hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_13843.1
Complex Portal: CPX-17714
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| MYPN | Myopalladin (145 kDa sarcomeric protein) | 5 | UniProt NCBI |
| TRAF5 | TNF receptor-associated factor 5 (RING finger protein 84) | 5 | UniProt NCBI |
| HOMER1 | Homer protein homolog 1 (Homer-1) | 5 | UniProt NCBI |
| HOMER2 | Homer protein homolog 2 (Homer-2) (Cupidin) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:04724 | 0.00806816574582 | 0.5 | HOMER1 HOMER2 | Glutamatergic synapse |
| WP:WP5417 | 0.0092628309276 | 0.5 | HOMER1 HOMER2 | Cell lineage map for neuronal differentiation |
| REAC:R-HSA-6794361 | 0.0105688559686 | 0.5 | HOMER1 HOMER2 | Neurexins and neuroligins |
| KEGG:04068 | 0.0157117070582 | 0.5 | HOMER1 HOMER2 | FoxO signaling pathway |
| REAC:R-HSA-6794362 | 0.0246065982605 | 0.5 | HOMER1 HOMER2 | Protein-protein interactions at synapses |
| GO:0007216 | 0.042122686785 | 0.5 | HOMER1 HOMER2 | G protein-coupled glutamate receptor signaling pathway |
| GO:2001256 | 0.042122686785 | 0.5 | HOMER1 HOMER2 | regulation of store-operated calcium entry |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| HOMER2 | HOMER1 | 0.998 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| TRAF5 | HOMER1 | 0.973 | 0.122 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| HOMER1 | MYPN | 0.923 | 0.0500418848168 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| HOMER2 | MYPN | 0.903 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| TRAF5 | HOMER2 | 0.215 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes