hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_13960.1
Confidence: Medium  
ProteinsGenename | Protein Name | Uniprot Annotation Score | Links |
---|---|---|---|
HEXIM2 | Protein HEXIM2 (Hexamethylene bis-acetamide-inducible protein 2) | 5 | UniProt   NCBI |
ELL2 | RNA polymerase II elongation factor ELL2 | 5 | UniProt   NCBI |
CDK9 | Cyclin-dependent kinase 9 (EC 2.7.11.22) (EC 2.7.11.23) (C-2K) (Cell division cycle 2-like protein kinase 4) (Cell division protein kinase 9) (Serine/threonine-protein kinase PITALRE) (Tat-associated kinase complex catalytic subunit) | 5 | UniProt   NCBI |
CCNT2 | Cyclin-T2 (CycT2) | 5 | UniProt   NCBI |
AFF1 | AF4/FMR2 family member 1 (ALL1-fused gene from chromosome 4 protein) (Protein AF-4) (Protein FEL) (Proto-oncogene AF4) | 5 | UniProt   NCBI |
CCNT1 | Cyclin-T1 (CycT1) (Cyclin-T) | 5 | UniProt   NCBI |
MLLT3 | Protein AF-9 (ALL1-fused gene from chromosome 9 protein) (Myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein) (YEATS domain-containing protein 3) | 5 | UniProt   NCBI |
EAF2 | ELL-associated factor 2 (Testosterone-regulated apoptosis inducer and tumor suppressor protein) | 5 | UniProt   NCBI |
EAF1 | ELL-associated factor 1 | 5 | UniProt   NCBI |
ELL3 | RNA polymerase II elongation factor ELL3 | 5 | UniProt   NCBI |
HEXIM1 | Protein HEXIM1 (Cardiac lineage protein 1) (Estrogen down-regulated gene 1 protein) (Hexamethylene bis-acetamide-inducible protein 1) (Menage a quatre protein 1) | 5 | UniProt   NCBI |
ELL | RNA polymerase II elongation factor ELL (Eleven-nineteen lysine-rich leukemia protein) | 5 | UniProt   NCBI |
MLLT1 | Protein ENL (YEATS domain-containing protein 1) | 5 | UniProt   NCBI |
AFF4 | AF4/FMR2 family member 4 (ALL1-fused gene from chromosome 5q31 protein) (Protein AF-5q31) (Major CDK9 elongation factor-associated protein) | 5 | UniProt   NCBI |
ICE1 | Little elongation complex subunit 1 (Interactor of little elongator complex ELL subunit 1) | 5 | UniProt   NCBI |
Enrichments
Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
---|---|---|---|---|
  CORUM:6084 | 4.08572268262e-34 | 0.733333333333 | EAF1 CDK9 AFF4 CCNT1 CCNT2 ELL3 ELL2 ELL MLLT3 AFF1 MLLT1 | AFF4 super elongation complex (SEC) |
  GO:0008023 | 3.31677485101e-27 | 0.866666666667 | ICE1 EAF1 ELL CDK9 AFF4 CCNT1 CCNT2 EAF2 ELL2 ELL3 MLLT3 AFF1 MLLT1 | transcription elongation factor complex |
  KEGG:03250 | 3.01557964072e-17 | 0.6 | CDK9 AFF4 CCNT1 CCNT2 ELL2 ELL MLLT3 ELL3 MLLT1 | Viral life cycle - HIV-1 |
  REAC:R-HSA-112382 | 1.58363074545e-16 | 0.6 | EAF1 CDK9 CCNT1 CCNT2 MLLT1 ELL MLLT3 EAF2 AFF4 | Formation of RNA Pol II elongation complex |
  REAC:R-HSA-75955 | 1.58363074545e-16 | 0.6 | EAF1 CDK9 CCNT1 CCNT2 MLLT1 ELL MLLT3 EAF2 AFF4 | RNA Polymerase II Transcription Elongation |
  REAC:R-HSA-674695 | 3.59340887757e-15 | 0.6 | EAF1 CDK9 CCNT1 CCNT2 MLLT1 ELL MLLT3 EAF2 AFF4 | RNA Polymerase II Pre-transcription Events |
  GO:0034243 | 5.3193099913e-13 | 0.6 | EAF1 CDK9 CCNT1 CCNT2 ELL3 ELL2 ELL HEXIM1 EAF2 | regulation of transcription elongation by RNA polymerase II |
  GO:0032784 | 3.40570701162e-12 | 0.6 | EAF1 CDK9 CCNT1 CCNT2 ELL3 ELL2 ELL HEXIM1 EAF2 | regulation of DNA-templated transcription elongation |
  GO:0006368 | 5.00992705954e-12 | 0.6 | EAF1 CDK9 CCNT1 CCNT2 ELL3 ELL2 ELL HEXIM1 EAF2 | transcription elongation by RNA polymerase II |
  GO:0006354 | 2.19250594571e-11 | 0.6 | EAF1 CDK9 CCNT1 CCNT2 ELL3 ELL2 ELL HEXIM1 EAF2 | DNA-templated transcription elongation |
  REAC:R-HSA-6807505 | 9.74869871549e-11 | 0.466666666667 | CDK9 CCNT1 CCNT2 ELL2 ICE1 ELL ELL3 | RNA polymerase II transcribes snRNA genes |
  GO:0140513 | 1.30571947958e-10 | 0.933333333333 | ICE1 EAF1 ELL CDK9 AFF4 CCNT1 CCNT2 EAF2 ELL2 ELL3 MLLT3 AFF1 HEXIM1 MLLT1 | nuclear protein-containing complex |
  GO:0097322 | 1.51166065257e-09 | 0.333333333333 | CCNT1 CCNT2 HEXIM2 HEXIM1 CDK9 | 7SK snRNA binding |
  REAC:R-HSA-73857 | 5.46916717119e-09 | 0.8 | ICE1 EAF1 CDK9 AFF4 CCNT1 CCNT2 ELL3 ELL2 ELL MLLT3 EAF2 MLLT1 | RNA Polymerase II Transcription |
  REAC:R-HSA-74160 | 2.40676552113e-08 | 0.8 | ICE1 EAF1 CDK9 AFF4 CCNT1 CCNT2 ELL3 ELL2 ELL MLLT3 EAF2 MLLT1 | Gene expression (Transcription) |
  CORUM:2873 | 4.24607948444e-08 | 0.2 | CCNT1 CDK9 HEXIM1 | P-TEFb-7SKRNA-HEXIM1 complex |
  CORUM:2602 | 4.24607948444e-08 | 0.2 | CCNT1 CDK9 HEXIM1 | P-TEFb-7SKRNA-HEXIM1 complex |
  CORUM:2878 | 4.24607948444e-08 | 0.2 | CCNT1 CDK9 HEXIM1 | P-TEFb-7SKRNA-HEXIM1 complex |
  CORUM:7566 | 1.6973856751e-07 | 0.2 | CCNT1 CDK9 HEXIM1 | 7SK RNP complex |
  GO:0032968 | 1.94469454346e-07 | 0.4 | CDK9 CCNT1 CCNT2 ELL2 ELL ELL3 | positive regulation of transcription elongation by RNA polymerase II |
  KEGG:05202 | 3.40549234548e-07 | 0.4 | CDK9 CCNT1 CCNT2 MLLT1 MLLT3 AFF1 | Transcriptional misregulation in cancer |
  GO:0032786 | 7.28797700206e-07 | 0.4 | CDK9 CCNT1 CCNT2 ELL2 ELL ELL3 | positive regulation of DNA-templated transcription, elongation |
  REAC:R-HSA-167290 | 7.60450295249e-06 | 0.266666666667 | CCNT1 ELL CDK9 CCNT2 | Pausing and recovery of HIV elongation |
  REAC:R-HSA-167287 | 7.60450295249e-06 | 0.266666666667 | CCNT1 ELL CDK9 CCNT2 | HIV elongation arrest and recovery |
  GO:0010468 | 1.29882116049e-05 | 1.0 | ICE1 EAF1 ELL MLLT1 CDK9 AFF4 CCNT1 CCNT2 EAF2 HEXIM2 ELL3 MLLT3 AFF1 HEXIM1 ELL2 | regulation of gene expression |
  GO:0010556 | 2.07131089478e-05 | 1.0 | ICE1 EAF1 ELL MLLT1 CDK9 AFF4 CCNT1 CCNT2 EAF2 HEXIM2 ELL3 MLLT3 AFF1 HEXIM1 ELL2 | regulation of macromolecule biosynthetic process |
  REAC:R-HSA-167152 | 2.85004066396e-05 | 0.266666666667 | CCNT1 ELL CDK9 CCNT2 | Formation of HIV elongation complex in the absence of HIV Tat |
  GO:0017069 | 2.871912886e-05 | 0.333333333333 | CCNT1 CCNT2 HEXIM2 HEXIM1 CDK9 | snRNA binding |
  GO:0031326 | 2.88157497294e-05 | 1.0 | ICE1 EAF1 ELL MLLT1 CDK9 AFF4 CCNT1 CCNT2 EAF2 HEXIM2 ELL3 MLLT3 AFF1 HEXIM1 ELL2 | regulation of cellular biosynthetic process |
  GO:0009889 | 3.14914921943e-05 | 1.0 | ICE1 EAF1 ELL MLLT1 CDK9 AFF4 CCNT1 CCNT2 EAF2 HEXIM2 ELL3 MLLT3 AFF1 HEXIM1 ELL2 | regulation of biosynthetic process |
  GO:0042795 | 3.57366752742e-05 | 0.266666666667 | ICE1 ELL ELL2 ELL3 | snRNA transcription by RNA polymerase II |
  GO:0005654 | 3.91482406646e-05 | 1.0 | ICE1 EAF1 ELL MLLT1 CDK9 AFF4 CCNT1 CCNT2 EAF2 HEXIM2 ELL3 MLLT3 AFF1 HEXIM1 ELL2 | nucleoplasm |
  CORUM:1082 | 4.77291996201e-05 | 0.133333333333 | CCNT1 CDK9 | P-TEFb.1 complex |
  CORUM:1079 | 4.77291996201e-05 | 0.133333333333 | CCNT1 CDK9 | P-TEFb.1 complex |
  CORUM:1080 | 4.77291996201e-05 | 0.133333333333 | CDK9 CCNT2 | P-TEFb.2 complex |
  GO:0009301 | 8.4814831801e-05 | 0.266666666667 | ICE1 ELL ELL2 ELL3 | snRNA transcription |
  GO:0031981 | 0.000103206622545 | 1.0 | ICE1 EAF1 ELL MLLT1 CDK9 AFF4 CCNT1 CCNT2 EAF2 HEXIM2 ELL3 MLLT3 AFF1 HEXIM1 ELL2 | nuclear lumen |
  REAC:R-HSA-6796648 | 0.000108443381276 | 0.266666666667 | CCNT1 ELL CDK9 CCNT2 | TP53 Regulates Transcription of DNA Repair Genes |
  GO:0006355 | 0.000142975581708 | 0.866666666667 | ICE1 EAF1 ELL MLLT1 CDK9 CCNT1 CCNT2 ELL3 HEXIM2 HEXIM1 MLLT3 EAF2 ELL2 | regulation of DNA-templated transcription |
  CORUM:2603 | 0.000143102677271 | 0.133333333333 | CCNT1 CDK9 | Transcription elongation factor complex (SUPT5H, CDK9, CCNT1) |
  CORUM:2604 | 0.000143102677271 | 0.133333333333 | CCNT1 CDK9 | P-TEFb-SKP2 complex |
  CORUM:2875 | 0.000143102677271 | 0.133333333333 | CCNT1 CDK9 | BRD4-P-TEFb complex |
  CORUM:1457 | 0.000143102677271 | 0.133333333333 | AFF1 MLLT1 | AFF1-MLLT1-CBX8 complex |
  CORUM:2877 | 0.000143102677271 | 0.133333333333 | CCNT1 CDK9 | BRD4-P-TEFb complex |
  CORUM:2605 | 0.000143102677271 | 0.133333333333 | CCNT1 CDK9 | CCNT1- CDK9-GRN complex |
  GO:2001141 | 0.000154368703652 | 0.866666666667 | ICE1 EAF1 ELL MLLT1 CDK9 CCNT1 CCNT2 ELL3 HEXIM2 HEXIM1 MLLT3 EAF2 ELL2 | regulation of RNA biosynthetic process |
  REAC:R-HSA-167172 | 0.000168518635407 | 0.266666666667 | CCNT1 ELL CDK9 CCNT2 | Transcription of the HIV genome |
  GO:0006351 | 0.000260605124329 | 0.866666666667 | ICE1 EAF1 ELL MLLT1 CDK9 CCNT1 CCNT2 ELL3 HEXIM2 HEXIM1 MLLT3 EAF2 ELL2 | DNA-templated transcription |
  CORUM:2599 | 0.000286035615974 | 0.133333333333 | CCNT1 CDK9 | POLR2A-CCNT1-CDK9-NCL-LEM6-CPSF2 complex |
  CORUM:2601 | 0.000286035615974 | 0.133333333333 | CCNT1 CDK9 | P-TEFb-BRD4-TRAP220 complex |
  REAC:R-HSA-176034 | 0.000294377698256 | 0.133333333333 | CCNT1 CDK9 | Interactions of Tat with host cellular proteins |
  GO:0032774 | 0.000298346405164 | 0.866666666667 | ICE1 EAF1 ELL MLLT1 CDK9 CCNT1 CCNT2 ELL3 HEXIM2 HEXIM1 MLLT3 EAF2 ELL2 | RNA biosynthetic process |
  WP:WP3414 | 0.000349480667591 | 0.2 | CCNT1 CDK9 HEXIM1 | Initiation of transcription and translation elongation at the HIV 1 LTR |
  GO:0045893 | 0.000381888175229 | 0.666666666667 | ICE1 CDK9 CCNT1 CCNT2 ELL3 ELL2 ELL MLLT3 EAF2 MLLT1 | positive regulation of DNA-templated transcription |
  GO:1902680 | 0.000392586904043 | 0.666666666667 | ICE1 CDK9 CCNT1 CCNT2 ELL3 ELL2 ELL MLLT3 EAF2 MLLT1 | positive regulation of RNA biosynthetic process |
  GO:0060255 | 0.000421901431531 | 1.0 | ICE1 EAF1 ELL MLLT1 CDK9 AFF4 CCNT1 CCNT2 EAF2 HEXIM2 ELL3 MLLT3 AFF1 HEXIM1 ELL2 | regulation of macromolecule metabolic process |
  GO:0031323 | 0.000437112627985 | 1.0 | ICE1 EAF1 ELL MLLT1 CDK9 AFF4 CCNT1 CCNT2 EAF2 HEXIM2 ELL3 MLLT3 AFF1 HEXIM1 ELL2 | regulation of cellular metabolic process |
  GO:0051252 | 0.000588378992431 | 0.866666666667 | ICE1 EAF1 ELL MLLT1 CDK9 CCNT1 CCNT2 ELL3 HEXIM2 HEXIM1 MLLT3 EAF2 ELL2 | regulation of RNA metabolic process |
  GO:0010467 | 0.000664359312472 | 1.0 | ICE1 EAF1 ELL MLLT1 CDK9 AFF4 CCNT1 CCNT2 EAF2 HEXIM2 ELL3 MLLT3 AFF1 HEXIM1 ELL2 | gene expression |
  REAC:R-HSA-167238 | 0.00104570459746 | 0.2 | CCNT1 CDK9 ELL | Pausing and recovery of Tat-mediated HIV elongation |
  REAC:R-HSA-167243 | 0.00104570459746 | 0.2 | CCNT1 CDK9 ELL | Tat-mediated HIV elongation arrest and recovery |
  GO:0051254 | 0.00115077928473 | 0.666666666667 | ICE1 CDK9 CCNT1 CCNT2 ELL3 ELL2 ELL MLLT3 EAF2 MLLT1 | positive regulation of RNA metabolic process |
  CORUM:2600 | 0.00133166929729 | 0.133333333333 | CCNT1 CDK9 | BRD4 complex |
  GO:0034654 | 0.00145416647034 | 0.866666666667 | ICE1 EAF1 ELL MLLT1 CDK9 CCNT1 CCNT2 ELL3 HEXIM2 HEXIM1 MLLT3 EAF2 ELL2 | nucleobase-containing compound biosynthetic process |
  GO:0019222 | 0.00151343936152 | 1.0 | ICE1 EAF1 ELL MLLT1 CDK9 AFF4 CCNT1 CCNT2 EAF2 HEXIM2 ELL3 MLLT3 AFF1 HEXIM1 ELL2 | regulation of metabolic process |
  GO:0018130 | 0.00182908891309 | 0.866666666667 | ICE1 EAF1 ELL MLLT1 CDK9 CCNT1 CCNT2 ELL3 HEXIM2 HEXIM1 MLLT3 EAF2 ELL2 | heterocycle biosynthetic process |
  REAC:R-HSA-2173796 | 0.00183220931156 | 0.2 | CCNT1 CDK9 CCNT2 | SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription |
  GO:0019438 | 0.00185368644094 | 0.866666666667 | ICE1 EAF1 ELL MLLT1 CDK9 CCNT1 CCNT2 ELL3 HEXIM2 HEXIM1 MLLT3 EAF2 ELL2 | aromatic compound biosynthetic process |
  GO:0019219 | 0.00186195278483 | 0.866666666667 | ICE1 EAF1 ELL MLLT1 CDK9 CCNT1 CCNT2 ELL3 HEXIM2 HEXIM1 MLLT3 EAF2 ELL2 | regulation of nucleobase-containing compound metabolic process |
  REAC:R-HSA-162599 | 0.00226403344356 | 0.266666666667 | CCNT1 ELL CDK9 CCNT2 | Late Phase of HIV Life Cycle |
  GO:0009059 | 0.00227590295256 | 1.0 | ICE1 EAF1 ELL MLLT1 CDK9 AFF4 CCNT1 CCNT2 EAF2 HEXIM2 ELL3 MLLT3 AFF1 HEXIM1 ELL2 | macromolecule biosynthetic process |
  GO:0008024 | 0.00244160521127 | 0.2 | CCNT1 CDK9 CCNT2 | cyclin/CDK positive transcription elongation factor complex |
  GO:0070013 | 0.0026065796042 | 1.0 | ICE1 EAF1 ELL MLLT1 CDK9 AFF4 CCNT1 CCNT2 EAF2 HEXIM2 ELL3 MLLT3 AFF1 HEXIM1 ELL2 | intracellular organelle lumen |
  GO:0043233 | 0.0026065796042 | 1.0 | ICE1 EAF1 ELL MLLT1 CDK9 AFF4 CCNT1 CCNT2 EAF2 HEXIM2 ELL3 MLLT3 AFF1 HEXIM1 ELL2 | organelle lumen |
  GO:0031974 | 0.0026065796042 | 1.0 | ICE1 EAF1 ELL MLLT1 CDK9 AFF4 CCNT1 CCNT2 EAF2 HEXIM2 ELL3 MLLT3 AFF1 HEXIM1 ELL2 | membrane-enclosed lumen |
  GO:1901362 | 0.00266712285287 | 0.866666666667 | ICE1 EAF1 ELL MLLT1 CDK9 CCNT1 CCNT2 ELL3 HEXIM2 HEXIM1 MLLT3 EAF2 ELL2 | organic cyclic compound biosynthetic process |
  REAC:R-HSA-167200 | 0.0029350298624 | 0.2 | CCNT1 CDK9 ELL | Formation of HIV-1 elongation complex containing HIV-1 Tat |
  REAC:R-HSA-167169 | 0.0029350298624 | 0.2 | CCNT1 CDK9 ELL | HIV Transcription Elongation |
  REAC:R-HSA-167246 | 0.0029350298624 | 0.2 | CCNT1 CDK9 ELL | Tat-mediated elongation of the HIV-1 transcript |
  CORUM:2639 | 0.00313149612499 | 0.133333333333 | CCNT1 CDK9 | HES1 promoter-Notch enhancer complex |
  REAC:R-HSA-162587 | 0.00321242890176 | 0.266666666667 | CCNT1 ELL CDK9 CCNT2 | HIV Life Cycle |
  GO:0016538 | 0.00392911673729 | 0.266666666667 | CCNT1 HEXIM2 HEXIM1 CCNT2 | cyclin-dependent protein serine/threonine kinase regulator activity |
  GO:0045935 | 0.00411552865402 | 0.666666666667 | ICE1 CDK9 CCNT1 CCNT2 ELL3 ELL2 ELL MLLT3 EAF2 MLLT1 | positive regulation of nucleobase-containing compound metabolic process |
  GO:0006366 | 0.00440440320842 | 0.733333333333 | ICE1 EAF1 CDK9 CCNT1 CCNT2 ELL3 HEXIM2 ELL HEXIM1 EAF2 ELL2 | transcription by RNA polymerase II |
  REAC:R-HSA-2173793 | 0.00498637410589 | 0.2 | CCNT1 CDK9 CCNT2 | Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer |
  GO:0019083 | 0.00680572995739 | 0.266666666667 | CCNT1 CDK9 HEXIM1 CCNT2 | viral transcription |
  GO:0016073 | 0.00944619196099 | 0.266666666667 | ICE1 ELL ELL2 ELL3 | snRNA metabolic process |
  GO:0016070 | 0.0099762017936 | 0.866666666667 | ICE1 EAF1 ELL MLLT1 CDK9 CCNT1 CCNT2 ELL3 HEXIM2 HEXIM1 MLLT3 EAF2 ELL2 | RNA metabolic process |
  GO:0000079 | 0.0137412477933 | 0.266666666667 | CCNT1 HEXIM2 HEXIM1 CCNT2 | regulation of cyclin-dependent protein serine/threonine kinase activity |
  GO:0044249 | 0.0158161955747 | 1.0 | ICE1 EAF1 ELL MLLT1 CDK9 AFF4 CCNT1 CCNT2 EAF2 HEXIM2 ELL3 MLLT3 AFF1 HEXIM1 ELL2 | cellular biosynthetic process |
  HPA:0301362 | 0.0162052415306 | 0.4 | EAF1 CDK9 CCNT1 CCNT2 HEXIM2 HEXIM1 | lung; alveolar cells type I[>=Medium] |
  GO:0044271 | 0.0176385196416 | 0.866666666667 | ICE1 EAF1 ELL MLLT1 CDK9 CCNT1 CCNT2 ELL3 HEXIM2 HEXIM1 MLLT3 EAF2 ELL2 | cellular nitrogen compound biosynthetic process |
  GO:1901576 | 0.0178691653741 | 1.0 | ICE1 EAF1 ELL MLLT1 CDK9 AFF4 CCNT1 CCNT2 EAF2 HEXIM2 ELL3 MLLT3 AFF1 HEXIM1 ELL2 | organic substance biosynthetic process |
  GO:1904029 | 0.0181100446731 | 0.266666666667 | CCNT1 HEXIM2 HEXIM1 CCNT2 | regulation of cyclin-dependent protein kinase activity |
  REAC:R-HSA-162906 | 0.0182437077181 | 0.266666666667 | CCNT1 ELL CDK9 CCNT2 | HIV Infection |
  GO:0009058 | 0.0195692804333 | 1.0 | ICE1 EAF1 ELL MLLT1 CDK9 AFF4 CCNT1 CCNT2 EAF2 HEXIM2 ELL3 MLLT3 AFF1 HEXIM1 ELL2 | biosynthetic process |
  WP:WP4673 | 0.024165327471 | 0.2 | CCNT1 CDK9 CCNT2 | Male infertility |
  REAC:R-HSA-170834 | 0.0263575601139 | 0.2 | CCNT1 CDK9 CCNT2 | Signaling by TGF-beta Receptor Complex |
  GO:0005634 | 0.0268196035713 | 1.0 | ICE1 EAF1 ELL MLLT1 CDK9 AFF4 CCNT1 CCNT2 EAF2 HEXIM2 ELL3 MLLT3 AFF1 HEXIM1 ELL2 | nucleus |
  GO:0019908 | 0.0294840968368 | 0.2 | CCNT1 CDK9 CCNT2 | nuclear cyclin-dependent protein kinase holoenzyme complex |
  GO:0010557 | 0.0320984432836 | 0.666666666667 | ICE1 CDK9 CCNT1 CCNT2 ELL3 ELL2 ELL MLLT3 EAF2 MLLT1 | positive regulation of macromolecule biosynthetic process |
  GO:0043923 | 0.035359119817 | 0.2 | CCNT1 CDK9 CCNT2 | positive regulation by host of viral transcription |
  HPA:0090163 | 0.0374299062822 | 0.466666666667 | EAF1 CDK9 CCNT2 HEXIM2 HEXIM1 MLLT3 MLLT1 | cerebellum; Purkinje cells[High] |
  GO:0031328 | 0.0424135263571 | 0.666666666667 | ICE1 CDK9 CCNT1 CCNT2 ELL3 ELL2 ELL MLLT3 EAF2 MLLT1 | positive regulation of cellular biosynthetic process |
  GO:0009891 | 0.0450424649257 | 0.666666666667 | ICE1 CDK9 CCNT1 CCNT2 ELL3 ELL2 ELL MLLT3 EAF2 MLLT1 | positive regulation of biosynthetic process |
  GO:0090304 | 0.0459903481626 | 0.866666666667 | ICE1 EAF1 ELL MLLT1 CDK9 CCNT1 CCNT2 ELL3 HEXIM2 HEXIM1 MLLT3 EAF2 ELL2 | nucleic acid metabolic process |
  GO:0070691 | 0.0491610756088 | 0.133333333333 | CCNT1 CDK9 | P-TEFb complex |
  GO:0032806 | 0.0493379236969 | 0.2 | CCNT1 CDK9 CCNT2 | carboxy-terminal domain protein kinase complex |
  HPA:0301361 | 0.0496248018099 | 0.4 | EAF1 CDK9 CCNT1 CCNT2 HEXIM2 HEXIM1 | lung; alveolar cells type I[>=Low] |
Edges
Protein 1 | Protein 2 | Score | ProteomeHD |
---|---|---|---|
 AFF4 |  MLLT1 | 1.0 | 0.298           |
 ELL |  EAF1 | 1.0 | 0.21           |
 CDK9 |  CCNT1 | 1.0 | 0.562           |
 CDK9 |  CCNT2 | 1.0 | 0.262           |
 ELL2 |  EAF1 | 1.0 | 0.175142857143           |
 ELL3 |  EAF1 | 1.0 |            |
 AFF4 |  ELL3 | 1.0 |            |
 AFF1 |  MLLT1 | 1.0 | 0.168           |
 CDK9 |  HEXIM1 | 1.0 | 0.214           |
 CCNT1 |  HEXIM2 | 1.0 | 0.098           |
 HEXIM2 |  HEXIM1 | 1.0 | 0.072           |
 MLLT1 |  EAF1 | 1.0 | 0.264           |
 AFF4 |  EAF1 | 1.0 | 0.082           |
 CCNT2 |  HEXIM2 | 0.999 | 0.142           |
 AFF1 |  AFF4 | 0.999 | 0.134           |
 CCNT2 |  HEXIM1 | 0.999 | 0.152           |
 CCNT1 |  HEXIM1 | 0.999 | 0.278           |
 AFF1 |  ELL3 | 0.999 |            |
 MLLT3 |  AFF1 | 0.999 | 0.22           |
 EAF2 |  ELL3 | 0.999 |            |
 ELL3 |  ICE1 | 0.999 |            |
 MLLT1 |  ELL3 | 0.999 |            |
 CCNT1 |  ELL3 | 0.999 |            |
 CCNT2 |  CCNT1 | 0.999 | 0.112           |
 AFF4 |  ELL2 | 0.999 | 0.076           |
 AFF1 |  EAF1 | 0.999 | 0.086           |
 EAF2 |  EAF1 | 0.999 |            |
 EAF1 |  ICE1 | 0.999 | 0.214           |
 MLLT3 |  MLLT1 | 0.999 | 0.326           |
 AFF1 |  ELL | 0.998 | 0.18           |
 CCNT1 |  AFF4 | 0.998 | 0.134           |
 AFF4 |  ELL | 0.998 | 0.208           |
 MLLT3 |  AFF4 | 0.998 | 0.2           |
 CDK9 |  AFF1 | 0.998 | 0.112           |
 CDK9 |  HEXIM2 | 0.998 | 0.096           |
 ELL2 |  ELL | 0.998 | 0.144           |
 ELL2 |  MLLT1 | 0.998 | 0.082           |
 CDK9 |  ELL3 | 0.997 |            |
