hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_13974.1
Complex Portal: CPX-21362
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| PCDH19 | Protocadherin-19 | 5 | UniProt NCBI |
| CDON | Cell adhesion molecule-related/down-regulated by oncogenes | 5 | UniProt NCBI |
| DCHS1 | Protocadherin-16 (Cadherin-19) (Cadherin-25) (Fibroblast cadherin-1) (Protein dachsous homolog 1) | 5 | UniProt NCBI |
| PCDHGB4 | Protocadherin gamma-B4 (PCDH-gamma-B4) (Cadherin-20) (Fibroblast cadherin-2) | 4 | UniProt NCBI |
| PCDHGB2 | Protocadherin gamma-B2 (PCDH-gamma-B2) | 4 | UniProt NCBI |
| PCDHGB1 | Protocadherin gamma-B1 (PCDH-gamma-B1) | 4 | UniProt NCBI |
| PCDHGB7 | Protocadherin gamma-B7 (PCDH-gamma-B7) | 4 | UniProt NCBI |
| PCDHGB3 | Protocadherin gamma-B3 (PCDH-gamma-B3) | 4 | UniProt NCBI |
| PCDHGB6 | Protocadherin gamma-B6 (PCDH-gamma-B6) | 4 | UniProt NCBI |
| C18orf32 | UPF0729 protein C18orf32 (Putative NF-kappa-B-activating protein 200) | 4 | UniProt NCBI |
| PCDH12 | Protocadherin-12 (Vascular cadherin-2) (Vascular endothelial cadherin-2) (VE-cad-2) (VE-cadherin-2) [Cleaved into: Protocadherin-12, secreted form] | 5 | UniProt NCBI |
| PCDHGA11 | Protocadherin gamma-A11 (PCDH-gamma-A11) | 4 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0007155 | 3.17311622092e-08 | 0.916666666667 | PCDHGB2 PCDHGB7 PCDH19 DCHS1 PCDHGB3 PCDHGB6 PCDHGB4 PCDHGA11 CDON PCDH12 PCDHGB1 | cell adhesion |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| PCDHGB2 | PCDHGB7 | 0.998 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| PCDHGB2 | PCDHGB6 | 0.998 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| PCDHGB1 | PCDHGB4 | 0.997 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| PCDHGB1 | PCDHGB2 | 0.997 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| PCDHGB3 | PCDHGB2 | 0.996 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only | |
| PCDH19 | PCDHGB1 | 0.995 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| PCDHGB1 | PCDHGB3 | 0.994 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| PCDHGB4 | PCDHGB2 | 0.993 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only | |
| PCDHGB4 | PCDHGB3 | 0.992 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| PCDHGB1 | CDON | 0.983 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| PCDHGB1 | PCDHGA11 | 0.98 |
mutually_exclusive (Q9Y5G2)
structurally_consistent (dimer) |
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| DCHS1 | PCDHGB1 | 0.979 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| PCDH12 | CDON | 0.966 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| PCDHGA11 | CDON | 0.961 | bioplex_WMM bioplex3_WMM WMM_only | ||
| PCDHGB2 | PCDHGA11 | 0.959 |
mutually_exclusive (Q9Y5G3)
structurally_consistent (dimer) |
bioplex3_HEK293 bioplex_WMM bioplex3_WMM WMM_only | |
| PCDH12 | PCDHGA11 | 0.956 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| PCDH19 | PCDH12 | 0.939 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| PCDH19 | PCDHGB2 | 0.933 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM WMM_only | ||
| PCDHGB4 | PCDHGB7 | 0.931 |
mutually_exclusive (Q9Y5G2)
|
bioplex3_WMM WMM_only | |
| PCDHGB3 | PCDHGB7 | 0.923 |
mutually_exclusive (Q9Y5G2)
|
bioplex3_WMM WMM_only | |
| PCDHGB4 | PCDHGB6 | 0.905 |
mutually_exclusive (Q9Y5G2)
|
bioplex3_WMM WMM_only | |
| CDON | C18orf32 | 0.904 | bioplex3_WMM WMM_only | ||
| PCDHGB3 | PCDHGB6 | 0.826 |
mutually_exclusive (Q9Y5G2)
|
bioplex3_WMM WMM_only | |
| PCDHGB7 | PCDHGA11 | 0.796 |
mutually_exclusive (Q9Y5G2)
|
bioplex3_WMM WMM_only | |
| PCDHGB6 | PCDHGA11 | 0.796 |
mutually_exclusive (Q9Y5G2)
|
bioplex3_WMM WMM_only | |
| PCDHGB7 | PCDHGB6 | 0.744 |
mutually_exclusive (Q9Y5G2)
|
bioplex3_WMM WMM_only | |
| PCDHGB7 | CDON | 0.715 | bioplex3_WMM WMM_only | ||
| PCDHGB6 | CDON | 0.675 | bioplex3_WMM WMM_only | ||
| PCDHGB2 | CDON | 0.651 | bioplex_WMM bioplex3_WMM WMM_only | ||
| PCDH19 | CDON | 0.559 | bioplex_WMM bioplex3_WMM WMM_only | ||
| DCHS1 | PCDHGA11 | 0.454 | bioplex_WMM bioplex3_WMM WMM_only | ||
| PCDH19 | DCHS1 | 0.428 | bioplex_WMM bioplex3_WMM WMM_only | ||
| PCDH19 | PCDHGA11 | 0.35 | bioplex_WMM bioplex3_WMM WMM_only | ||
| PCDH19 | PCDHGB4 | 0.265 | bioplex_WMM bioplex3_WMM WMM_only | ||
| PCDH19 | PCDHGB3 | 0.262 | bioplex_WMM bioplex3_WMM WMM_only | ||
| PCDHGB3 | PCDHGA11 | 0.237 | bioplex_WMM bioplex3_WMM WMM_only | ||
| PCDHGB4 | PCDHGA11 | 0.218 | bioplex_WMM bioplex3_WMM WMM_only | ||
| DCHS1 | PCDHGB2 | 0.213 | bioplex_WMM bioplex3_WMM WMM_only | ||
| DCHS1 | PCDHGB3 | 0.189 | bioplex_WMM bioplex3_WMM WMM_only | ||
| DCHS1 | CDON | 0.165 | bioplex_WMM bioplex3_WMM WMM_only | ||
| DCHS1 | PCDHGB4 | 0.164 | bioplex_WMM bioplex3_WMM WMM_only | ||
| PCDHGB4 | CDON | 0.143 | bioplex_WMM bioplex3_WMM WMM_only | ||
| PCDHGB3 | CDON | 0.143 | bioplex_WMM bioplex3_WMM WMM_only | ||
| PCDH19 | PCDHGB7 | 0.113 | bioplex3_WMM WMM_only | ||
| PCDH19 | PCDHGB6 | 0.095 | bioplex3_WMM WMM_only |
Related Complexes