnormal circulating estrogen level |
| HP:0030345 | 0.0136509708315 | 0.666666666667 | SPIDR ZSWIM7 | Abnormal circulating luteinizing hormone concentration |
| HP:0030346 | 0.0180650213362 | 0.666666666667 | SPIDR ZSWIM7 | Abnormal circulating follicle-stimulating hormone concentration |
| HP:0009888 | 0.0180650213362 | 0.666666666667 | SPIDR ZSWIM7 | Abnormality of secondary sexual hair |
| HP:0000837 | 0.0194392651505 | 0.666666666667 | SPIDR ZSWIM7 | Increased circulating gonadotropin level |
| HP:0000869 | 0.0194392651505 | 0.666666666667 | SPIDR ZSWIM7 | Secondary amenorrhea |
| HP:0010311 | 0.0201452261528 | 0.666666666667 | SPIDR ZSWIM7 | Aplasia/Hypoplasia of the breasts |
| HP:0008209 | 0.0208637442425 | 0.666666666667 | SPIDR ZSWIM7 | Premature ovarian insufficiency |
| HP:0008684 | 0.0270637362845 | 0.666666666667 | SPIDR ZSWIM7 | Aplasia/hypoplasia of the uterus |
| HP:0002206 | 0.0287391839378 | 0.666666666667 | SPIDR ZSWIM7 | Pulmonary fibrosis |
| HP:0008724 | 0.0295957156854 | 0.666666666667 | SPIDR ZSWIM7 | Hypoplasia of the ovary |
| HP:0010462 | 0.0313463863633 | 0.666666666667 | SPIDR ZSWIM7 | Aplasia/Hypoplasia of the ovary |
| HP:0031066 | 0.037868427304 | 0.666666666667 | SPIDR ZSWIM7 | Abnormal ovarian physiology |
| HP:0030338 | 0.0429026841472 | 0.666666666667 | SPIDR ZSWIM7 | Abnormal circulating gonadotropin concentration |
| HP:0033799 | 0.0460733968082 | 0.666666666667 | SPIDR ZSWIM7 | Abnormal circulating sex hormone concentration |
| HP:0010514 | 0.047155317063 | 0.666666666667 | SPIDR ZSWIM7 | Hyperpituitarism |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| SPIDR | FAM83F | 0.995 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| SPIDR | ZSWIM7 | 0.984 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes