hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_13884.1
Complex Portal: CPX-22831
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| PDSS1 | All trans-polyprenyl-diphosphate synthase PDSS1 (All-trans-decaprenyl-diphosphate synthase subunit 1) (EC 2.5.1.91) (Decaprenyl pyrophosphate synthase subunit 1) (Decaprenyl-diphosphate synthase subunit 1) (Solanesyl-diphosphate synthase subunit 1) (Trans-prenyltransferase 1) (TPT 1) | 5 | UniProt NCBI |
| ACAD9 | Complex I assembly factor ACAD9, mitochondrial (Acyl-CoA dehydrogenase family member 9) (ACAD-9) (EC 1.3.8.-) | 5 | UniProt NCBI |
| MCCD1 | Mitochondrial coiled-coil domain protein 1 | 5 | UniProt NCBI |
| MTRF1L | Peptide chain release factor 1-like, mitochondrial (Mitochondrial translational release factor 1-like) (mtRF1a) | 5 | UniProt NCBI |
| PDSS2 | All trans-polyprenyl-diphosphate synthase PDSS2 (All-trans-decaprenyl-diphosphate synthase subunit 2) (EC 2.5.1.91) (Candidate tumor suppressor protein) (Decaprenyl pyrophosphate synthase subunit 2) (Decaprenyl-diphosphate synthase subunit 2) (Solanesyl-diphosphate synthase subunit 2) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-2142789 | 0.000319009353903 | 0.4 | PDSS2 PDSS1 | Ubiquinol biosynthesis |
| WP:WP5037 | 0.0003876755558 | 0.4 | PDSS2 PDSS1 | Riboflavin and CoQ disorders |
| KEGG:00900 | 0.00104717092459 | 0.4 | PDSS2 PDSS1 | Terpenoid backbone biosynthesis |
| REAC:R-HSA-8978934 | 0.0018206657072 | 0.4 | PDSS2 PDSS1 | Metabolism of cofactors |
| GO:0000010 | 0.00468200720083 | 0.4 | PDSS2 PDSS1 | trans-hexaprenyltranstransferase activity |
| GO:0097269 | 0.00468200720083 | 0.4 | PDSS2 PDSS1 | all-trans-decaprenyl-diphosphate synthase activity |
| HP:0002151 | 0.0159509868384 | 0.6 | PDSS2 PDSS1 ACAD9 | Increased serum lactate |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| ACAD9 | MTRF1L | 0.995 | 0.532 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 | |
| ACAD9 | PDSS2 | 0.988 | 0.152 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| MCCD1 | PDSS2 | 0.979 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| MCCD1 | PDSS1 | 0.972 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| ACAD9 | PDSS1 | 0.962 | 0.08 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| PDSS1 | PDSS2 | 0.744 | 0.106 | bioplex_WMM bioplex3_WMM WMM_only | |
| PDSS2 | MTRF1L | 0.164 | 0.178 | bioplex_WMM bioplex3_WMM WMM_only | |
| PDSS1 | MTRF1L | 0.143 | 0.128 | bioplex_WMM bioplex3_WMM WMM_only | |
| ACAD9 | MCCD1 | 0.014 | bioplex3_HEK293 WMM_only |
Related Complexes