 ELL |  ICE1 | 0.997 | 0.194           |
 AFF1 |  ELL2 | 0.997 | 0.08           |
 MLLT3 |  ELL | 0.997 | 0.22           |
 MLLT1 |  ELL | 0.997 | 0.2           |
 CCNT2 |  AFF4 | 0.997 | 0.196           |
 EAF2 |  AFF4 | 0.997 |            |
 CDK9 |  AFF4 | 0.997 | 0.064           |
 CCNT1 |  MLLT1 | 0.996 | 0.196933333333           |
 MLLT3 |  ELL2 | 0.995 | 0.054           |
 CCNT1 |  ELL | 0.995 | 0.16           |
 CCNT2 |  MLLT1 | 0.994 | 0.204           |
 CDK9 |  MLLT1 | 0.994 | 0.29           |
 ELL2 |  ELL3 | 0.992 |            |
 MLLT3 |  CCNT1 | 0.989 | 0.202349206349           |
 CDK9 |  ELL2 | 0.989 | 0.098           |
 AFF1 |  EAF2 | 0.987 |            |
 CDK9 |  ELL | 0.987 | 0.202           |
 ELL |  ELL3 | 0.987 |            |
 MLLT3 |  ELL3 | 0.987 |            |
 EAF2 |  MLLT1 | 0.984 |            |
 CCNT2 |  ELL3 | 0.983 |            |
 AFF1 |  CCNT1 | 0.98 | 0.172           |
 CCNT1 |  ELL2 | 0.976 | 0.084           |
 CCNT2 |  AFF1 | 0.974 | 0.160571428571           |
 MLLT3 |  CCNT2 | 0.964 | 0.112           |
 CCNT2 |  ELL2 | 0.963 | 0.116           |
 CDK9 |  EAF1 | 0.961 | 0.244           |
 MLLT3 |  CDK9 | 0.958 | 0.206           |
 CCNT2 |  ELL | 0.949 | 0.084           |
 AFF4 |  ICE1 | 0.949 | 0.154           |
 MLLT1 |  ICE1 | 0.94 | 0.184           |
 CCNT1 |  EAF1 | 0.938 | 0.218           |
 EAF2 |  ICE1 | 0.92 |            |
 CCNT1 |  EAF2 | 0.912 |            |
 AFF1 |  ICE1 | 0.911 | 0.154           |
 MLLT1 |  HEXIM2 | 0.901 | 0.094           |
 CCNT1 |  ICE1 | 0.893 | 0.364           |
 AFF1 |  HEXIM2 | 0.875 | 0.082           |
 EAF2 |  ELL2 | 0.843 |            |
 ELL2 |  ICE1 | 0.813 | 0.128           |
 MLLT3 |  EAF1 | 0.791 | 0.33           |
 AFF4 |  HEXIM2 | 0.791 | 0.11           |
 CCNT2 |  EAF1 | 0.767 | 0.148           |
 CDK9 |  EAF2 | 0.68 |            |
 EAF2 |  ELL | 0.664 |            |
 MLLT3 |  EAF2 | 0.654 |            |
 AFF4 |  HEXIM1 | 0.578 | 0.114           |
 CDK9 |  ICE1 | 0.438 | 0.284           |
 CCNT2 |  EAF2 | 0.4 |            |
 MLLT3 |  ICE1 | 0.257 | 0.162           |
 MLLT1 |  HEXIM1 | 0.229 | 0.224           |
 AFF1 |  HEXIM1 | 0.224 | 0.072           |
 CCNT2 |  ICE1 | 0.139 | 0.19           |
 MLLT3 |  HEXIM2 | 0.126 | 0.108           |
 ELL |  HEXIM1 | 0.115 | 0.152           |
 ELL3 |  HEXIM1 | 0.084 |            |
 ELL2 |  HEXIM1 | 0.056 | 0.086           |
 MLLT3 |  HEXIM1 | 0.054 | 0.094           |
 EAF2 |  HEXIM1 | 0.052 |            |
 EAF1 |  HEXIM1 | 0.038 | 0.178           |
 ICE1 |  HEXIM1 | 0.011 | 0.215           |
Related Complexes