hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_13861.1
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| GGT1 | Glutathione hydrolase 1 proenzyme (EC 3.4.19.13) (Gamma-glutamyltransferase 1) (Gamma-glutamyltranspeptidase 1) (GGT 1) (EC 2.3.2.2) (Leukotriene-C4 hydrolase) (EC 3.4.19.14) (CD antigen CD224) [Cleaved into: Glutathione hydrolase 1 heavy chain; Glutathione hydrolase 1 light chain] | 5 | UniProt NCBI |
| SOD3 | Extracellular superoxide dismutase [Cu-Zn] (EC-SOD) (EC 1.15.1.1) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP15 | 0.000969601127591 | 1.0 | GGT1 SOD3 | Selenium micronutrient network |
| WP:WP2884 | 0.00264575970549 | 1.0 | GGT1 SOD3 | NRF2 pathway |
| WP:WP2882 | 0.0133543614478 | 1.0 | GGT1 SOD3 | Nuclear receptors meta pathway |
| KEGG:00430 | 0.0237506195141 | 0.5 | GGT1 | Taurine and hypotaurine metabolism |
| REAC:R-HSA-5579022 | 0.0249718442457 | 0.5 | GGT1 | Defective GGT1 causes GLUTH |
| REAC:R-HSA-9035968 | 0.0249718442457 | 0.5 | GGT1 | Defective GGT1 in aflatoxin detoxification causes GLUTH |
| WP:WP4518 | 0.0373151717536 | 0.5 | GGT1 | Gamma glutamyl cycle for the biosynthesis and degradation of glutathione including diseases |
| HP:0034445 | 0.0499436884913 | 0.5 | GGT1 | Reduced gamma-glutamyltransferase level |
| HP:0034586 | 0.0499436884913 | 0.5 | GGT1 | Glutathionuria |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| SOD3 | GGT1 | 0.902 | 0.106 | bioplex3_WMM WMM_only |
Related Complexes
| Genename | Complexes |
|---|---|
| GGT1 | huMAP3_12066.1 huMAP3_13861.1 |
| SOD3 | huMAP3_02164.1 huMAP3_07757.1 huMAP3_08022.1 huMAP3_09567.1 huMAP3_13861.1 |